Private Fitness
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Specific Phenotypes for
Escherichia coli Nissle 1917
in phage experiments
Condition
Gene
Description
Fitness
Cons.
MOI 10
ECOLIN
_RS00590
1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD
+1.5
MOI 10
ECOLIN
_RS02345
pyrroline-5-carboxylate reductase
-2.2
MOI 10
ECOLIN
_RS02490
nucleoside-specific channel-forming protein Tsx
+1.4
MOI 10
ECOLIN
_RS02575
heme o synthase
-1.9
MOI 10
ECOLIN
_RS02590
cytochrome o ubiquinol oxidase subunit I
-1.7
MOI 10
ECOLIN
_RS03400
transcription antiterminator/RNA stability regulator CspE
variable
MOI 10
ECOLIN
_RS03730
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
-1.4
MOI 10
ECOLIN
_RS06225
flagellar hook assembly protein FlgD
+1.7
MOI 10
ECOLIN
_RS06335
cell division protein YceG
+2.7
MOI 10
ECOLIN
_RS12720
bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase
-1.6
MOI 10
ECOLIN
_RS12935
porin OmpC
+2.6
MOI 10
ECOLIN
_RS13160
signal transduction protein PmrD
variable
MOI 10
ECOLIN
_RS14140
outer membrane protein assembly factor BamC
+2.3
Yes
MOI 10
ECOLIN
_RS14185
uracil phosphoribosyltransferase
+1.3
MOI 10
ECOLIN
_RS14370
Fe-S cluster assembly transcriptional regulator IscR
+1.4
MOI 10
ECOLIN
_RS14935
glycine betaine/L-proline ABC transporter permease ProW
variable
Yes
MOI 10
ECOLIN
_RS14940
glycine betaine/L-proline ABC transporter substrate-binding protein ProX
variable
MOI 10
ECOLIN
_RS15875
phosphoenolpyruvate--protein phosphotransferase
+1.4
MOI 10
ECOLIN
_RS16115
single-stranded-DNA-specific exonuclease RecJ
-1.1
MOI 10
ECOLIN
_RS17845
DedA family general envelope maintenance protein YqjA
-1.7
Yes
MOI 10
ECOLIN
_RS18185
tRNA pseudouridine(55) synthase TruB
variable
Yes
MOI 10
ECOLIN
_RS18365
BolA family iron metabolism protein IbaG
-1.4
MOI 10
ECOLIN
_RS19465
Tex family protein
variable
MOI 10
ECOLIN
_RS19515
maltodextrin phosphorylase
variable
Yes
MOI 10
ECOLIN
_RS19520
HTH-type transcriptional regulator MalT
variable
Yes
MOI 10
ECOLIN
_RS20295
kdo(2)-lipid A phosphoethanolamine 7''-transferase
+1.9
Yes
MOI 10
ECOLIN
_RS21595
FadR/GntR family transcriptional regulator
-1.2
MOI 10
ECOLIN
_RS21885
DNA helicase II
-1.7
MOI 10
ECOLIN
_RS23305
maltoporin LamB
+1.4
Yes
MOI 10
ECOLIN
_RS24520
gamma-glutamylcyclotransferase
+1.6