Condition | Gene | Description | Fitness | Cons. |
1-ethyl-3-methylimidazolium acetate | Ga0059261_4203 | Arabinose efflux permease | -1.7 | |
1-ethyl-3-methylimidazolium chloride | Ga0059261_4203 | Arabinose efflux permease | -3.7 | |
5-Hydroxymethylfurfural | Ga0059261_3685 | Enoyl-CoA hydratase/carnithine racemase | -2.3 | |
Bacitracin | Ga0059261_0638 | type I secretion outer membrane protein, TolC family | -4.5 | |
Bacitracin | Ga0059261_0814 | hypothetical protein | -1.4 | |
Bacitracin | Ga0059261_1877 | Cation/multidrug efflux pump | -4.5 | Yes |
Bacitracin | Ga0059261_1878 | RND family efflux transporter, MFP subunit | -3.7 | |
Bacitracin | Ga0059261_4145 | phage shock protein C (PspC) family protein | -3.9 | Yes |
Bacitracin | Ga0059261_4146 | phage shock protein B | -3.6 | |
Bacitracin | Ga0059261_4149 | psp operon transcriptional activator PspF | -4.9 | Yes |
Benzalkonium Chloride | Ga0059261_0211 | Uncharacterized protein conserved in bacteria | -1.3 | Yes |
Benzalkonium Chloride | Ga0059261_2291 | putative efflux protein, MATE family | -1.2 | Yes |
Cephalothin sodium salt | Ga0059261_0243 | Major Facilitator Superfamily | -4.1 | |
Cephalothin sodium salt | Ga0059261_3143 | Zn-dependent hydrolases, including glyoxylases | -3.7 | |
Choline Lysine | Ga0059261_1959 | Predicted permease, DMT superfamily | -5.3 | |
Choline chloride | Ga0059261_2271 | branched-chain alpha-keto acid dehydrogenase E2 component (EC 2.3.1.168) | -1.4 | |
Choline chloride | Ga0059261_2272 | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit | -1.1 | |
Choline chloride | Ga0059261_3685 | Enoyl-CoA hydratase/carnithine racemase | -3.0 | |
Cisplatin | Ga0059261_0249 | Superfamily I DNA and RNA helicases | -4.6 | Yes |
Cisplatin | Ga0059261_0645 | DNA replication and repair protein RecR | -5.1 | Yes |
Cisplatin | Ga0059261_0674 | excinuclease ABC, A subunit | -4.4 | Yes |
Cisplatin | Ga0059261_0751 | DNA repair protein RadA | -1.1 | Yes |
Cisplatin | Ga0059261_0958 | ATP-dependent DNA helicase RecG (EC 3.6.1.-) | -1.6 | Yes |
Cisplatin | Ga0059261_0960 | transcription-repair coupling factor (mfd) | -1.3 | Yes |
Cisplatin | Ga0059261_1941 | DNA damage response helicase, ligase-associated (from data) | -4.0 | Yes |
Cisplatin | Ga0059261_3186 | Excinuclease ABC subunit C | -3.8 | Yes |
Cisplatin | Ga0059261_3189 | DNA replication and repair protein RecO | -5.1 | Yes |
Cisplatin | Ga0059261_3779 | Excinuclease ABC subunit B | -4.2 | Yes |
Cobalt chloride hexahydrate | Ga0059261_0852 | Transcriptional regulators | -1.4 | |
D-Cycloserine | Ga0059261_2678 | DNA-binding ferritin-like protein (oxidative damage protectant) | -4.9 | Yes |
Doxycycline hyclate | Ga0059261_2714 | drug resistance transporter, Bcr/CflA subfamily | -1.4 | |
Fusidic acid sodium salt | Ga0059261_0120 | lytic murein transglycosylase | -1.8 | |
Fusidic acid sodium salt | Ga0059261_0638 | type I secretion outer membrane protein, TolC family | -2.1 | |
Fusidic acid sodium salt | Ga0059261_1450 | Opacity protein and related surface antigens | -1.0 | |
Fusidic acid sodium salt | Ga0059261_1513 | hypothetical protein | -2.2 | |
Fusidic acid sodium salt | Ga0059261_2146 | Glyoxalase-like domain | -1.7 | |
Fusidic acid sodium salt | Ga0059261_2697 | Membrane carboxypeptidase/penicillin-binding protein | -1.2 | |
Fusidic acid sodium salt | Ga0059261_2714 | drug resistance transporter, Bcr/CflA subfamily | -1.6 | Yes |
Fusidic acid sodium salt | Ga0059261_2754 | ABC-type branched-chain amino acid transport systems, periplasmic component | -1.3 | |
Fusidic acid sodium salt | Ga0059261_3200 | Opacity protein and related surface antigens | -2.1 | |
Fusidic acid sodium salt | Ga0059261_3431 | Uncharacterized protein conserved in bacteria | -1.1 | |
Fusidic acid sodium salt | Ga0059261_3780 | hypothetical protein | -1.2 | |
Fusidic acid sodium salt | Ga0059261_4005 | drug resistance transporter, EmrB/QacA subfamily | -2.3 | Yes |
Fusidic acid sodium salt | Ga0059261_4006 | Multidrug resistance efflux pump | -1.9 | |
Gentamicin sulfate salt | Ga0059261_1482 | Acetyltransferase (GNAT) family | -2.9 | Yes |
Gentamicin sulfate salt | Ga0059261_1483 | acetyl-CoA acetyltransferases | -2.0 | |
Gentamicin sulfate salt | Ga0059261_2137 | ABC-type multidrug transport system, ATPase and permease components | -2.3 | |
L-Lysine | Ga0059261_1404 | transcriptional regulator, BadM/Rrf2 family | -1.5 | |
L-Lysine | Ga0059261_1958 | Transcriptional regulators | -4.5 | |
L-Lysine | Ga0059261_1959 | Predicted permease, DMT superfamily | -5.8 | |
L-Lysine | Ga0059261_2014 | Predicted permease | -1.4 | |
L-Lysine | Ga0059261_2222 | Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family | -1.1 | |
L-Lysine | Ga0059261_3685 | Enoyl-CoA hydratase/carnithine racemase | -1.8 | |
Lomefloxacin hydrochloride | Ga0059261_0751 | DNA repair protein RadA | -2.3 | Yes |
Lomefloxacin hydrochloride | Ga0059261_3937 | Imidazolonepropionase and related amidohydrolases | +2.5 | Yes |
MreB Perturbing Compound A22 | Ga0059261_3865 | cytochrome bd-I ubiquinol oxidase subunit 1 apoprotein (EC 1.10.3.10) | -1.6 | |
MreB Perturbing Compound A22 | Ga0059261_3866 | cytochrome bd-I ubiquinol oxidase subunit 2 apoprotein (EC 1.10.3.10) | -1.6 | |
Nalidixic acid sodium salt | Ga0059261_0751 | DNA repair protein RadA | -1.4 | Yes |
Nalidixic acid sodium salt | Ga0059261_3937 | Imidazolonepropionase and related amidohydrolases | +2.0 | |
Nickel (II) chloride hexahydrate | Ga0059261_1206 | Arabinose efflux permease | -2.3 | Yes |
Nickel (II) chloride hexahydrate | Ga0059261_1210 | heavy metal efflux pump, CzcA family | -1.8 | |
Nickel (II) chloride hexahydrate | Ga0059261_1211 | HlyD family secretion protein | -2.0 | |
Nickel (II) chloride hexahydrate | Ga0059261_1212 | Outer membrane protein | -1.8 | |
Paraquat dichloride | Ga0059261_4203 | Arabinose efflux permease | -2.8 | |
Phosphomycin disodium salt | Ga0059261_0224 | Exopolyphosphatase | -1.9 | |
Phosphomycin disodium salt | Ga0059261_0243 | Major Facilitator Superfamily | -3.1 | |
Phosphomycin disodium salt | Ga0059261_0920 | rRNA methylases | -2.3 | |
Phosphomycin disodium salt | Ga0059261_0952 | Uncharacterized protein conserved in bacteria | -3.4 | |
Phosphomycin disodium salt | Ga0059261_0953 | hypothetical protein | -2.9 | |
Phosphomycin disodium salt | Ga0059261_1319 | EamA-like transporter family | -3.4 | Yes |
Phosphomycin disodium salt | Ga0059261_4001 | NTP pyrophosphohydrolases including oxidative damage repair enzymes | +1.5 | |
Phosphomycin disodium salt | Ga0059261_4002 | Esterase/lipase | +1.1 | |
Phosphomycin disodium salt | Ga0059261_4024 | Predicted phosphotransferase related to Ser/Thr protein kinases | -3.5 | Yes |
Polymyxin B sulfate | Ga0059261_0638 | type I secretion outer membrane protein, TolC family | -2.4 | |
Polymyxin B sulfate | Ga0059261_0741 | Domain of unknown function (DUF4403) | -3.8 | |
Polymyxin B sulfate | Ga0059261_1877 | Cation/multidrug efflux pump | -1.6 | |
Polymyxin B sulfate | Ga0059261_1878 | RND family efflux transporter, MFP subunit | -1.2 | |
Polymyxin B sulfate | Ga0059261_3340 | Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) | -1.8 | |
Polymyxin B sulfate | Ga0059261_3876 | Signal transduction histidine kinase | -1.9 | |
Polymyxin B sulfate | Ga0059261_3878 | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | -1.9 | |
Polymyxin B sulfate | Ga0059261_3879 | outer membrane autotransporter barrel domain | -1.9 | |
Rifampicin | Ga0059261_0257 | hypothetical protein | -2.0 | |
Rifampicin | Ga0059261_0638 | type I secretion outer membrane protein, TolC family | -4.9 | |
Rifampicin | Ga0059261_0734 | RNA | -4.0 | |
Rifampicin | Ga0059261_1273 | DnaJ domain | -4.0 | Yes |
Rifampicin | Ga0059261_1877 | Cation/multidrug efflux pump | -5.1 | |
Rifampicin | Ga0059261_1878 | RND family efflux transporter, MFP subunit | -4.2 | |
Rifampicin | Ga0059261_3200 | Opacity protein and related surface antigens | -1.2 | |
Rifampicin | Ga0059261_3374 | NAD-dependent aldehyde dehydrogenases | -1.4 | |
Rifampicin | Ga0059261_4135 | DnaJ domain | -2.3 | |
Rifampicin | Ga0059261_4149 | psp operon transcriptional activator PspF | -1.9 | |
Sisomicin sulfate salt | Ga0059261_1482 | Acetyltransferase (GNAT) family | -5.9 | Yes |
Sisomicin sulfate salt | Ga0059261_1483 | acetyl-CoA acetyltransferases | -4.8 | |
Sisomicin sulfate salt | Ga0059261_2137 | ABC-type multidrug transport system, ATPase and permease components | -1.7 | |
Sisomicin sulfate salt | Ga0059261_3209 | queuosine biosynthesis protein QueC | -1.2 | |
Sisomicin sulfate salt | Ga0059261_3340 | Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) | -2.1 | |
Sodium Chlorite | Ga0059261_3625 | Short-chain dehydrogenases of various substrate specificities | -1.8 | |
Sodium Chlorite | Ga0059261_3865 | cytochrome bd-I ubiquinol oxidase subunit 1 apoprotein (EC 1.10.3.10) | -1.9 | Yes |
Sodium Chlorite | Ga0059261_3866 | cytochrome bd-I ubiquinol oxidase subunit 2 apoprotein (EC 1.10.3.10) | -2.0 | Yes |
Sodium Chlorite | Ga0059261_4008 | Alpha/beta hydrolase family | -1.0 | |
Spectinomycin dihydrochloride pentahydrate | Ga0059261_2137 | ABC-type multidrug transport system, ATPase and permease components | -3.6 | Yes |
Tetracycline hydrochloride | Ga0059261_2714 | drug resistance transporter, Bcr/CflA subfamily | -1.9 | Yes |
Thallium(I) acetate | Ga0059261_1942 | putative efflux pump, required for thallium (I) resistance (from data) | -4.1 | Yes |
Vanillin | Ga0059261_0530 | 4-carboxy-2-hydroxymuconate semialdehyde dehydrogenase (EC 1.1.1.-) | -4.1 | |
Vanillin | Ga0059261_3683 | Enoyl-CoA hydratase/carnithine racemase | -1.2 | |
Vanillin | Ga0059261_3685 | Enoyl-CoA hydratase/carnithine racemase | -2.4 | |
Zinc sulfate heptahydrate | Ga0059261_2678 | DNA-binding ferritin-like protein (oxidative damage protectant) | -5.4 | |
Zinc sulfate heptahydrate | Ga0059261_3033 | ATPase, P-type (transporting), HAD superfamily, subfamily IC/heavy metal translocating P-type ATPase | -3.5 | Yes |
Zinc sulfate heptahydrate | Ga0059261_3035 | heavy metal efflux pump, CzcA family | -2.2 | Yes |
Zinc sulfate heptahydrate | Ga0059261_3036 | RND family efflux transporter, MFP subunit | -1.8 | Yes |
Zinc sulfate heptahydrate | Ga0059261_3037 | Outer membrane protein | -1.2 | Yes |
benzoic acid | Ga0059261_2618 | Protein of unknown function (DUF2721) | +1.5 | |
copper (II) chloride dihydrate | Ga0059261_2952 | RNA polymerase sigma factor, sigma-70 family | -5.1 | |
copper (II) chloride dihydrate | Ga0059261_2953 | copper-resistance protein, CopA family | -3.9 | Yes |
copper (II) chloride dihydrate | Ga0059261_2954 | Uncharacterized protein involved in copper resistance | -4.7 | |
methylglyoxal | Ga0059261_0155 | peroxiredoxin | -1.5 | |
methylglyoxal | Ga0059261_0156 | alkyl hydroperoxide reductase subunit F | -1.9 | Yes |
methylglyoxal | Ga0059261_0249 | Superfamily I DNA and RNA helicases | -2.1 | |
methylglyoxal | Ga0059261_0645 | DNA replication and repair protein RecR | -3.1 | Yes |
methylglyoxal | Ga0059261_0674 | excinuclease ABC, A subunit | -1.9 | Yes |
methylglyoxal | Ga0059261_0751 | DNA repair protein RadA | -1.4 | Yes |
methylglyoxal | Ga0059261_0758 | ATPase related to the helicase subunit of the Holliday junction resolvase | -1.4 | |
methylglyoxal | Ga0059261_0958 | ATP-dependent DNA helicase RecG (EC 3.6.1.-) | -1.8 | Yes |
methylglyoxal | Ga0059261_2759 | hydroxyacylglutathione hydrolase | -3.8 | Yes |
methylglyoxal | Ga0059261_2761 | Lactoylglutathione lyase and related lyases | -4.0 | Yes |
methylglyoxal | Ga0059261_3186 | Excinuclease ABC subunit C | -2.5 | Yes |
methylglyoxal | Ga0059261_3189 | DNA replication and repair protein RecO | -3.7 | |
methylglyoxal | Ga0059261_3779 | Excinuclease ABC subunit B | -2.1 | Yes |
methylglyoxal | Ga0059261_4215 | Predicted N-formylglutamate amidohydrolase | -1.5 | |
sodium fluoride | Ga0059261_1032 | protein CrcB | -5.6 | Yes |