| Condition | Gene | Description | Fitness | Cons. |
|---|
| Amikacin disulfate salt | BBR_RS10715 | tRNA-guanine(34) transglycosylase | -1.0 | |
| Amikacin disulfate salt | BBR_RS13015 | peptide deformylase | -1.4 | |
| Amikacin disulfate salt | BBR_RS14100 | UPF0182 family protein | -1.8 | |
| Amikacin disulfate salt | BBR_RS14605 | ABC transporter permease | -1.3 | |
| Amikacin disulfate salt | BBR_RS16585 | BAX inhibitor (BI)-1/YccA family protein | -2.5 | |
| Amoxicillin | BBR_RS18645 | DNA-binding response regulator | +1.4 | |
| Aztreonam | BBR_RS13430 | hypothetical protein | +1.1 | |
| Aztreonam | BBR_RS18645 | DNA-binding response regulator | +2.0 | |
| Bacitracin | BBR_RS13270 | ABC transporter ATP-binding protein | +1.6 | |
| Bacitracin | BBR_RS13275 | hypothetical protein | +1.9 | |
| Bacitracin | BBR_RS18480 | LacI family DNA-binding transcriptional regulator | -1.5 | |
| Bacitracin | BBR_RS20240 | hypothetical protein | -1.9 | |
| Benzethonium chloride | BBR_RS18130 | glucokinase | -1.8 | |
| Bicyclomycin | BBR_RS11925 | hypothetical protein | -1.2 | |
| Bicyclomycin | BBR_RS11935 | hypothetical protein | -1.2 | |
| Bicyclomycin | BBR_RS12865 | S9 family peptidase | variable | |
| Bicyclomycin | BBR_RS13430 | hypothetical protein | variable | |
| Bicyclomycin | BBR_RS13435 | hypothetical protein | +1.4 | |
| Bicyclomycin | BBR_RS13845 | dipeptidase | -1.3 | |
| Bicyclomycin | BBR_RS14485 | DUF3000 domain-containing protein | +2.2 | |
| Bicyclomycin | BBR_RS15240 | LacI family DNA-binding transcriptional regulator | +3.2 | |
| Bicyclomycin | BBR_RS17335 | DUF3516 domain-containing protein | +1.2 | |
| Bicyclomycin | BBR_RS18130 | glucokinase | +8.0 | |
| Bicyclomycin | BBR_RS18135 | hypothetical protein | variable | |
| Bicyclomycin | BBR_RS18470 | MFS transporter | +8.8 | |
| Bicyclomycin | BBR_RS18475 | DUF4981 domain-containing protein | +1.6 | |
| Bicyclomycin | BBR_RS18645 | DNA-binding response regulator | +1.5 | |
| Bicyclomycin | BBR_RS18985 | 4-alpha-glucanotransferase | +2.9 | |
| Bicyclomycin | BBR_RS20470 | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG | variable | |
| Bicyclomycin | BBR_RS20500 | hypothetical protein | variable | |
| Carbenicillin disodium salt | BBR_RS10305 | Conserved hypothetical membrane spanning protein, VanZ family | -1.1 | |
| Carbenicillin disodium salt | BBR_RS18645 | DNA-binding response regulator | +1.8 | |
| Cefsulodin sodium salt hydrate | BBR_RS19440 | polysaccharide deacetylase family protein | +1.3 | |
| Cerulenin | BBR_RS12115 | hypothetical protein | +2.1 | |
| Cerulenin | BBR_RS12860 | DUF2183 domain-containing protein | -1.6 | |
| Cerulenin | BBR_RS13435 | hypothetical protein | +1.2 | |
| Cetomacrogol 1000 | BBR_RS12115 | hypothetical protein | +8.7 | |
| Cetomacrogol 1000 | BBR_RS12860 | DUF2183 domain-containing protein | variable | |
| Cetomacrogol 1000 | BBR_RS13430 | hypothetical protein | +1.2 | |
| Cetomacrogol 1000 | BBR_RS14600 | ABC transporter ATP-binding protein | -1.2 | |
| Cetomacrogol 1000 | BBR_RS14605 | ABC transporter permease | -1.8 | |
| Cetomacrogol 1000 | BBR_RS16140 | long-chain fatty acid--CoA ligase | -2.2 | |
| Cetomacrogol 1000 | BBR_RS18130 | glucokinase | variable | |
| Cetomacrogol 1000 | BBR_RS18985 | 4-alpha-glucanotransferase | +2.0 | |
| Choline chloride | BBR_RS10715 | tRNA-guanine(34) transglycosylase | -1.1 | |
| Choline chloride | BBR_RS10765 | hypothetical protein | -1.6 | |
| Choline chloride | BBR_RS10770 | CrcB family protein | -1.8 | |
| Choline chloride | BBR_RS12325 | type 1 glutamine amidotransferase | -1.4 | |
| Choline chloride | BBR_RS12860 | DUF2183 domain-containing protein | -1.9 | |
| Choline chloride | BBR_RS13780 | ABC transporter permease | -1.4 | |
| Choline chloride | BBR_RS13785 | myristoyl transferase | -1.4 | |
| Choline chloride | BBR_RS13845 | dipeptidase | -1.9 | |
| Choline chloride | BBR_RS17995 | citrate synthase | -1.5 | |
| Ciprofloxacin Hydrochloride | BBR_RS18470 | MFS transporter | -3.2 | |
| Clotrimazole | BBR_RS12920 | glycine synthesis protein GlyXL (from data) | -1.3 | |
| D-Cycloserine | BBR_RS15220 | trimeric intracellular cation channel family protein | +1.2 | |
| D-Cycloserine | BBR_RS15560 | aminotransferase class V-fold PLP-dependent enzyme | +1.8 | Yes |
| D-Cycloserine | BBR_RS20040 | amino acid permease | -1.3 | |
| Daptomycin | BBR_RS18645 | DNA-binding response regulator | -3.8 | |
| Dimetridazole | BBR_RS10560 | hypothetical protein | -2.8 | |
| Dimetridazole | BBR_RS14030 | DNA repair protein RecN | -1.4 | |
| Dimetridazole | BBR_RS14115 | transcription-repair coupling factor | -1.1 | Yes |
| Dimetridazole | BBR_RS15510 | excinuclease ABC subunit UvrA | -1.9 | |
| Dimetridazole | BBR_RS15515 | excinuclease ABC subunit UvrC | -2.2 | |
| Dimetridazole | BBR_RS19295 | ATP-dependent DNA helicase RecG | -2.3 | |
| EDTA | BBR_RS11440 | FMN-binding protein | -1.9 | |
| EDTA | BBR_RS13355 | ABC transporter substrate-binding protein | -6.0 | |
| EDTA | BBR_RS19930 | FAD:protein FMN transferase | -1.7 | |
| Flavomycin | BBR_RS18645 | DNA-binding response regulator | +1.6 | |
| Gentamicin sulfate salt | BBR_RS16315 | hypothetical protein | +1.7 | |
| Gentamicin sulfate salt | BBR_RS18470 | MFS transporter | +1.5 | |
| Gramicidin | BBR_RS12180 | DUF2974 domain-containing protein | -2.0 | |
| Gramicidin | BBR_RS12435 | ABC transporter ATP-binding protein | -3.9 | |
| Gramicidin | BBR_RS12440 | Permease of ABC transporter system | -6.1 | |
| Gramicidin | BBR_RS12860 | DUF2183 domain-containing protein | -1.3 | |
| Gramicidin | BBR_RS14100 | UPF0182 family protein | -1.3 | |
| Gramicidin | BBR_RS14600 | ABC transporter ATP-binding protein | -1.1 | |
| Gramicidin | BBR_RS14605 | ABC transporter permease | -1.1 | |
| Gramicidin | BBR_RS16660 | ABC transporter ATP-binding protein | -1.4 | |
| Gramicidin | BBR_RS16665 | Permease of ABC transporter system | -1.5 | |
| Gramicidin | BBR_RS17960 | Ppx/GppA family phosphatase | -1.9 | |
| Gramicidin | BBR_RS18200 | hypothetical protein | -1.9 | |
| Gramicidin | BBR_RS18205 | ABC transporter ATP-binding protein | -1.9 | |
| Gramicidin | BBR_RS19715 | DUF4190 domain-containing protein | -1.2 | |
| Gramicidin | BBR_RS20695 | hypothetical protein | -5.6 | |
| Irgasan | BBR_RS12920 | glycine synthesis protein GlyXL (from data) | -1.8 | |
| Isovaleric acid | BBR_RS20215 | sodium:proton antiporter | -1.0 | |
| Kanamycin sulfate | BBR_RS10715 | tRNA-guanine(34) transglycosylase | -1.9 | |
| Kanamycin sulfate | BBR_RS13780 | ABC transporter permease | -1.7 | |
| Kanamycin sulfate | BBR_RS13785 | myristoyl transferase | -1.8 | |
| Kanamycin sulfate | BBR_RS14010 | TlyA family rRNA (cytidine-2'-O)-methyltransferase | +1.7 | |
| Kanamycin sulfate | BBR_RS14100 | UPF0182 family protein | -2.5 | |
| Kanamycin sulfate | BBR_RS14600 | ABC transporter ATP-binding protein | -1.5 | |
| Kanamycin sulfate | BBR_RS14605 | ABC transporter permease | -1.9 | |
| Kanamycin sulfate | BBR_RS16585 | BAX inhibitor (BI)-1/YccA family protein | -3.0 | |
| Kanamycin sulfate | BBR_RS17005 | methyltransferase domain-containing protein | +1.5 | |
| Kanamycin sulfate | BBR_RS19650 | NUDIX hydrolase | -1.2 | |
| Kanamycin sulfate | BBR_RS19915 | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase | -1.9 | |
| Levofloxacin | BBR_RS18470 | MFS transporter | -2.0 | |
| Lincomycin hydrochloride | BBR_RS18285 | ABC transporter ATP-binding protein | -4.5 | |
| Lincomycin hydrochloride | BBR_RS19915 | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase | -1.6 | |
| Linezolid | BBR_RS17335 | DUF3516 domain-containing protein | -1.0 | |
| Lysozyme | BBR_RS18645 | DNA-binding response regulator | -2.3 | |
| Metronidazole | BBR_RS10560 | hypothetical protein | -5.1 | |
| Metronidazole | BBR_RS14030 | DNA repair protein RecN | -1.7 | |
| Metronidazole | BBR_RS14115 | transcription-repair coupling factor | -1.6 | |
| Metronidazole | BBR_RS14535 | pyridoxal phosphate-dependent aminotransferase | +1.4 | |
| Metronidazole | BBR_RS15510 | excinuclease ABC subunit UvrA | -3.2 | |
| Metronidazole | BBR_RS15515 | excinuclease ABC subunit UvrC | -3.3 | |
| Metronidazole | BBR_RS15590 | molecular chaperone DnaJ | -2.1 | |
| Metronidazole | BBR_RS18645 | DNA-binding response regulator | +2.3 | |
| Metronidazole | BBR_RS19045 | DNA polymerase IV | -1.5 | |
| Metronidazole | BBR_RS19295 | ATP-dependent DNA helicase RecG | -3.4 | |
| Moxifloxacin | BBR_RS11670 | DNA recombination protein RmuC | -1.3 | |
| Moxifloxacin | BBR_RS14030 | DNA repair protein RecN | -2.9 | |
| Moxifloxacin | BBR_RS14115 | transcription-repair coupling factor | -1.1 | Yes |
| Moxifloxacin | BBR_RS17985 | helicase | -4.7 | |
| Moxifloxacin | BBR_RS18740 | DNA repair protein RadA | -2.2 | |
| Moxifloxacin | BBR_RS19295 | ATP-dependent DNA helicase RecG | -1.9 | |
| Neomycin trisulfate salt hydrate | BBR_RS10715 | tRNA-guanine(34) transglycosylase | -1.0 | |
| Neomycin trisulfate salt hydrate | BBR_RS14100 | UPF0182 family protein | -1.9 | |
| Neomycin trisulfate salt hydrate | BBR_RS14600 | ABC transporter ATP-binding protein | -1.4 | |
| Neomycin trisulfate salt hydrate | BBR_RS14605 | ABC transporter permease | -1.8 | |
| Neomycin trisulfate salt hydrate | BBR_RS16585 | BAX inhibitor (BI)-1/YccA family protein | -2.2 | |
| Nisin from Lactococcus lactis | BBR_RS10765 | hypothetical protein | +1.4 | |
| Nisin from Lactococcus lactis | BBR_RS10770 | CrcB family protein | +1.5 | |
| Nisin from Lactococcus lactis | BBR_RS15970 | hypothetical protein | -6.1 | |
| Nisin from Lactococcus lactis | BBR_RS15975 | hypothetical protein | -6.9 | |
| Nisin from Lactococcus lactis | BBR_RS15980 | Lantibiotic transport ATP-binding protein | -6.1 | |
| Nisin from Lactococcus lactis | BBR_RS19440 | polysaccharide deacetylase family protein | variable | |
| Nitrofurantoin | BBR_RS10560 | hypothetical protein | -4.9 | |
| Nitrofurantoin | BBR_RS11200 | LacI family transcriptional regulator | -1.1 | |
| Nitrofurantoin | BBR_RS13195 | pyridoxal 5'-phosphate synthase lyase subunit PdxS | +1.4 | |
| Nitrofurantoin | BBR_RS14115 | transcription-repair coupling factor | -2.5 | |
| Nitrofurantoin | BBR_RS14535 | pyridoxal phosphate-dependent aminotransferase | +1.2 | |
| Nitrofurantoin | BBR_RS15510 | excinuclease ABC subunit UvrA | -5.0 | Yes |
| Nitrofurantoin | BBR_RS15515 | excinuclease ABC subunit UvrC | -4.9 | |
| Nitrofurantoin | BBR_RS15590 | molecular chaperone DnaJ | -1.8 | |
| Nitrofurantoin | BBR_RS19295 | ATP-dependent DNA helicase RecG | -2.8 | |
| Nitrofurantoin | BBR_RS20090 | DUF4235 domain-containing protein | +1.3 | |
| Nitrofurantoin | BBR_RS20105 | YhgE/Pip domain-containing protein | -1.2 | |
| Nitrofurazone | BBR_RS10560 | hypothetical protein | -3.1 | |
| Nitrofurazone | BBR_RS14115 | transcription-repair coupling factor | -1.2 | |
| Nitrofurazone | BBR_RS15510 | excinuclease ABC subunit UvrA | -4.9 | |
| Nitrofurazone | BBR_RS15515 | excinuclease ABC subunit UvrC | -4.5 | |
| Nitrofurazone | BBR_RS19295 | ATP-dependent DNA helicase RecG | -1.5 | |
| Novobiocin sodium salt | BBR_RS16745 | segregation/condensation protein A | -1.1 | |
| Penicillin g | BBR_RS10305 | Conserved hypothetical membrane spanning protein, VanZ family | -1.3 | |
| Penicillin g | BBR_RS10725 | Lead, cadmium, zinc and mercury transporting ATPase | +1.3 | |
| Penicillin g | BBR_RS11445 | TetR/AcrR family transcriptional regulator | -1.5 | |
| Penicillin g | BBR_RS17475 | cold-shock protein | +1.4 | |
| Penicillin g | BBR_RS18640 | PspC domain-containing protein | +1.6 | |
| Penicillin g | BBR_RS18645 | DNA-binding response regulator | +2.0 | |
| Penicillin g | BBR_RS19440 | polysaccharide deacetylase family protein | +1.1 | |
| Phosphomycin disodium salt | BBR_RS18470 | MFS transporter | -1.8 | |
| Potassium acetate | BBR_RS10715 | tRNA-guanine(34) transglycosylase | -1.0 | |
| Potassium acetate | BBR_RS12055 | thioredoxin | -1.6 | |
| Potassium acetate | BBR_RS12115 | hypothetical protein | +4.4 | |
| Potassium acetate | BBR_RS12180 | DUF2974 domain-containing protein | +2.6 | |
| Potassium acetate | BBR_RS13430 | hypothetical protein | +3.2 | |
| Potassium acetate | BBR_RS13435 | hypothetical protein | +3.0 | |
| Potassium acetate | BBR_RS13845 | dipeptidase | -1.4 | |
| Potassium acetate | BBR_RS16495 | serine/threonine-protein kinase | variable | |
| Potassium acetate | BBR_RS18130 | glucokinase | +2.9 | |
| Potassium acetate | BBR_RS18985 | 4-alpha-glucanotransferase | +2.6 | |
| Potassium iodide | BBR_RS12860 | DUF2183 domain-containing protein | -1.4 | |
| Pyrimethamine | BBR_RS15410 | methylenetetrahydrofolate reductase [NAD(P)H] | +1.1 | |
| Ramoplanin | BBR_RS19515 | ABC transporter ATP-binding protein | -1.2 | |
| Rifampicin | BBR_RS18470 | MFS transporter | +1.8 | |
| Serine hydroxamate | BBR_RS13195 | pyridoxal 5'-phosphate synthase lyase subunit PdxS | -1.4 | |
| Serine hydroxamate | BBR_RS13200 | pyridoxal 5'-phosphate synthase glutaminase subunit PdxT | -1.6 | |
| Serine hydroxamate | BBR_RS13205 | PLP-dependent aminotransferase family protein | -1.9 | |
| Serine hydroxamate | BBR_RS20040 | amino acid permease | -1.8 | |
| Sodium Chloride | BBR_RS10715 | tRNA-guanine(34) transglycosylase | -1.1 | |
| Sodium Chloride | BBR_RS12860 | DUF2183 domain-containing protein | -2.3 | |
| Sodium D,L-Lactate | BBR_RS12115 | hypothetical protein | +1.4 | |
| Sodium D,L-Lactate | BBR_RS13430 | hypothetical protein | +1.4 | |
| Sodium D,L-Lactate | BBR_RS13435 | hypothetical protein | +1.6 | |
| Sodium D,L-Lactate | BBR_RS16105 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | -2.0 | |
| Sodium D,L-Lactate | BBR_RS20215 | sodium:proton antiporter | -3.5 | |
| Sodium nitrite | BBR_RS14115 | transcription-repair coupling factor | -1.5 | |
| Sodium nitrite | BBR_RS16215 | restriction enzyme | +1.5 | |
| Spiramycin | BBR_RS16105 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | +2.4 | Yes |
| Spiramycin | BBR_RS19915 | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase | -1.4 | |
| Streptomycin sulfate salt | BBR_RS10715 | tRNA-guanine(34) transglycosylase | -2.1 | |
| Streptomycin sulfate salt | BBR_RS10765 | hypothetical protein | +1.2 | |
| Streptomycin sulfate salt | BBR_RS10770 | CrcB family protein | +1.6 | |
| Streptomycin sulfate salt | BBR_RS11520 | P-II family nitrogen regulator | +1.4 | |
| Streptomycin sulfate salt | BBR_RS12055 | thioredoxin | +4.5 | |
| Streptomycin sulfate salt | BBR_RS12115 | hypothetical protein | +1.9 | |
| Streptomycin sulfate salt | BBR_RS12850 | NAD(+) diphosphatase | +1.1 | |
| Streptomycin sulfate salt | BBR_RS13780 | ABC transporter permease | -3.4 | |
| Streptomycin sulfate salt | BBR_RS13785 | myristoyl transferase | -2.1 | |
| Streptomycin sulfate salt | BBR_RS14010 | TlyA family rRNA (cytidine-2'-O)-methyltransferase | +2.2 | Yes |
| Streptomycin sulfate salt | BBR_RS14100 | UPF0182 family protein | -2.0 | |
| Streptomycin sulfate salt | BBR_RS14605 | ABC transporter permease | -1.5 | |
| Streptomycin sulfate salt | BBR_RS14860 | MFS transporter | +4.9 | |
| Streptomycin sulfate salt | BBR_RS16140 | long-chain fatty acid--CoA ligase | -1.6 | |
| Streptomycin sulfate salt | BBR_RS16585 | BAX inhibitor (BI)-1/YccA family protein | -2.0 | |
| Streptomycin sulfate salt | BBR_RS17005 | methyltransferase domain-containing protein | +2.9 | |
| Streptomycin sulfate salt | BBR_RS18130 | glucokinase | +1.4 | |
| Streptomycin sulfate salt | BBR_RS18470 | MFS transporter | +1.7 | |
| Streptomycin sulfate salt | BBR_RS18750 | pseudouridine synthase | +2.1 | |
| Streptomycin sulfate salt | BBR_RS19685 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | +1.7 | |
| Streptomycin sulfate salt | BBR_RS19695 | tRNA glutamyl-Q(34) synthetase GluQRS | -1.3 | |
| Streptomycin sulfate salt | BBR_RS20090 | DUF4235 domain-containing protein | +1.1 | |
| Streptomycin sulfate salt | BBR_RS20470 | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG | +5.9 | |
| Sulfamethizole | BBR_RS15405 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase | -1.2 | |
| Sulfamethizole | BBR_RS17315 | MFS transporter | +1.1 | |
| Sulfamonomethoxine | BBR_RS15405 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase | -1.2 | |
| Sulfamonomethoxine | BBR_RS17315 | MFS transporter | +1.0 | |
| Tiamulin | BBR_RS10725 | Lead, cadmium, zinc and mercury transporting ATPase | -1.2 | |
| Tiamulin | BBR_RS18285 | ABC transporter ATP-binding protein | -6.2 | |
| Tiamulin | BBR_RS18470 | MFS transporter | +1.5 | |
| Tiamulin | BBR_RS18985 | 4-alpha-glucanotransferase | +1.4 | |
| Tiamulin | BBR_RS19915 | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase | -1.6 | |
| Ticarcillin disodium salt | BBR_RS10305 | Conserved hypothetical membrane spanning protein, VanZ family | -1.4 | |
| Ticarcillin disodium salt | BBR_RS10725 | Lead, cadmium, zinc and mercury transporting ATPase | +1.5 | |
| Ticarcillin disodium salt | BBR_RS11635 | hypothetical protein | -1.3 | |
| Ticarcillin disodium salt | BBR_RS16740 | SMC-Scp complex subunit ScpB | -1.3 | |
| Ticarcillin disodium salt | BBR_RS17475 | cold-shock protein | +2.0 | |
| Ticarcillin disodium salt | BBR_RS18640 | PspC domain-containing protein | +2.0 | |
| Ticarcillin disodium salt | BBR_RS18645 | DNA-binding response regulator | +2.4 | |
| Ticarcillin disodium salt | BBR_RS19440 | polysaccharide deacetylase family protein | +1.1 | |
| Trimethoprim | BBR_RS15410 | methylenetetrahydrofolate reductase [NAD(P)H] | +1.4 | |
| Trimethoprim | BBR_RS15640 | HIT domain-containing protein | +1.8 | |
| Trimethoprim | BBR_RS20240 | hypothetical protein | +1.3 | |
| Vancomycin Hydrochloride from Streptomyces orientalis | BBR_RS18645 | DNA-binding response regulator | -2.5 | |
| Warfarin | BBR_RS12860 | DUF2183 domain-containing protein | -3.8 | |
| Warfarin | BBR_RS16140 | long-chain fatty acid--CoA ligase | -2.8 | |