| Condition | Gene | Description | Fitness | Cons. |
|---|
| Adenine hydrochloride hydrate | Psest_1196 | Predicted membrane protein | -1.1 | Yes |
| Adenine hydrochloride hydrate | Psest_1197 | Ureidoglycolate hydrolase | -1.8 | Yes |
| Adenine hydrochloride hydrate | Psest_1199 | OHCU decarboxylase | -6.7 | Yes |
| Adenine hydrochloride hydrate | Psest_1200 | putative urate catabolism protein | -4.3 | Yes |
| Adenine hydrochloride hydrate | Psest_1201 | hydroxyisourate hydrolase | -5.2 | Yes |
| Adenine hydrochloride hydrate | Psest_1488 | outer membrane porin, OprD family. | -1.8 | |
| Adenine hydrochloride hydrate | Psest_2079 | Predicted permeases | -1.8 | |
| Adenine hydrochloride hydrate | Psest_2539 | adenine phosphoribosyltransferase | +1.9 | |
| Adenine hydrochloride hydrate | Psest_0545 | urease accessory protein UreG | -1.8 | Yes |
| Adenine hydrochloride hydrate | Psest_0546 | hypothetical protein | -1.3 | |
| Adenine hydrochloride hydrate | Psest_0548 | Urease accessory protein UreE | -1.8 | Yes |
| Adenine hydrochloride hydrate | Psest_0557 | Urease (EC 3.5.1.5) (from data) | -1.6 | Yes |
| Adenine hydrochloride hydrate | Psest_0560 | Urease (EC 3.5.1.5) (from data) | -1.5 | |
| Adenine hydrochloride hydrate | Psest_0561 | Urease accessory protein UreH | -1.6 | Yes |
| Cytosine | Psest_2641 | Conserved secreted protein | -1.6 | |
| Cytosine | Psest_3771 | probable ammonium transporter, marine subtype | -2.3 | |
| Cytosine | Psest_0773 | Cytosine deaminase and related metal-dependent hydrolases | -4.2 | Yes |
| Cytosine | Psest_0774 | cytosine permease (from data) | -3.6 | Yes |
| D-Alanine | Psest_2134 | amino acid carrier protein | -3.2 | |
| D-Alanine | Psest_3793 | D-alanine dehydrogenase (EC 1.4.99.-) (from data) | -6.2 | Yes |
| D-Alanine | Psest_3794 | Transcriptional regulators | -6.0 | Yes |
| Glycine | Psest_0111 | Glycine/D-amino acid oxidases (deaminating) | -4.2 | Yes |
| Glycine | Psest_1180 | hydroxypyruvate isomerase | -2.5 | |
| Glycine | Psest_1636 | putative transporter, required for glycine utilization (from data) | -6.4 | Yes |
| Glycine | Psest_2134 | amino acid carrier protein | -1.6 | |
| Glycine | Psest_2849 | Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit | -1.1 | |
| Glycine | Psest_3139 | Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily | -3.0 | |
| Glycine | Psest_4076 | hypothetical protein | +1.7 | |
| L-Alanine | Psest_1464 | Selenocysteine lyase | -2.2 | |
| L-Alanine | Psest_1619 | Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 | -2.1 | |
| L-Alanine | Psest_1955 | Predicted membrane protein | -1.4 | |
| L-Alanine | Psest_1989 | Transcriptional regulators | +1.7 | |
| L-Alanine | Psest_3302 | Predicted membrane protein | -2.2 | |
| L-Alanine | Psest_3354 | 1-phosphofructokinase (EC 2.7.1.56) (from data) | +1.4 | |
| L-Alanine | Psest_3366 | Biosynthetic arginine decarboxylase (EC 4.1.1.19) (from data) | +1.0 | |
| L-Alanine | Psest_3438 | Glutamate dehydrogenase/leucine dehydrogenase | -1.6 | |
| L-Alanine | Psest_3793 | D-alanine dehydrogenase (EC 1.4.99.-) (from data) | -6.5 | Yes |
| L-Alanine | Psest_3794 | Transcriptional regulators | -7.2 | Yes |
| L-Alanine | Psest_4076 | hypothetical protein | +2.2 | |
| L-Alanine | Psest_4110 | Deoxycytidylate deaminase | +1.5 | |
| L-Alanine | Psest_4281 | ABC-type spermidine/putrescine transport system, permease component I | -1.7 | |
| L-Alanine | Psest_4282 | spermidine/putrescine ABC transporter ATP-binding subunit | -1.6 | |
| L-Alanine | Psest_4284 | Spermidine/putrescine-binding periplasmic protein | -1.3 | |
| L-Arginine | Psest_2349 | urea carboxylase-associated protein 1 | -2.3 | |
| L-Arginine | Psest_2351 | urea carboxylase | -2.4 | |
| L-Arginine | Psest_2352 | allophanate hydrolase | -1.3 | |
| L-Arginine | Psest_2355 | ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components | -2.7 | |
| L-Arginine | Psest_2356 | Fatty acid desaturase | -2.7 | |
| L-Arginine | Psest_3366 | Biosynthetic arginine decarboxylase (EC 4.1.1.19) (from data) | -1.0 | |
| L-Arginine | Psest_4288 | Glutamate--putrescine ligase (EC 6.3.1.11) (from data) | -2.6 | Yes |
| L-Citrulline | Psest_2349 | urea carboxylase-associated protein 1 | -1.6 | |
| L-Citrulline | Psest_2351 | urea carboxylase | -1.8 | |
| L-Citrulline | Psest_2355 | ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components | -1.9 | |
| L-Citrulline | Psest_2356 | Fatty acid desaturase | -1.9 | |
| L-Citrulline | Psest_3366 | Biosynthetic arginine decarboxylase (EC 4.1.1.19) (from data) | -1.2 | |
| L-Citrulline | Psest_4288 | Glutamate--putrescine ligase (EC 6.3.1.11) (from data) | -2.7 | |
| L-Citrulline | Psest_1006 | dTDP-4-dehydrorhamnose reductase | -2.0 | |
| L-Glutamic acid monopotassium salt monohydrate | Psest_0197 | TRAP transporter, 4TM/12TM fusion protein | -1.6 | Yes |
| L-Glutamic acid monopotassium salt monohydrate | Psest_0198 | TRAP transporter solute receptor, TAXI family | -1.7 | |
| L-Glutamic acid monopotassium salt monohydrate | Psest_3161 | amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family | -1.3 | Yes |
| L-Glutamic acid monopotassium salt monohydrate | Psest_3162 | amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family | -1.5 | Yes |
| L-Glutamic acid monopotassium salt monohydrate | Psest_3163 | ABC-type amino acid transport/signal transduction systems, periplasmic component/domain | -1.6 | Yes |
| L-Glutamic acid monopotassium salt monohydrate | Psest_3192 | diguanylate cyclase (GGDEF) domain | +1.5 | |
| L-Glutamic acid monopotassium salt monohydrate | Psest_4076 | hypothetical protein | +1.7 | |
| L-Glutamine | Psest_3161 | amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family | -1.6 | |
| L-Glutamine | Psest_3162 | amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family | -1.3 | |
| L-Glutamine | Psest_3163 | ABC-type amino acid transport/signal transduction systems, periplasmic component/domain | -1.2 | Yes |
| L-Glutamine | Psest_3375 | prepilin-type N-terminal cleavage/methylation domain | -1.5 | |
| L-Glutamine | Psest_4076 | hypothetical protein | +2.1 | |
| L-Glutamine | Psest_4081 | Glutaminase (EC 3.5.1.2) (from data) | -4.6 | Yes |
| L-Isoleucine | Psest_1123 | adhesin-associated sorting protein (DUF1329) (from data) | +1.3 | |
| L-Isoleucine | Psest_1187 | exodeoxyribonuclease III | +1.7 | |
| L-Isoleucine | Psest_1309 | ABC-type branched-chain amino acid transport systems, ATPase component | -1.3 | Yes |
| L-Isoleucine | Psest_1310 | ABC-type branched-chain amino acid transport system, permease component | -1.4 | Yes |
| L-Isoleucine | Psest_1311 | Branched-chain amino acid ABC-type transport system, permease components | -1.4 | Yes |
| L-Isoleucine | Psest_1445 | Curli assembly protein CsgE. | +1.2 | |
| L-Isoleucine | Psest_1576 | Periplasmic glucans biosynthesis protein | variable | |
| L-Isoleucine | Psest_2387 | FolB domain | -1.1 | |
| L-Isoleucine | Psest_2600 | Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis | +1.1 | |
| L-Isoleucine | Psest_2601 | Membrane protein involved in the export of O-antigen and teichoic acid | +1.2 | |
| L-Isoleucine | Psest_2603 | capsular exopolysaccharide family | +1.3 | |
| L-Isoleucine | Psest_2604 | WbqC-like protein family. | +2.2 | |
| L-Isoleucine | Psest_2608 | hypothetical protein | +1.2 | |
| L-Isoleucine | Psest_2609 | Glycosyltransferase | +1.4 | |
| L-Isoleucine | Psest_2890 | diguanylate cyclase (GGDEF) domain | variable | |
| L-Isoleucine | Psest_3085 | methyltransferase, putative | variable | |
| L-Isoleucine | Psest_3086 | hypothetical protein | -1.6 | |
| L-Isoleucine | Psest_3161 | amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family | -1.7 | Yes |
| L-Isoleucine | Psest_3162 | amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family | -1.3 | Yes |
| L-Isoleucine | Psest_3163 | ABC-type amino acid transport/signal transduction systems, periplasmic component/domain | -1.4 | |
| L-Isoleucine | Psest_3192 | diguanylate cyclase (GGDEF) domain | +2.4 | |
| L-Isoleucine | Psest_3321 | Predicted amidohydrolase | -1.3 | |
| L-Isoleucine | Psest_3517 | branched-chain ketoacid ferredoxin reductase (EC 1.2.7.7) active on 4-methyl-2-oxopentanoate, (S)-3-methyl-2-oxopentanoate, or 3-methyl-2-oxobutanoate (from data) | -1.5 | |
| L-Isoleucine | Psest_3841 | D-lactate/glycolate dehydrogenase, FAD-linked subunit GlcD (EC 1.1.99.6; EC 1.1.99.14) (from data) | +1.4 | |
| L-Isoleucine | Psest_0392 | Signal transduction histidine kinase | variable | |
| L-Isoleucine | Psest_4071 | 4-hydroxyphenylpyruvate dioxygenase and related hemolysins | +1.0 | |
| L-Isoleucine | Psest_4072 | Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II | +1.1 | |
| L-Isoleucine | Psest_4297 | PAS domain S-box | variable | |
| L-Isoleucine | Psest_0450 | Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) | -4.4 | Yes |
| L-Isoleucine | Psest_0920 | Transcriptional regulators | -2.1 | Yes |
| L-Proline | Psest_3075 | sodium/proline symporter | -1.2 | |
| L-Proline | Psest_3078 | L-proline:Na+ symporter (from data) | -4.8 | Yes |
| L-Proline | Psest_3079 | L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) | -5.7 | Yes |
| L-Valine | Psest_1083 | 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) | -3.3 | |
| L-Valine | Psest_1084 | Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) | -1.6 | |
| L-Valine | Psest_1187 | exodeoxyribonuclease III | +2.1 | |
| L-Valine | Psest_1402 | Putative threonine efflux protein | -1.3 | |
| L-Valine | Psest_1443 | Uncharacterized protein involved in formation of curli polymers | +1.2 | |
| L-Valine | Psest_1464 | Selenocysteine lyase | -1.3 | |
| L-Valine | Psest_1569 | PAS domain S-box/diguanylate cyclase (GGDEF) domain | +1.3 | |
| L-Valine | Psest_1619 | Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 | -1.4 | |
| L-Valine | Psest_1991 | Glutathione S-transferase | +1.1 | |
| L-Valine | Psest_2158 | alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase | -1.9 | |
| L-Valine | Psest_2435 | Transcriptional regulator | -1.4 | Yes |
| L-Valine | Psest_2436 | Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data) | -1.5 | |
| L-Valine | Psest_2437 | Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data) | -1.9 | Yes |
| L-Valine | Psest_2438 | 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) | -1.8 | |
| L-Valine | Psest_2439 | 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) | -1.3 | Yes |
| L-Valine | Psest_2440 | isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) | -1.5 | Yes |
| L-Valine | Psest_2489 | branched-chain amino acid uptake carrier | +1.4 | Yes |
| L-Valine | Psest_3192 | diguanylate cyclase (GGDEF) domain | +2.3 | |
| L-Valine | Psest_3515 | Na+-dependent transporters of the SNF family | +1.7 | |
| L-Valine | Psest_3517 | branched-chain ketoacid ferredoxin reductase (EC 1.2.7.7) active on 4-methyl-2-oxopentanoate, (S)-3-methyl-2-oxopentanoate, or 3-methyl-2-oxobutanoate (from data) | -2.9 | Yes |
| L-Valine | Psest_3993 | alpha-L-glutamate ligases, RimK family | -1.2 | |
| L-Valine | Psest_4076 | hypothetical protein | +2.1 | |
| L-Valine | Psest_0571 | Transcriptional regulators | -1.2 | |
| L-Valine | Psest_0956 | Transcriptional regulators | +2.2 | |
| Parabanic Acid | Psest_1488 | outer membrane porin, OprD family. | -2.4 | |
| Parabanic Acid | Psest_0545 | urease accessory protein UreG | -4.6 | Yes |
| Parabanic Acid | Psest_0548 | Urease accessory protein UreE | -4.1 | Yes |
| Parabanic Acid | Psest_0557 | Urease (EC 3.5.1.5) (from data) | -3.8 | Yes |
| Parabanic Acid | Psest_0559 | Sortase and related acyltransferases | -1.4 | |
| Parabanic Acid | Psest_0560 | Urease (EC 3.5.1.5) (from data) | -4.4 | Yes |
| Parabanic Acid | Psest_0561 | Urease accessory protein UreH | -4.4 | Yes |
| Parabanic Acid | Psest_0565 | urea ABC transporter, permease protein UrtC | -2.5 | Yes |
| Parabanic Acid | Psest_0566 | urea ABC transporter, permease component (from data) | -3.0 | Yes |
| Parabanic Acid | Psest_0567 | urea ABC transporter, urea binding protein | -2.7 | Yes |
| Putrescine Dihydrochloride | Psest_3793 | D-alanine dehydrogenase (EC 1.4.99.-) (from data) | -1.6 | |
| Putrescine Dihydrochloride | Psest_4281 | ABC-type spermidine/putrescine transport system, permease component I | -4.4 | Yes |
| Putrescine Dihydrochloride | Psest_4282 | spermidine/putrescine ABC transporter ATP-binding subunit | -4.7 | Yes |
| Putrescine Dihydrochloride | Psest_4284 | Spermidine/putrescine-binding periplasmic protein | -3.4 | Yes |
| Putrescine Dihydrochloride | Psest_4285 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | -1.8 | Yes |
| Putrescine Dihydrochloride | Psest_4286 | Glutamine synthetase | -2.1 | Yes |
| Putrescine Dihydrochloride | Psest_4288 | Glutamate--putrescine ligase (EC 6.3.1.11) (from data) | -3.2 | Yes |
| Putrescine Dihydrochloride | Psest_4305 | NAD-dependent aldehyde dehydrogenases | -3.4 | Yes |
| Sodium nitrate | Psest_1925 | uroporphyrin-III C-methyltransferase | -1.7 | Yes |
| Sodium nitrate | Psest_1926 | Uncharacterized anaerobic dehydrogenase | -4.2 | Yes |
| Sodium nitrate | Psest_1928 | Nitrite reductase (NAD(P)H) (EC 1.7.1.4) (from data) | -2.5 | Yes |
| Sodium nitrate | Psest_1936 | Response regulator with putative antiterminator output domain | -2.4 | Yes |
| Sodium nitrate | Psest_2079 | Predicted permeases | -1.5 | |
| Sodium nitrate | Psest_2406 | nitrite reductase [NAD(P)H], large subunit | -1.3 | Yes |
| Sodium nitrate | Psest_2511 | molybdenum cofactor biosynthesis protein A, bacterial | -3.1 | Yes |
| Sodium nitrite | Psest_1123 | adhesin-associated sorting protein (DUF1329) (from data) | +1.5 | |
| Sodium nitrite | Psest_1622 | hypothetical protein | -4.8 | |
| Sodium nitrite | Psest_1925 | uroporphyrin-III C-methyltransferase | -2.9 | |
| Sodium nitrite | Psest_1926 | Uncharacterized anaerobic dehydrogenase | -3.4 | Yes |
| Sodium nitrite | Psest_1928 | Nitrite reductase (NAD(P)H) (EC 1.7.1.4) (from data) | -2.9 | Yes |
| Sodium nitrite | Psest_0190 | Uncharacterized conserved protein | +1.9 | |
| Sodium nitrite | Psest_1935 | hypothetical protein | +1.0 | |
| Sodium nitrite | Psest_1936 | Response regulator with putative antiterminator output domain | -2.5 | Yes |
| Sodium nitrite | Psest_2079 | Predicted permeases | -1.6 | |
| Sodium nitrite | Psest_2261 | hypothetical protein | +1.2 | |
| Sodium nitrite | Psest_0233 | hypothetical protein | variable | |
| Sodium nitrite | Psest_2441 | hypothetical protein | variable | |
| Sodium nitrite | Psest_2551 | 1-aminocyclopropane-1-carboxylate deaminase | +1.4 | |
| Sodium nitrite | Psest_2669 | Acyl-CoA dehydrogenases | variable | |
| Sodium nitrite | Psest_0270 | carbamate kinase | variable | |
| Sodium nitrite | Psest_2949 | Aspartyl aminopeptidase | -1.4 | |
| Sodium nitrite | Psest_3213 | acetate kinase | variable | |
| Sodium nitrite | Psest_3235 | Protein of unknown function (DUF1329). | +1.9 | |
| Sodium nitrite | Psest_3241 | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) | +1.2 | |
| Sodium nitrite | Psest_0351 | hypothetical protein | variable | |
| Sodium nitrite | Psest_3727 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases | +1.3 | |
| Sodium nitrite | Psest_3734 | Uncharacterized protein involved in an early stage of isoprenoid biosynthesis | +1.1 | |
| Sodium nitrite | Psest_3835 | Rubredoxin | -2.6 | |
| Sodium nitrite | Psest_3974 | Anti-sigma regulatory factor (Ser/Thr protein kinase) | +1.4 | |
| Sodium nitrite | Psest_3975 | Signal transduction histidine kinase | +1.1 | |
| Sodium nitrite | Psest_3976 | PAS domain S-box | variable | |
| Sodium nitrite | Psest_3993 | alpha-L-glutamate ligases, RimK family | -1.2 | |
| Sodium nitrite | Psest_4092 | Ectoine synthase. | +1.1 | |
| Sodium nitrite | Psest_0446 | hypothetical protein | +2.1 | |
| Sodium nitrite | Psest_0539 | Acyl-CoA dehydrogenases | variable | |
| Sodium nitrite | Psest_0546 | hypothetical protein | variable | |
| Sodium nitrite | Psest_0006 | alkyl hydroperoxide reductase, F subunit | variable | |
| Sodium nitrite | Psest_0634 | hypothetical protein | -1.5 | |
| Sodium nitrite | Psest_0994 | L-aspartate-alpha-decarboxylase | variable | |
| Urea | Psest_0545 | urease accessory protein UreG | -1.3 | Yes |
| Urea | Psest_0557 | Urease (EC 3.5.1.5) (from data) | -1.1 | Yes |
| Urea | Psest_0560 | Urease (EC 3.5.1.5) (from data) | -1.1 | Yes |