Specific Phenotypes for Sphingomonas koreensis DSMZ 15582 in stress experiments

Condition Gene Description Fitness Cons.
1-ethyl-3-methylimidazolium acetate Ga0059261_4203 Arabinose efflux permease -1.7  
1-ethyl-3-methylimidazolium chloride Ga0059261_4203 Arabinose efflux permease -3.7  
5-Hydroxymethylfurfural Ga0059261_3685 Enoyl-CoA hydratase/carnithine racemase -2.3  
Bacitracin Ga0059261_0638 type I secretion outer membrane protein, TolC family -4.5  
Bacitracin Ga0059261_0814 hypothetical protein -1.4  
Bacitracin Ga0059261_1877 Cation/multidrug efflux pump -4.5 Yes
Bacitracin Ga0059261_1878 RND family efflux transporter, MFP subunit -3.7  
Bacitracin Ga0059261_4145 phage shock protein C (PspC) family protein -3.9 Yes
Bacitracin Ga0059261_4146 phage shock protein B -3.6  
Bacitracin Ga0059261_4149 psp operon transcriptional activator PspF -4.9 Yes
Benzalkonium Chloride Ga0059261_0211 Uncharacterized protein conserved in bacteria -1.3 Yes
Benzalkonium Chloride Ga0059261_2291 putative efflux protein, MATE family -1.2 Yes
Cephalothin sodium salt Ga0059261_0243 Major Facilitator Superfamily -4.1  
Cephalothin sodium salt Ga0059261_3143 Zn-dependent hydrolases, including glyoxylases -3.7  
Choline Lysine Ga0059261_1959 Predicted permease, DMT superfamily -5.3  
Choline chloride Ga0059261_2271 branched-chain alpha-keto acid dehydrogenase E2 component (EC 2.3.1.168) -1.4  
Choline chloride Ga0059261_2272 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit -1.1  
Choline chloride Ga0059261_3685 Enoyl-CoA hydratase/carnithine racemase -3.0  
Cisplatin Ga0059261_0249 Superfamily I DNA and RNA helicases -4.6 Yes
Cisplatin Ga0059261_0645 DNA replication and repair protein RecR -5.1 Yes
Cisplatin Ga0059261_0674 excinuclease ABC, A subunit -4.4 Yes
Cisplatin Ga0059261_0751 DNA repair protein RadA -1.1 Yes
Cisplatin Ga0059261_0958 ATP-dependent DNA helicase RecG (EC 3.6.1.-) -1.6 Yes
Cisplatin Ga0059261_0960 transcription-repair coupling factor (mfd) -1.3 Yes
Cisplatin Ga0059261_1941 DNA damage response helicase, ligase-associated (from data) -4.0 Yes
Cisplatin Ga0059261_3186 Excinuclease ABC subunit C -3.8 Yes
Cisplatin Ga0059261_3189 DNA replication and repair protein RecO -5.1 Yes
Cisplatin Ga0059261_3779 Excinuclease ABC subunit B -4.2 Yes
Cobalt chloride hexahydrate Ga0059261_0852 Transcriptional regulators -1.4  
D-Cycloserine Ga0059261_2678 DNA-binding ferritin-like protein (oxidative damage protectant) -4.9 Yes
Doxycycline hyclate Ga0059261_2714 drug resistance transporter, Bcr/CflA subfamily -1.4  
Fusidic acid sodium salt Ga0059261_0120 lytic murein transglycosylase -1.8  
Fusidic acid sodium salt Ga0059261_0638 type I secretion outer membrane protein, TolC family -2.1  
Fusidic acid sodium salt Ga0059261_1450 Opacity protein and related surface antigens -1.0  
Fusidic acid sodium salt Ga0059261_1513 hypothetical protein -2.2  
Fusidic acid sodium salt Ga0059261_2146 Glyoxalase-like domain -1.7  
Fusidic acid sodium salt Ga0059261_2697 Membrane carboxypeptidase/penicillin-binding protein -1.2  
Fusidic acid sodium salt Ga0059261_2714 drug resistance transporter, Bcr/CflA subfamily -1.6 Yes
Fusidic acid sodium salt Ga0059261_2754 ABC-type branched-chain amino acid transport systems, periplasmic component -1.3  
Fusidic acid sodium salt Ga0059261_3200 Opacity protein and related surface antigens -2.1  
Fusidic acid sodium salt Ga0059261_3431 Uncharacterized protein conserved in bacteria -1.1  
Fusidic acid sodium salt Ga0059261_3780 hypothetical protein -1.2  
Fusidic acid sodium salt Ga0059261_4005 drug resistance transporter, EmrB/QacA subfamily -2.3 Yes
Fusidic acid sodium salt Ga0059261_4006 Multidrug resistance efflux pump -1.9  
Gentamicin sulfate salt Ga0059261_1482 Acetyltransferase (GNAT) family -2.9 Yes
Gentamicin sulfate salt Ga0059261_1483 acetyl-CoA acetyltransferases -2.0  
Gentamicin sulfate salt Ga0059261_2137 ABC-type multidrug transport system, ATPase and permease components -2.3  
L-Lysine Ga0059261_1404 transcriptional regulator, BadM/Rrf2 family -1.5  
L-Lysine Ga0059261_1958 Transcriptional regulators -4.5  
L-Lysine Ga0059261_1959 Predicted permease, DMT superfamily -5.8  
L-Lysine Ga0059261_2014 Predicted permease -1.4  
L-Lysine Ga0059261_2222 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family -1.1  
L-Lysine Ga0059261_3685 Enoyl-CoA hydratase/carnithine racemase -1.8  
Lomefloxacin hydrochloride Ga0059261_0751 DNA repair protein RadA -2.3 Yes
Lomefloxacin hydrochloride Ga0059261_3937 Imidazolonepropionase and related amidohydrolases +2.5 Yes
MreB Perturbing Compound A22 Ga0059261_3865 cytochrome bd-I ubiquinol oxidase subunit 1 apoprotein (EC 1.10.3.10) -1.6  
MreB Perturbing Compound A22 Ga0059261_3866 cytochrome bd-I ubiquinol oxidase subunit 2 apoprotein (EC 1.10.3.10) -1.6  
Nalidixic acid sodium salt Ga0059261_0751 DNA repair protein RadA -1.4 Yes
Nalidixic acid sodium salt Ga0059261_3937 Imidazolonepropionase and related amidohydrolases +2.0  
Nickel (II) chloride hexahydrate Ga0059261_1206 Arabinose efflux permease -2.3 Yes
Nickel (II) chloride hexahydrate Ga0059261_1210 heavy metal efflux pump, CzcA family -1.8  
Nickel (II) chloride hexahydrate Ga0059261_1211 HlyD family secretion protein -2.0  
Nickel (II) chloride hexahydrate Ga0059261_1212 Outer membrane protein -1.8  
Paraquat dichloride Ga0059261_4203 Arabinose efflux permease -2.8  
Phosphomycin disodium salt Ga0059261_0224 Exopolyphosphatase -1.9  
Phosphomycin disodium salt Ga0059261_0243 Major Facilitator Superfamily -3.1  
Phosphomycin disodium salt Ga0059261_0920 rRNA methylases -2.3  
Phosphomycin disodium salt Ga0059261_0952 Uncharacterized protein conserved in bacteria -3.4  
Phosphomycin disodium salt Ga0059261_0953 hypothetical protein -2.9  
Phosphomycin disodium salt Ga0059261_1319 EamA-like transporter family -3.4 Yes
Phosphomycin disodium salt Ga0059261_4001 NTP pyrophosphohydrolases including oxidative damage repair enzymes +1.5  
Phosphomycin disodium salt Ga0059261_4002 Esterase/lipase +1.1  
Phosphomycin disodium salt Ga0059261_4024 Predicted phosphotransferase related to Ser/Thr protein kinases -3.5 Yes
Polymyxin B sulfate Ga0059261_0638 type I secretion outer membrane protein, TolC family -2.4  
Polymyxin B sulfate Ga0059261_0741 Domain of unknown function (DUF4403) -3.8  
Polymyxin B sulfate Ga0059261_1877 Cation/multidrug efflux pump -1.6  
Polymyxin B sulfate Ga0059261_1878 RND family efflux transporter, MFP subunit -1.2  
Polymyxin B sulfate Ga0059261_3340 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) -1.8  
Polymyxin B sulfate Ga0059261_3876 Signal transduction histidine kinase -1.9  
Polymyxin B sulfate Ga0059261_3878 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain -1.9  
Polymyxin B sulfate Ga0059261_3879 outer membrane autotransporter barrel domain -1.9  
Rifampicin Ga0059261_0257 hypothetical protein -2.0  
Rifampicin Ga0059261_0638 type I secretion outer membrane protein, TolC family -4.9  
Rifampicin Ga0059261_0734 RNA -4.0  
Rifampicin Ga0059261_1273 DnaJ domain -4.0 Yes
Rifampicin Ga0059261_1877 Cation/multidrug efflux pump -5.1  
Rifampicin Ga0059261_1878 RND family efflux transporter, MFP subunit -4.2  
Rifampicin Ga0059261_3200 Opacity protein and related surface antigens -1.2  
Rifampicin Ga0059261_3374 NAD-dependent aldehyde dehydrogenases -1.4  
Rifampicin Ga0059261_4135 DnaJ domain -2.3  
Rifampicin Ga0059261_4149 psp operon transcriptional activator PspF -1.9  
Sisomicin sulfate salt Ga0059261_1482 Acetyltransferase (GNAT) family -5.9 Yes
Sisomicin sulfate salt Ga0059261_1483 acetyl-CoA acetyltransferases -4.8  
Sisomicin sulfate salt Ga0059261_2137 ABC-type multidrug transport system, ATPase and permease components -1.7  
Sisomicin sulfate salt Ga0059261_3209 queuosine biosynthesis protein QueC -1.2  
Sisomicin sulfate salt Ga0059261_3340 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) -2.1  
Sodium Chlorite Ga0059261_3625 Short-chain dehydrogenases of various substrate specificities -1.8  
Sodium Chlorite Ga0059261_3865 cytochrome bd-I ubiquinol oxidase subunit 1 apoprotein (EC 1.10.3.10) -1.9 Yes
Sodium Chlorite Ga0059261_3866 cytochrome bd-I ubiquinol oxidase subunit 2 apoprotein (EC 1.10.3.10) -2.0 Yes
Sodium Chlorite Ga0059261_4008 Alpha/beta hydrolase family -1.0  
Spectinomycin dihydrochloride pentahydrate Ga0059261_2137 ABC-type multidrug transport system, ATPase and permease components -3.6 Yes
Tetracycline hydrochloride Ga0059261_2714 drug resistance transporter, Bcr/CflA subfamily -1.9 Yes
Thallium(I) acetate Ga0059261_1942 putative efflux pump, required for thallium (I) resistance (from data) -4.1 Yes
Vanillin Ga0059261_0530 4-carboxy-2-hydroxymuconate semialdehyde dehydrogenase (EC 1.1.1.-) -4.1  
Vanillin Ga0059261_3683 Enoyl-CoA hydratase/carnithine racemase -1.2  
Vanillin Ga0059261_3685 Enoyl-CoA hydratase/carnithine racemase -2.4  
Zinc sulfate heptahydrate Ga0059261_2678 DNA-binding ferritin-like protein (oxidative damage protectant) -5.4  
Zinc sulfate heptahydrate Ga0059261_3033 ATPase, P-type (transporting), HAD superfamily, subfamily IC/heavy metal translocating P-type ATPase -3.5 Yes
Zinc sulfate heptahydrate Ga0059261_3035 heavy metal efflux pump, CzcA family -2.2 Yes
Zinc sulfate heptahydrate Ga0059261_3036 RND family efflux transporter, MFP subunit -1.8 Yes
Zinc sulfate heptahydrate Ga0059261_3037 Outer membrane protein -1.2 Yes
benzoic acid Ga0059261_2618 Protein of unknown function (DUF2721) +1.5  
copper (II) chloride dihydrate Ga0059261_2952 RNA polymerase sigma factor, sigma-70 family -5.1  
copper (II) chloride dihydrate Ga0059261_2953 copper-resistance protein, CopA family -3.9 Yes
copper (II) chloride dihydrate Ga0059261_2954 Uncharacterized protein involved in copper resistance -4.7  
methylglyoxal Ga0059261_0155 peroxiredoxin -1.5  
methylglyoxal Ga0059261_0156 alkyl hydroperoxide reductase subunit F -1.9 Yes
methylglyoxal Ga0059261_0249 Superfamily I DNA and RNA helicases -2.1  
methylglyoxal Ga0059261_0645 DNA replication and repair protein RecR -3.1 Yes
methylglyoxal Ga0059261_0674 excinuclease ABC, A subunit -1.9 Yes
methylglyoxal Ga0059261_0751 DNA repair protein RadA -1.4 Yes
methylglyoxal Ga0059261_0758 ATPase related to the helicase subunit of the Holliday junction resolvase -1.4  
methylglyoxal Ga0059261_0958 ATP-dependent DNA helicase RecG (EC 3.6.1.-) -1.8 Yes
methylglyoxal Ga0059261_2759 hydroxyacylglutathione hydrolase -3.8 Yes
methylglyoxal Ga0059261_2761 Lactoylglutathione lyase and related lyases -4.0 Yes
methylglyoxal Ga0059261_3186 Excinuclease ABC subunit C -2.5 Yes
methylglyoxal Ga0059261_3189 DNA replication and repair protein RecO -3.7  
methylglyoxal Ga0059261_3779 Excinuclease ABC subunit B -2.1 Yes
methylglyoxal Ga0059261_4215 Predicted N-formylglutamate amidohydrolase -1.5  
sodium fluoride Ga0059261_1032 protein CrcB -5.6 Yes