Specific Phenotypes for Bifidobacterium breve UCC2003 in nutrient dropout experiments

Condition Gene Description Fitness Cons.
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS10595 glutamine amidotransferase -2.8  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS10800 ketol-acid reductoisomerase -4.0  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS10830 ketol-acid reductoisomerase -4.5  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS12055 thioredoxin -1.5  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS12285 nucleoside hydrolase -1.2  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS12325 type 1 glutamine amidotransferase +1.3  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS12345 acetolactate synthase small subunit -4.1  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS12350 acetolactate synthase large subunit -5.5  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS12410 non-canonical purine NTP pyrophosphatase -1.3  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS12860 DUF2183 domain-containing protein -1.8  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS12870 3-isopropylmalate dehydrogenase +2.4  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS13140 cysteine synthase +1.6  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS13855 ABC transporter ATP-binding protein -2.0  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS13860 energy-coupling factor transporter transmembrane protein EcfT -2.3  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS13915 argininosuccinate synthase -3.2  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS14865 haloacid dehalogenase-like hydrolase +2.0  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15185 NAD(P) transhydrogenase subunit alpha -1.2  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15190 NAD(P) transhydrogenase subunit alpha -1.6  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15195 NAD(P) transhydrogenase subunit beta -1.0  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15255 glutamate synthase large subunit -1.0  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15410 methylenetetrahydrofolate reductase [NAD(P)H] +5.4  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15475 Histidinol-phosphatase (EC 3.1.3.15) (from data) -5.6  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15560 aminotransferase class V-fold PLP-dependent enzyme -4.5  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15570 branched-chain amino acid transport system II carrier protein -1.3  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15795 phosphoribosyl-ATP diphosphatase -5.0  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15810 tryptophan synthase subunit alpha -5.4  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS15815 tryptophan synthase subunit beta -5.8  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS16085 anthranilate synthase component I -3.0  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS16090 phosphoribosyl-AMP cyclohydrolase -5.3  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS16095 imidazole glycerol phosphate synthase subunit HisF -5.4  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS16510 anthranilate phosphoribosyltransferase -5.8  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS16680 prephenate dehydratase (EC 4.2.1.51) (from data) -5.6  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS17030 bifunctional 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase/phosphoribosylanthranilate isomerase PriA -5.2  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS17035 imidazole glycerol phosphate synthase subunit HisH -5.5  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS17045 imidazoleglycerol-phosphate dehydratase -4.8  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS17050 histidinol-phosphate transaminase -5.1  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS17055 histidinol dehydrogenase -5.8  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS17475 cold-shock protein +1.3  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS17485 uracil-DNA glycosylase -1.8  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS17530 Permease of ABC transporter system -2.2  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS17635 dihydroxy-acid dehydratase -5.5  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS18160 DUF3180 domain-containing protein -1.3  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS19060 amino acid permease +1.2  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS19630 3-isopropylmalate dehydratase large subunit +2.9  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS20260 PTS N-acetylglucosamine transporter subunit IIABC variable  
aa Glycine Leucine Cysteine Methionine Glutamate BBR_RS21120 hypothetical protein -1.4  
no Adenine BBR_RS11620 Two-component sensor protein -1.1  
no Adenine BBR_RS12055 thioredoxin -1.5  
no Adenine BBR_RS12440 Permease of ABC transporter system -1.1  
no Adenine BBR_RS13850 ABC transporter permease +1.5  
no Adenine BBR_RS14005 haloacid dehalogenase -1.6  
no Adenine BBR_RS14570 ATP-binding protein -1.4  
no Adenine BBR_RS16055 amino acid permease -2.0  
no Adenine BBR_RS16290 histidine phosphatase family protein -1.3  
no Adenine BBR_RS16495 serine/threonine-protein kinase -1.4  
no Adenine BBR_RS17315 MFS transporter -2.0  
no Adenine BBR_RS18335 hypothetical protein -1.4  
no Adenine BBR_RS19145 NCS2 family permease +2.0  
no Adenine BBR_RS19275 laccase domain-containing protein variable  
no Adenine BBR_RS19730 hypothetical protein -1.4  
no Adenine BBR_RS20260 PTS N-acetylglucosamine transporter subunit IIABC variable  
no Adenine BBR_RS20525 DUF3800 domain-containing protein -2.2  
no Alanine BBR_RS15365 alpha/beta hydrolase -1.5  
no Alanine BBR_RS15560 aminotransferase class V-fold PLP-dependent enzyme -4.4  
no Arginine BBR_RS13915 argininosuccinate synthase -5.6  
no Asparagine BBR_RS12055 thioredoxin -1.7  
no Asparagine BBR_RS12860 DUF2183 domain-containing protein -1.3  
no Asparagine BBR_RS18335 hypothetical protein -1.4  
no Asparagine BBR_RS20260 PTS N-acetylglucosamine transporter subunit IIABC -1.2  
no Aspartate BBR_RS12285 nucleoside hydrolase -1.1  
no Biotin BBR_RS16055 amino acid permease -1.3  
no Biotin BBR_RS20525 DUF3800 domain-containing protein -1.6  
no Cysteine BBR_RS11290 DUF1275 domain-containing protein +1.4  
no Cysteine BBR_RS12115 hypothetical protein +1.4  
no Cysteine BBR_RS13140 cysteine synthase -2.0  
no Cysteine BBR_RS13145 cystathionine gamma-synthase -1.8  
no Cysteine BBR_RS13155 S-ribosylhomocysteine lyase -1.4  
no Cysteine BBR_RS14455 ABC transporter permease +1.2  
no Cysteine BBR_RS14595 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase -1.1  
no Cysteine BBR_RS14630 glutamine-binding protein glnH -1.9  
no Cysteine BBR_RS18230 SAM-dependent methyltransferase -1.5  
no Cysteine BBR_RS18330 PIN domain-containing protein +1.9  
no Cysteine BBR_RS19845 ABC transporter ATP-binding protein -1.0  
no Cysteine BBR_RS19850 ABC transporter ATP-binding protein -1.2  
no FolicAcid BBR_RS14005 haloacid dehalogenase -1.8  
no Glutamate BBR_RS10310 NADP-specific glutamate dehydrogenase +1.9  
no Glutamate BBR_RS12125 transposase +1.7  
no Glutamate BBR_RS12870 3-isopropylmalate dehydrogenase +2.1  
no Glutamate BBR_RS13110 type III pantothenate kinase +1.3  
no Glutamate BBR_RS17995 citrate synthase -1.2  
no Glutamate BBR_RS19630 3-isopropylmalate dehydratase large subunit +2.7  
no Glycine BBR_RS10765 hypothetical protein -1.3  
no Glycine BBR_RS12115 hypothetical protein -2.1  
no Glycine BBR_RS12350 acetolactate synthase large subunit -1.6  
no Glycine BBR_RS12920 glycine synthesis protein GlyXL (from data) -5.4  
no Glycine BBR_RS14535 pyridoxal phosphate-dependent aminotransferase -5.1  
no Glycine BBR_RS14860 MFS transporter +1.1  
no Glycine BBR_RS15420 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase +1.9  
no Glycine BBR_RS17005 methyltransferase domain-containing protein +1.8  
no Glycine BBR_RS18495 ROK family protein +1.4  
no Glycine BBR_RS18560 hypothetical protein -2.1  
no Glycine BBR_RS18770 hypothetical protein +1.2  
no Glycine BBR_RS20260 PTS N-acetylglucosamine transporter subunit IIABC variable  
no Glycine BBR_RS20470 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG +1.1  
no Guanine BBR_RS16055 amino acid permease -1.3  
no Histidine BBR_RS14770 hypothetical protein -1.5  
no Histidine BBR_RS15475 Histidinol-phosphatase (EC 3.1.3.15) (from data) -6.5  
no Histidine BBR_RS16090 phosphoribosyl-AMP cyclohydrolase -5.7  
no Histidine BBR_RS16095 imidazole glycerol phosphate synthase subunit HisF -6.0  
no Histidine BBR_RS17030 bifunctional 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase/phosphoribosylanthranilate isomerase PriA -6.1  
no Histidine BBR_RS17035 imidazole glycerol phosphate synthase subunit HisH -5.8  
no Histidine BBR_RS17045 imidazoleglycerol-phosphate dehydratase -5.6  
no Histidine BBR_RS17050 histidinol-phosphate transaminase -6.3  
no Histidine BBR_RS17055 histidinol dehydrogenase -5.8  
no Isoleucine BBR_RS12350 acetolactate synthase large subunit -3.4  
no Isoleucine BBR_RS17060 acylphosphatase -1.3  
no Isoleucine BBR_RS17635 dihydroxy-acid dehydratase -2.6  
no Isoleucine BBR_RS20130 threonine ammonia-lyase -1.2  
no Isoleucine BBR_RS20380 XRE family transcriptional regulator -1.5  
no Leucine BBR_RS10830 ketol-acid reductoisomerase -1.1  
no Leucine BBR_RS11170 2-isopropylmalate synthase -4.7  
no Leucine BBR_RS12350 acetolactate synthase large subunit -2.3  
no Leucine BBR_RS12870 3-isopropylmalate dehydrogenase -3.4  
no Leucine BBR_RS15485 ABC transporter ATP-binding protein -1.9  
no Leucine BBR_RS15570 branched-chain amino acid transport system II carrier protein -4.3  
no Leucine BBR_RS17635 dihydroxy-acid dehydratase -2.3  
no Leucine BBR_RS19630 3-isopropylmalate dehydratase large subunit -3.0  
no LipoicAcid BBR_RS14770 hypothetical protein -1.9  
no Lysine BBR_RS12350 acetolactate synthase large subunit -1.1  
no Lysine BBR_RS12990 4-hydroxy-tetrahydrodipicolinate reductase -2.6  
no Lysine BBR_RS15590 molecular chaperone DnaJ -1.6  
no Lysine BBR_RS17930 flavodoxin family protein -2.5  
no Lysine BBR_RS18750 pseudouridine synthase -1.4  
no Methionine BBR_RS12115 hypothetical protein +1.4  
no Methionine BBR_RS12350 acetolactate synthase large subunit -1.4  
no Methionine BBR_RS12990 4-hydroxy-tetrahydrodipicolinate reductase -1.6  
no Methionine BBR_RS13110 type III pantothenate kinase +1.9  
no Methionine BBR_RS13150 DNA helicase RecQ +1.0  
no Methionine BBR_RS13355 ABC transporter substrate-binding protein +2.0  
no Methionine BBR_RS14595 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase +1.2  
no Methionine BBR_RS15405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -3.1  
no Methionine BBR_RS15410 methylenetetrahydrofolate reductase [NAD(P)H] -3.1  
no Methionine BBR_RS15470 LysR family transcriptional regulator -2.5  
no Methionine BBR_RS15590 molecular chaperone DnaJ -1.7  
no Nicotinate BBR_RS12350 acetolactate synthase large subunit -1.2  
no Nicotinate BBR_RS12990 4-hydroxy-tetrahydrodipicolinate reductase -1.3  
no Nicotinate BBR_RS16720 nicotinate-nucleotide diphosphorylase (carboxylating) -4.5  
no Nicotinate BBR_RS16730 quinolinate synthase NadA -4.8  
no Pantothenate BBR_RS18655 aminoglycoside phosphotransferase family protein +1.0  
no Phenylalanine BBR_RS10310 NADP-specific glutamate dehydrogenase +1.4  
no Phenylalanine BBR_RS12055 thioredoxin -1.9  
no Phenylalanine BBR_RS12860 DUF2183 domain-containing protein -1.7  
no Phenylalanine BBR_RS13585 transporter -3.2  
no Phenylalanine BBR_RS14115 transcription-repair coupling factor +1.1  
no Phenylalanine BBR_RS15100 murein L,D-transpeptidase +1.8  
no Phenylalanine BBR_RS15420 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase -2.1  
no Phenylalanine BBR_RS16680 prephenate dehydratase (EC 4.2.1.51) (from data) -5.5  
no Phenylalanine BBR_RS17475 cold-shock protein +1.6  
no Phenylalanine BBR_RS18470 MFS transporter +1.5  
no Phenylalanine BBR_RS18625 alpha/beta hydrolase +3.7  
no Phenylalanine BBR_RS18640 PspC domain-containing protein +1.3  
no Phenylalanine BBR_RS19060 amino acid permease +5.2  
no Phenylalanine BBR_RS19195 3-deoxy-7-phosphoheptulonate synthase -5.5  
no Phenylalanine BBR_RS19275 laccase domain-containing protein +1.3  
no Phenylalanine BBR_RS19630 3-isopropylmalate dehydratase large subunit +1.6  
no Phenylalanine BBR_RS19650 NUDIX hydrolase -1.1  
no Phenylalanine BBR_RS19845 ABC transporter ATP-binding protein -1.1  
no Phenylalanine BBR_RS19915 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -2.0  
no Phenylalanine BBR_RS20090 DUF4235 domain-containing protein +1.4  
no Phenylalanine BBR_RS20260 PTS N-acetylglucosamine transporter subunit IIABC variable  
no Pyridoxamine BBR_RS13195 pyridoxal 5'-phosphate synthase lyase subunit PdxS -5.3  
no Pyridoxamine BBR_RS13200 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT -2.7  
no Pyridoxamine BBR_RS13205 PLP-dependent aminotransferase family protein -5.9  
no Pyridoxamine BBR_RS16055 amino acid permease -1.7  
no Riboflavin BBR_RS12990 4-hydroxy-tetrahydrodipicolinate reductase -1.7  
no Serine BBR_RS12055 thioredoxin -1.8  
no Serine BBR_RS15420 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase -1.2  
no Serine BBR_RS19275 laccase domain-containing protein +1.0  
no Serine BBR_RS19630 3-isopropylmalate dehydratase large subunit +1.4  
no Thiamine BBR_RS16280 solute binding protein of ABC transporter system +1.1  
no Thiamine BBR_RS17200 hydroxyethylthiazole kinase -1.1  
no Thiamine BBR_RS17215 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -1.9  
no Tryptophan BBR_RS10595 glutamine amidotransferase -2.7  
no Tryptophan BBR_RS12870 3-isopropylmalate dehydrogenase +1.4  
no Tryptophan BBR_RS15810 tryptophan synthase subunit alpha -5.6  
no Tryptophan BBR_RS15815 tryptophan synthase subunit beta -5.8  
no Tryptophan BBR_RS16085 anthranilate synthase component I -4.0  
no Tryptophan BBR_RS16510 anthranilate phosphoribosyltransferase -6.3  
no Tryptophan BBR_RS17030 bifunctional 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase/phosphoribosylanthranilate isomerase PriA -5.6  
no Tyrosine BBR_RS16055 amino acid permease -1.4  
no Uracil BBR_RS14760 hypothetical protein -1.0  
no Uracil BBR_RS16055 amino acid permease -2.1  
no Valine BBR_RS10800 ketol-acid reductoisomerase -5.8  
no Valine BBR_RS10830 ketol-acid reductoisomerase -5.8  
no Valine BBR_RS12345 acetolactate synthase small subunit -5.8  
no Valine BBR_RS12350 acetolactate synthase large subunit -6.5  
no Valine BBR_RS12870 3-isopropylmalate dehydrogenase +1.4  
no Valine BBR_RS13855 ABC transporter ATP-binding protein -2.6  
no Valine BBR_RS13860 energy-coupling factor transporter transmembrane protein EcfT -2.1  
no Valine BBR_RS15405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -1.4  
no Valine BBR_RS17485 uracil-DNA glycosylase -1.1  
no Valine BBR_RS17530 Permease of ABC transporter system -2.0  
no Valine BBR_RS17635 dihydroxy-acid dehydratase -6.0  
no Valine BBR_RS19630 3-isopropylmalate dehydratase large subunit +1.5