Specific Phenotypes for Sinorhizobium meliloti 1021 in carbon source experiments

Condition Gene Description Fitness Cons.
5-Aminovaleric acid SMc00087 hydrolase -1.7  
5-Aminovaleric acid SMc00768 isocitrate lyase -5.6  
5-Aminovaleric acid SMc00769 hypothetical protein -5.0  
5-Aminovaleric acid SMc00781 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data) +1.3  
5-Aminovaleric acid SMc01946 leucine-specific binding protein -1.2  
5-Aminovaleric acid SMc01949 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -1.9  
5-Aminovaleric acid SMc01950 high-affinity branched-chain amino acid ABC transporter permease -2.0  
5-Aminovaleric acid SMc01951 high-affinity branched-chain amino acid ABC transporter permease -2.0  
5-Aminovaleric acid SMc03879 Acetyl-CoA acetyltransferase (EC 2.3.1.9) (from data) -5.4  
Beta-Lactose SM_b20002 ABC transporter for Lactose, ATPase component (from data) -4.1 Yes
Beta-Lactose SM_b20573 NADH-dependent FMN reductase -1.3  
Beta-Lactose SM_b21650 LacI family transcriptional regulator +2.8  
Beta-Lactose SM_b21652 ABC transporter for Lactose, periplasmic substrate-binding component (from data) -3.6 Yes
Beta-Lactose SM_b21653 ABC transporter for Lactose, permease component 1 (from data) -3.8 Yes
Beta-Lactose SM_b21654 ABC transporter for Lactose, permease component 2 (from data) -3.8  
Beta-Lactose SM_b21655 Beta-galactosidase (EC 3.2.1.23) (from data) -6.3  
Beta-Lactose SM_b21691 nitrilotriacetate monooxygenase subunit A -2.0  
Beta-Lactose SMc00881 2-dehydro-3-deoxygalactonokinase -2.6  
Beta-Lactose SMc03798 aldose 1-epimerase +2.0  
D-(-)-tagatose SM_b21373 D-tagatose 6-phosphate 4-epimerase [EC:5.1.3.40] (from data) -5.2  
D-(-)-tagatose SM_b21375 sugar uptake ABC transporter permease -2.7  
D-(-)-tagatose SM_b21376 sugar uptake ABC transporter ATP-binding protein -3.1  
D-(-)-tagatose SM_b21377 sugar uptake ABC transporter substrate-binding protein precursor -4.0  
D-Arabinose SM_b21101 L-fucono-1,5-lactonase; D-arabinolactonase (from data) -2.3  
D-Arabinose SM_b21112 L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase (from data) -4.3 Yes
D-Arabinose SMa0247 2-dehydro-3-deoxy-D-arabinonate dehydratase, 2,4-dioxopentanoate forming (from data) -5.0 Yes
D-Arabinose SMa2303 ROK family transcriptional regulator +1.8  
D-Arabinose SMc02059 hypothetical protein -1.3 Yes
D-Arabinose SMc02170 ABC transporter permease +1.0  
D-Arabinose SMc02775 D-arabinose 1-dehydrogenase (from data) -2.9  
D-Arabinose SMc02776 D-arabinoate dehydratase (EC 4.2.1.5); also involved in L-fucose catabolism (from data) -4.2 Yes
D-Arabinose SMc02777 transcriptional regulator +2.4  
D-Arabinose SMc02979 hypothetical protein -1.6  
D-Arabinose SMc03164 Xylulose kinase (EC 2.7.1.17) (from data) -2.5 Yes
D-Cellobiose SMc03162 3-ketoglucose dehydratase (from data) -1.6  
D-Cellobiose SMc04253 oxidoreductase -1.6  
D-Cellobiose SMc04256 ABC transporter for D-Cellobiose and D-Salicin, ATPase component (from data) -3.5 Yes
D-Cellobiose SMc04257 ABC transporter for D-Cellobiose and D-Salicin, permease component 1 (from data) -3.4 Yes
D-Cellobiose SMc04258 ABC transporter for D-Cellobiose and D-Salicin, permease component 2 (from data) -3.1 Yes
D-Cellobiose SMc04259 ABC transporter for D-Cellobiose and D-Salicin, periplasmic substrate-binding protein (from data) -3.7 Yes
D-Fructose SMc02045 oxidoreductase -1.0  
D-Fructose SMc02170 ABC transporter permease -2.2 Yes
D-Galactose SMc00881 2-dehydro-3-deoxygalactonokinase -4.8 Yes
D-Glucosamine Hydrochloride SM_b21140 transcriptional regulator +1.2  
D-Glucosamine Hydrochloride SMc00079 hypothetical protein -1.5 Yes
D-Glucosamine Hydrochloride SMc02690 hypothetical protein -3.0  
D-Glucosamine Hydrochloride SMc03923 glucose-1-phosphate adenylyltransferase +1.4  
D-Glucosamine Hydrochloride SMc04460 glycogen phosphorylase +1.3  
D-Leucrose SM_b20325 ABC transporter for D-trehalose/D-maltose/sucrose, substrate-binding component (ThuE) (from data) -3.5 Yes
D-Leucrose SM_b20326 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF) (from data) -3.9 Yes
D-Leucrose SM_b20327 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 2 (ThuG) (from data) -3.3 Yes
D-Leucrose SM_b20328 ABC transporter for D-trehalose/D-maltose/sucrose, ATPase component (ThuK) (from data) -3.6 Yes
D-Leucrose SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) (from data) -5.2 Yes
D-Maltose monohydrate SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) (from data) +2.4  
D-Mannitol SMc01496 sorbitol-binding periplasmic protein -3.2 Yes
D-Mannitol SMc01497 sorbitol/mannitol transport inner membrane transmembrane protein -3.6 Yes
D-Mannitol SMc01498 sorbitol/mannitol transport inner membrane protein -3.9 Yes
D-Mannitol SMc01499 ATP-binding transport ABC transporter protein -3.1 Yes
D-Mannitol SMc01503 sugar kinase -1.8 Yes
D-Mannitol SMc02167 fructose transport system kinase -2.1  
D-Mannitol SMc02171 periplasmic binding ABC transporter protein -4.3  
D-Mannose SMa0062 GntR family transcriptional regulator +1.1  
D-Mannose SMc02979 hypothetical protein -2.6  
D-Mannose SMc03109 Mannokinase (EC 2.7.1.7) (from data) -5.4 Yes
D-Raffinose pentahydrate SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) (from data) -2.0  
D-Raffinose pentahydrate SM_b21643 alpha-galactosidase (melibiase) protein -6.5 Yes
D-Raffinose pentahydrate SM_b21644 ABC transporter for D-Raffinose, ATPase component (from data) -3.4 Yes
D-Raffinose pentahydrate SM_b21645 ABC transporter for D-Raffinose, permease component 1 (from data) -3.7 Yes
D-Raffinose pentahydrate SM_b21646 ABC transporter for D-Raffinose, permease component 2 (from data) -3.5 Yes
D-Raffinose pentahydrate SM_b21647 ABC transporter for D-Raffinose, periplasmic substrate-binding protein (from data) -3.4 Yes
D-Raffinose pentahydrate SM_b21648 Alpha-galactosidase (EC 3.2.1.22) (from data) -3.4 Yes
D-Raffinose pentahydrate SM_b21649 AraC family transcriptional regulator -3.2 Yes
D-Ribose SMc01103 Ribokinase (EC 2.7.1.15) (from data) -3.7 Yes
D-Salicin SM_b21650 LacI family transcriptional regulator +1.5  
D-Salicin SMc03162 3-ketoglucose dehydratase (from data) -2.1  
D-Salicin SMc04253 oxidoreductase -4.2  
D-Salicin SMc04255 beta-mannosidase -3.1  
D-Salicin SMc04256 ABC transporter for D-Cellobiose and D-Salicin, ATPase component (from data) -3.9  
D-Salicin SMc04257 ABC transporter for D-Cellobiose and D-Salicin, permease component 1 (from data) -3.6  
D-Salicin SMc04258 ABC transporter for D-Cellobiose and D-Salicin, permease component 2 (from data) -3.9  
D-Salicin SMc04259 ABC transporter for D-Cellobiose and D-Salicin, periplasmic substrate-binding protein (from data) -4.2  
D-Sorbitol SMc01496 sorbitol-binding periplasmic protein -2.0 Yes
D-Sorbitol SMc01497 sorbitol/mannitol transport inner membrane transmembrane protein -1.9 Yes
D-Sorbitol SMc01498 sorbitol/mannitol transport inner membrane protein -1.9 Yes
D-Sorbitol SMc01499 ATP-binding transport ABC transporter protein -2.1 Yes
D-Sorbitol SMc01503 sugar kinase -1.2 Yes
D-Trehalose dihydrate SM_b20325 ABC transporter for D-trehalose/D-maltose/sucrose, substrate-binding component (ThuE) (from data) -2.9  
D-Trehalose dihydrate SM_b20326 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF) (from data) -2.7 Yes
D-Trehalose dihydrate SM_b20327 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 2 (ThuG) (from data) -3.6  
D-Trehalose dihydrate SM_b20328 ABC transporter for D-trehalose/D-maltose/sucrose, ATPase component (ThuK) (from data) -3.4  
D-Trehalose dihydrate SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) (from data) -5.0  
D-Xylose SMc03163 Xylose isomerase (EC 5.3.1.5) (from data) -3.5 Yes
D-Xylose SMc03164 Xylulose kinase (EC 2.7.1.17) (from data) -3.9 Yes
D-Xylose SMc03165 Novel Xylose regulator from LacI family (from data) -3.5 Yes
Glycerol SM_b21009 Glycerol kinase (EC 2.7.1.30) (from data) -2.5 Yes
Glycerol SMc01023 triosephosphate isomerase -3.2  
Glycerol SMc02079 hypothetical protein +1.1  
L-Alanine SMc01169 alanine dehydrogenase oxidoreductase -1.3 Yes
L-Alanine SMc01949 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -2.1 Yes
L-Alanine SMc01950 high-affinity branched-chain amino acid ABC transporter permease -2.3 Yes
L-Alanine SMc01951 high-affinity branched-chain amino acid ABC transporter permease -2.5 Yes
L-Alanine SMc02118 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, periplasmic substrate-binding component (from data) -1.7 Yes
L-Alanine SMc02119 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 1 (from data) -1.7 Yes
L-Alanine SMc02120 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 2 (from data) -1.3 Yes
L-Arabinose SM_b20890 L-arabonate dehydratase (EC 4.2.1.25) (from data) -5.5 Yes
L-Arabinose SM_b20891 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) (from data) -3.7  
L-Arabinose SM_b20892 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43) (from data) -5.7 Yes
L-Arabinose SM_b20893 sugar uptake ABC transporter permease -2.7 Yes
L-Arabinose SM_b20894 L-arabinose ABC transporter, ATPase component (from data) -3.3 Yes
L-Arabinose SM_b20895 sugar uptake ABC transporter substrate-binding protein precursor -4.2 Yes
L-Arabinose SMa1138 hypothetical protein variable  
L-Arabinose SMc00762 glutamine synthetase -1.6  
L-Arabinose SMc00830 hypothetical protein -1.3 Yes
L-Arabinose SMc00883 L-arabinolactonase/D-galactonolactonase (EC 3.1.1.15; EC 3.1.1.25) (from data) -1.6  
L-Fucose SM_b20483 catabolite repressor protein -1.5  
L-Fucose SM_b20850 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data) -2.1 Yes
L-Fucose SM_b21101 L-fucono-1,5-lactonase; D-arabinolactonase (from data) -1.2 Yes
L-Fucose SM_b21103 ABC transporter for L-Fucose, periplasmic substrate-binding protein (from data) -3.6  
L-Fucose SM_b21104 ABC transporter for L-Fucose, permease component 1 (from data) -3.4  
L-Fucose SM_b21105 ABC transporter for L-Fucose, permease component 2 (from data) -3.3  
L-Fucose SM_b21106 ABC transporter for L-Fucose, ATPase component (from data) -3.0  
L-Fucose SM_b21107 dehydratase involved in L-fucose catabolism (from data) -3.5  
L-Fucose SM_b21108 L-fucose mutarotase (EC 5.1.3.29) (from data) -4.3 Yes
L-Fucose SM_b21109 L-fucose dehydrogenase (EC 1.1.1.122) (from data) -3.9  
L-Fucose SM_b21110 dehydratase involved in L-fucose catabolism (from data) -4.2  
L-Fucose SM_b21111 oxidoreductase, RED superfamily protein -4.9 Yes
L-Fucose SM_b21112 L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase (from data) -6.0 Yes
L-Fucose SMa0078 LacI family transcriptional regulator -1.4  
L-Fucose SMc00820 transcriptional regulator -1.4  
L-Fucose SMc02776 D-arabinoate dehydratase (EC 4.2.1.5); also involved in L-fucose catabolism (from data) -2.8  
L-Glutamine SMc00486 Glutaminase (EC 3.5.1.2) (from data) -5.5 Yes
L-Glutamine SMc01126 malic enzyme -2.0 Yes
L-Glutamine SMc01592 transcriptional regulator -3.3  
L-Glutamine SMc01946 leucine-specific binding protein -1.2  
L-Glutamine SMc01948 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -2.6  
L-Glutamine SMc01949 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -2.4 Yes
L-Glutamine SMc01950 high-affinity branched-chain amino acid ABC transporter permease -2.8  
L-Glutamine SMc01951 high-affinity branched-chain amino acid ABC transporter permease -3.0  
L-Glutamine SMc02118 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, periplasmic substrate-binding component (from data) -2.9  
L-Glutamine SMc02119 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 1 (from data) -2.9  
L-Glutamine SMc02120 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 2 (from data) -2.8  
L-Glutamine SMc02368 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase -1.2 Yes
L-Glutamine SMc02620 hypothetical protein -1.4  
L-Glutamine SMc04093 acetyl-CoA synthetase -2.1  
L-Glutamine SMc04262 6-phosphogluconate dehydrogenase -1.3  
L-Glutamine SMc04263 amino acid carrier transmembrane protein -1.8 Yes
L-Histidine SM_b20048 transcriptional regulator -6.1  
L-Histidine SM_b20501 transcriptional regulator -1.3  
L-Histidine SM_b21163 Urocanate hydratase (EC 4.2.1.49) (from data) -5.4 Yes
L-Histidine SM_b21164 N-formylglutamate deformylase (EC 3.5.1.68) (from data) -4.4 Yes
L-Histidine SM_b21165 Histidine ammonia-lyase (EC 4.3.1.3) (from data) -4.9 Yes
L-Histidine SM_b21166 Imidazolonepropionase (EC 3.5.2.7) (from data) -6.3 Yes
L-Histidine SMa0078 LacI family transcriptional regulator -1.4  
L-Histidine SMa1654 GntR family transcriptional regulator -1.6  
L-Histidine SMc00670 histidine transport ATP-binding ABC transporter protein -1.1 Yes
L-Histidine SMc00672 histidine-binding periplasmic signal peptide protein -1.1 Yes
L-Histidine SMc00673 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) -6.5 Yes
L-Histidine SMc01126 malic enzyme -1.4  
L-Histidine SMc01418 signal peptide protein +1.4  
L-Histidine SMc01592 transcriptional regulator -2.4  
L-Histidine SMc01946 leucine-specific binding protein -1.7  
L-Histidine SMc01948 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -2.6  
L-Histidine SMc01949 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -2.0  
L-Histidine SMc01950 high-affinity branched-chain amino acid ABC transporter permease -2.2  
L-Histidine SMc01951 high-affinity branched-chain amino acid ABC transporter permease -2.6  
L-Histidine SMc02118 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, periplasmic substrate-binding component (from data) -2.6 Yes
L-Histidine SMc02119 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 1 (from data) -2.4 Yes
L-Histidine SMc02120 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 2 (from data) -2.5 Yes
L-Histidine SMc02689 aldehyde dehydrogenase -1.3  
L-Histidine SMc04093 acetyl-CoA synthetase -2.2  
L-Leucine SM_b20757 methylmalonyl-CoA mutase -4.7  
L-Leucine SM_b21120 hypothetical protein -3.1  
L-Leucine SM_b21121 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) -3.8 Yes
L-Leucine SM_b21122 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) -4.7 Yes
L-Leucine SM_b21124 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) -5.1 Yes
L-Leucine SM_b21125 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) (from data) -6.8  
L-Leucine SMc00087 hydrolase -1.6  
L-Leucine SMc00768 isocitrate lyase -7.0 Yes
L-Leucine SMc00769 hypothetical protein -5.5  
L-Leucine SMc00774 Acetoacetate--CoA ligase (EC 6.2.1.16) (from data) -3.0  
L-Leucine SMc02181 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase -1.6 Yes
L-Leucine SMc03201 branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data) -4.0 Yes
L-Leucine SMc03202 branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) (from data) -3.6 Yes
L-Leucine SMc03203 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) -3.8 Yes
L-Leucine SMc03204 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data) -2.9 Yes
L-Lysine SM_b20196 CbbX protein -2.4  
L-Lysine SM_b20197 ribulose-1,5-bisphosphate carboxylase small subunit (EC 4.1.1.39) (from data) -3.7  
L-Lysine SM_b20198 ribulose bisophosphate carboxylase -3.3  
L-Lysine SM_b20200 transketolase -1.0  
L-Lysine SM_b21133 sulfate ABC transporter substrate-binding protein -1.5  
L-Lysine SMa0496 hypothetical protein +1.5  
L-Lysine SMc00138 L-lysine ABC transporter, permease component 2 (from data) -2.6 Yes
L-Lysine SMc00139 L-lysine ABC transporter, permease component 1 (from data) -2.9 Yes
L-Lysine SMc00140 L-lysine ABC transporter, substrate-binding component (from data) -2.4  
L-Lysine SMc00151 phosphoglycolate phosphatase -1.6  
L-Lysine SMc00167 signal peptide protein variable  
L-Lysine SMc00768 isocitrate lyase -6.0  
L-Lysine SMc00769 hypothetical protein -5.4  
L-Lysine SMc01946 leucine-specific binding protein -1.4  
L-Lysine SMc01950 high-affinity branched-chain amino acid ABC transporter permease -1.7  
L-Lysine SMc01951 high-affinity branched-chain amino acid ABC transporter permease -1.5  
L-Lysine SMc03131 amino acid-binding periplasmic ABC transporter protein -2.0  
L-Lysine SMc03132 oxidoreductase -1.6  
L-Lysine SMc03133 amino-acid transport system permease ABC transporter protein -2.0  
L-Lysine SMc03879 Acetyl-CoA acetyltransferase (EC 2.3.1.9) (from data) -5.1 Yes
L-Lysine SMc04386 2-aminoadipate:2-oxoglutarate aminotransferase (EC 2.6.1.39) (from data) -3.9  
L-Malic acid disodium salt monohydrate SM_b20611 C4-dicarboxylate transporter DctA -3.8 Yes
L-Malic acid disodium salt monohydrate SM_b20612 C4-dicarboxylate transport sensor protein -4.2 Yes
L-Pipecolic Acid SM_b20196 CbbX protein -3.9  
L-Pipecolic Acid SM_b20197 ribulose-1,5-bisphosphate carboxylase small subunit (EC 4.1.1.39) (from data) -5.3  
L-Pipecolic Acid SM_b20198 ribulose bisophosphate carboxylase -4.4  
L-Pipecolic Acid SM_b20199 fructose-1,6-bisphosphate aldolase -2.8  
L-Pipecolic Acid SM_b20200 transketolase -3.4  
L-Pipecolic Acid SM_b20624 methylthioribose-1-phosphate isomerase -1.3  
L-Pipecolic Acid SMa0113 Sensor histidine kinase +1.5  
L-Pipecolic Acid SMc00034 oxidoreductase -1.5  
L-Pipecolic Acid SMc00151 phosphoglycolate phosphatase -1.9  
L-Pipecolic Acid SMc00768 isocitrate lyase -5.4  
L-Pipecolic Acid SMc00769 hypothetical protein -5.0  
L-Pipecolic Acid SMc00833 D-lactate dehydrogenase, FAD binding subunit GlcE (EC 1.1.99.6) (from data) -1.0  
L-Pipecolic Acid SMc00926 D-lactate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6) (from data) -1.1  
L-Pipecolic Acid SMc01108 tRNA (guanine-N(7)-)-methyltransferase -1.6  
L-Pipecolic Acid SMc01576 oxidoreductase -6.5  
L-Pipecolic Acid SMc01947 hypothetical protein -2.0  
L-Pipecolic Acid SMc01948 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -3.7  
L-Pipecolic Acid SMc01949 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -3.0  
L-Pipecolic Acid SMc01950 high-affinity branched-chain amino acid ABC transporter permease -2.9  
L-Pipecolic Acid SMc01951 high-affinity branched-chain amino acid ABC transporter permease -3.1  
L-Pipecolic Acid SMc02117 cystathionine beta-lyase -1.2  
L-Pipecolic Acid SMc02253 salicylate biosynthesis protein -2.3  
L-Pipecolic Acid SMc02378 periplasmic binding transmembrane protein -1.3  
L-Pipecolic Acid SMc02379 permease -2.1  
L-Pipecolic Acid SMc03879 Acetyl-CoA acetyltransferase (EC 2.3.1.9) (from data) -3.1  
L-Pipecolic Acid SMc04386 2-aminoadipate:2-oxoglutarate aminotransferase (EC 2.6.1.39) (from data) -3.3  
L-Pipecolic Acid SMc04439 glycine betaine transport ATP-binding ABC transporter protein -1.7  
L-Proline SM_b20196 CbbX protein -4.9  
L-Proline SM_b20197 ribulose-1,5-bisphosphate carboxylase small subunit (EC 4.1.1.39) (from data) -5.5  
L-Proline SM_b20198 ribulose bisophosphate carboxylase -6.6  
L-Proline SM_b20199 fructose-1,6-bisphosphate aldolase -3.7  
L-Proline SM_b20200 transketolase -5.1  
L-Proline SMc00151 phosphoglycolate phosphatase -2.2  
L-Proline SMc00681 leucine-responsive regulatory protein -6.3 Yes
L-Proline SMc01126 malic enzyme -2.2  
L-Proline SMc01174 cysteine synthase A -1.4  
L-Proline SMc01592 transcriptional regulator -4.2  
L-Proline SMc01948 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -2.5 Yes
L-Proline SMc01949 high-affinity branched-chain amino acid ABC transporter ATP-binding protein -2.6 Yes
L-Proline SMc01950 high-affinity branched-chain amino acid ABC transporter permease -3.0 Yes
L-Proline SMc01951 high-affinity branched-chain amino acid ABC transporter permease -2.5 Yes
L-Proline SMc02181 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase -5.7 Yes
L-Proline SMc02379 permease -1.2  
L-Proline SMc04093 acetyl-CoA synthetase -1.5  
L-Proline SMc04262 6-phosphogluconate dehydrogenase -1.3  
L-Rhamnose monohydrate SM_b20850 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data) -1.7  
L-Rhamnose monohydrate SMc02321 L-rhamnose isomerase (EC 5.3.1.14) (from data) -3.7 Yes
L-Rhamnose monohydrate SMc02322 rhamnulose-1-phosphate aldolase (EC 4.1.2.19) / lactaldehyde dehydrogenase (EC 1.2.1.22) (from data) -4.6 Yes
L-Rhamnose monohydrate SMc02323 transcriptional regulator -2.7 Yes
L-Rhamnose monohydrate SMc02324 periplasmic binding ABC transporter protein -3.1 Yes
L-Rhamnose monohydrate SMc02325 ABC transporter ATP-binding protein -2.8 Yes
L-Rhamnose monohydrate SMc03000 ABC transporter permease -3.3 Yes
L-Rhamnose monohydrate SMc03001 ABC transporter permease -3.9 Yes
L-Rhamnose monohydrate SMc03002 hypothetical protein -3.1 Yes
L-Rhamnose monohydrate SMc03003 Rhamnulokinase RhaK in alpha-proteobacteria (EC 2.7.1.5) (from data) -4.3 Yes
Lactitol SM_b20757 methylmalonyl-CoA mutase -1.5  
Lactitol SM_b21644 ABC transporter for D-Raffinose, ATPase component (from data) -1.3  
Lactitol SM_b21646 ABC transporter for D-Raffinose, permease component 2 (from data) -1.5  
Lactitol SM_b21647 ABC transporter for D-Raffinose, periplasmic substrate-binding protein (from data) -1.4  
Lactitol SM_b21650 LacI family transcriptional regulator +9.3  
Lactitol SM_b21652 ABC transporter for Lactose, periplasmic substrate-binding component (from data) -1.8 Yes
Lactitol SM_b21654 ABC transporter for Lactose, permease component 2 (from data) -1.3  
Lactitol SM_b21655 Beta-galactosidase (EC 3.2.1.23) (from data) -2.8  
Lactitol SMa2303 ROK family transcriptional regulator +8.6  
Lactitol SMa2305 ABC transporter substrate-binding protein +1.7  
Lactitol SMa2307 ABC transporter permease +4.6  
Lactitol SMc01499 ATP-binding transport ABC transporter protein -1.2  
Lactitol SMc01592 transcriptional regulator -1.8  
Lactitol SMc03798 aldose 1-epimerase +1.6  
Lactitol SMc04253 oxidoreductase +3.3 Yes
Lactitol SMc04254 hypothetical protein +2.9 Yes
Lactitol SMc04255 beta-mannosidase +2.0  
Lactitol SMc04256 ABC transporter for D-Cellobiose and D-Salicin, ATPase component (from data) -2.0 Yes
Lactitol SMc04257 ABC transporter for D-Cellobiose and D-Salicin, permease component 1 (from data) -1.7 Yes
Lactitol SMc04258 ABC transporter for D-Cellobiose and D-Salicin, permease component 2 (from data) -1.4 Yes
Lactulose SM_b20002 ABC transporter for Lactose, ATPase component (from data) -5.1 Yes
Lactulose SM_b21650 LacI family transcriptional regulator +2.0  
Lactulose SM_b21652 ABC transporter for Lactose, periplasmic substrate-binding component (from data) -4.5 Yes
Lactulose SM_b21653 ABC transporter for Lactose, permease component 1 (from data) -4.2 Yes
Lactulose SM_b21654 ABC transporter for Lactose, permease component 2 (from data) -3.8  
Lactulose SM_b21655 Beta-galactosidase (EC 3.2.1.23) (from data) -5.7  
Lactulose SMc00881 2-dehydro-3-deoxygalactonokinase -2.7  
Lactulose SMc03798 aldose 1-epimerase +1.7  
Maltitol SM_b20325 ABC transporter for D-trehalose/D-maltose/sucrose, substrate-binding component (ThuE) (from data) -3.8 Yes
Maltitol SM_b20326 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF) (from data) -4.5 Yes
Maltitol SM_b20327 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 2 (ThuG) (from data) -3.7 Yes
Maltitol SM_b20328 ABC transporter for D-trehalose/D-maltose/sucrose, ATPase component (ThuK) (from data) -2.6 Yes
Maltitol SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) (from data) -4.2 Yes
Maltitol SMc01496 sorbitol-binding periplasmic protein -1.6  
Maltitol SMc01497 sorbitol/mannitol transport inner membrane transmembrane protein -2.0  
Maltitol SMc01498 sorbitol/mannitol transport inner membrane protein -1.6 Yes
Maltitol SMc01499 ATP-binding transport ABC transporter protein -1.7  
Maltitol SMc01500 sorbitol dehydrogenase -2.6  
Maltitol SMc02677 pyrroline-5-carboxylate reductase -1.9  
Maltitol SMc03987 transport transmembrane protein -1.6  
Mannobiose SMc03109 Mannokinase (EC 2.7.1.7) (from data) -5.7  
Mannobiose SMc03110 hypothetical protein -2.1  
Mannobiose SMc04255 beta-mannosidase -4.7 Yes
Mannobiose SMc04256 ABC transporter for D-Cellobiose and D-Salicin, ATPase component (from data) -3.7 Yes
Mannobiose SMc04257 ABC transporter for D-Cellobiose and D-Salicin, permease component 1 (from data) -3.8 Yes
Mannobiose SMc04258 ABC transporter for D-Cellobiose and D-Salicin, permease component 2 (from data) -3.3 Yes
Mannobiose SMc04259 ABC transporter for D-Cellobiose and D-Salicin, periplasmic substrate-binding protein (from data) -4.6 Yes
Methyl beta-D-glucopyranoside SMa0717 hypothetical protein -1.1  
Methyl beta-D-glucopyranoside SMc03162 3-ketoglucose dehydratase (from data) -4.2  
Methyl beta-D-glucopyranoside SMc04253 oxidoreductase -4.9  
Methyl beta-D-glucopyranoside SMc04255 beta-mannosidase -3.9  
Methyl beta-D-glucopyranoside SMc04256 ABC transporter for D-Cellobiose and D-Salicin, ATPase component (from data) -4.7  
Methyl beta-D-glucopyranoside SMc04257 ABC transporter for D-Cellobiose and D-Salicin, permease component 1 (from data) -4.3  
Methyl beta-D-glucopyranoside SMc04258 ABC transporter for D-Cellobiose and D-Salicin, permease component 2 (from data) -5.2  
Methyl beta-D-glucopyranoside SMc04259 ABC transporter for D-Cellobiose and D-Salicin, periplasmic substrate-binding protein (from data) -4.5  
Myristic acid SM_b20345 efflux protein -4.2  
Myristic acid SM_b20346 efflux protein -4.1  
Myristic acid SM_b20347 transcriptional regulator -2.5  
Myristic acid SM_b20757 methylmalonyl-CoA mutase -4.3  
Myristic acid SM_b20834 surface saccharide synthesis protein -2.3  
Myristic acid SM_b21261 mureinpeptideoligopeptide ABC transporter substrate-binding protein precursor -1.2  
Myristic acid SMa0113 Sensor histidine kinase +1.9  
Myristic acid SMa0114 two-component response regulator +1.4  
Myristic acid SMc00087 hydrolase -3.1  
Myristic acid SMc00147 hypothetical protein +1.8  
Myristic acid SMc00322 hypothetical protein -1.3  
Myristic acid SMc00768 isocitrate lyase -5.5  
Myristic acid SMc00769 hypothetical protein -5.1  
Myristic acid SMc00977 acyl-CoA dehydrogenase -6.1  
Myristic acid SMc01114 phoH-like protein -1.8  
Myristic acid SMc01418 signal peptide protein +1.5  
Myristic acid SMc02079 hypothetical protein +3.3 Yes
Myristic acid SMc02162 long-chain-fatty-acid--CoA ligase -5.4 Yes
Myristic acid SMc02270 capsular polysaccharide biosynthesis\export transmembrane protein -2.6  
Myristic acid SMc02271 ribitol type dehydrogenase -2.6  
Myristic acid SMc02403 murein transglycosylase -1.2  
Myristic acid SMc02702 hypothetical protein -1.2  
Myristic acid SMc03167 multidrug efflux system protein -2.6  
Myristic acid SMc03168 multidrug efflux system protein -2.6  
Myristic acid SMc03879 Acetyl-CoA acetyltransferase (EC 2.3.1.9) (from data) -1.8  
Myristic acid SMc03969 hypothetical protein +1.5  
N-Acetyl-D-Glucosamine SM_b20901 transcriptional regulator +1.4 Yes
N-Acetyl-D-Glucosamine SMc00490 transcriptional regulator -1.5  
N-Acetyl-D-Glucosamine SMc02677 pyrroline-5-carboxylate reductase -1.7  
N-Acetyl-D-Glucosamine SMc02869 N-Acetyl-D-glucosamine ABC transport system, ATPase component (from data) -3.5 Yes
N-Acetyl-D-Glucosamine SMc02870 oxidoreductase -2.9 Yes
N-Acetyl-D-Glucosamine SMc02871 ABC transporter for N-Acetyl-D-glucosamine, permease protein 2 (from data) -3.9 Yes
N-Acetyl-D-Glucosamine SMc02872 ABC transporter for N-Acetyl-D-glucosamine, permease protein 1 (from data) -3.5 Yes
N-Acetyl-D-Glucosamine SMc02873 N-Acetyl-D-glucosamine ABC transport system, periplasmic substrate-binding component (from data) -3.9 Yes
N-Acetyl-D-Glucosamine SMc02874 N-acetylmuramic acid 6-phosphate etherase -4.5 Yes
N-Acetyl-D-Glucosamine SMc02875 N-acetylglucosamine kinase (EC 2.7.1.59) (from data) -5.2 Yes
N-Acetyl-D-Glucosamine SMc03887 amino acid efflux protein -2.0  
Potassium acetate SM_b20313 glycerone kinase -2.7  
Potassium acetate SMc00103 alpha-halocarboxylic acid dehalogenase -3.6  
Potassium acetate SMc00468 hypothetical protein +1.1  
Potassium acetate SMc00483 glutamate racemase -2.4  
Potassium acetate SMc00768 isocitrate lyase -5.1 Yes
Potassium acetate SMc00769 hypothetical protein -5.0  
Potassium acetate SMc02249 sensory transduction histidine kinase transmembrane protein -4.7 Yes
Potassium acetate SMc04043 hypothetical protein -2.1  
Potassium acetate SMc04093 acetyl-CoA synthetase -5.1 Yes
Protocatechuic Acid SM_b20576 protocatechuate 3,4-dioxygenase subunit alpha -2.3 Yes
Protocatechuic Acid SM_b20577 protocatechuate 3,4-dioxygenase subunit beta -2.7 Yes
Protocatechuic Acid SM_b20579 beta-ketoadipate enol-lactone hydrolase -3.9 Yes
Protocatechuic Acid SM_b20587 CoA-transferase subunit A protein -5.6  
Protocatechuic Acid SM_b20588 CoA-transferase subunit B protein -6.6  
Protocatechuic Acid SM_b20589 beta-ketoadipyl CoA thiolase -5.9 Yes
Protocatechuic Acid SM_b21000 transporter -1.5  
Protocatechuic Acid SMc00087 hydrolase -1.2  
Protocatechuic Acid SMc00481 hypothetical protein -4.2  
Protocatechuic Acid SMc00705 signal peptide protein -1.7  
Protocatechuic Acid SMc00948 glutamine synthetase -1.5  
Protocatechuic Acid SMc01764 arginyl-tRNA-protein transferase +1.9  
Protocatechuic Acid SMc02403 murein transglycosylase -1.5  
Protocatechuic Acid SMc02903 hypothetical protein +1.5  
Protocatechuic Acid SMc04043 hypothetical protein +1.5  
Sodium D,L-Lactate SM_b20850 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data) -1.2 Yes
Sodium D,L-Lactate SMc00832 D-lactate dehydrogenase, FAD-linked subunit GlcD (EC 1.1.99.6) (from data) -2.8 Yes
Sodium D,L-Lactate SMc00833 D-lactate dehydrogenase, FAD binding subunit GlcE (EC 1.1.99.6) (from data) -2.4 Yes
Sodium D,L-Lactate SMc00926 D-lactate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6) (from data) -2.7 Yes
Sodium D,L-Lactate SMc01592 transcriptional regulator -2.2  
Sodium D,L-Lactate SMc04248 hypothetical protein +1.2  
Sodium D,L-Lactate SMc04249 hypothetical protein +1.2  
Sodium D,L-Lactate SMc04251 dctP-like component of a pyruvate transporter (from data) +1.1  
Sodium Fumarate dibasic SM_b20611 C4-dicarboxylate transporter DctA -5.0 Yes
Sodium Fumarate dibasic SM_b20612 C4-dicarboxylate transport sensor protein -4.9 Yes
Sodium L-Lactate SM_b20850 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data) -4.8 Yes
Sodium L-Lactate SMc00356 lysyl-tRNA synthetase -1.7  
Sodium L-Lactate SMc01712 L-lactate dehydrogenase (cytochrome) protein -1.4  
Sodium pyruvate SMc00356 lysyl-tRNA synthetase -1.4  
Sodium pyruvate SMc02249 sensory transduction histidine kinase transmembrane protein -2.4 Yes
Sodium succinate dibasic hexahydrate SM_b20611 C4-dicarboxylate transporter DctA -4.8 Yes
Sodium succinate dibasic hexahydrate SM_b20612 C4-dicarboxylate transport sensor protein -4.6 Yes
Sucrose SMc03064 alpha-glucosidase -1.3 Yes
Uridine SM_b20483 catabolite repressor protein +1.4  
Uridine SM_b21346 LacI family transcriptional regulator +1.2  
Uridine SMc00781 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data) -2.4 Yes
Uridine SMc01103 Ribokinase (EC 2.7.1.15) (from data) -5.3 Yes
Uridine SMc01105 uridine nucleosidase (EC 3.2.2.3) (from data) -1.8 Yes
Uridine SMc02170 ABC transporter permease -1.6  
Uridine SMc02171 periplasmic binding ABC transporter protein -2.1  
Uridine SMc02777 transcriptional regulator +1.7  
Uridine SMc02884 lipoprotein -1.1  
Uridine SMc04126 ABC transporter permease -1.2  
Uridine SMc04127 ABC transporter ATP-binding protein -1.3  
Xylobiose SM_b20483 catabolite repressor protein -1.6  
Xylobiose SMc02468 hypothetical protein -5.1 Yes
Xylobiose SMc02469 oxidoreductase -4.4 Yes
Xylobiose SMc02471 periplasmic binding ABC transporter protein -5.2 Yes
Xylobiose SMc02472 ABC transporter permease -4.7 Yes
Xylobiose SMc02473 ABC transporter permease -4.4 Yes
Xylobiose SMc03163 Xylose isomerase (EC 5.3.1.5) (from data) -4.2 Yes
Xylobiose SMc03164 Xylulose kinase (EC 2.7.1.17) (from data) -4.6 Yes
m-Inositol SM_b20712 rhizopine uptake ABC transporter substrate-binding protein precursor -2.8 Yes
m-Inositol SM_b20713 sugar uptake ABC transporter ATP-binding protein -3.3 Yes
m-Inositol SM_b20714 sugar uptake ABC transporter permease -2.7 Yes
m-Inositol SM_b20899 Inositol 2-dehydrogenase (EC 1.1.1.18) (from data) -4.0 Yes
m-Inositol SMc00432 5-deoxy-D-glucuronate isomerase (EC 5.3.1.30) (from data) -4.3 Yes
m-Inositol SMc00433 Myo-inosose-2 dehydratase (EC 4.2.1.44) (from data) -3.7 Yes
m-Inositol SMc00780 transcriptional regulator -3.5 Yes
m-Inositol SMc00781 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data) -4.6 Yes
m-Inositol SMc01165 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) (from data) -3.6 Yes
m-Inositol SMc01166 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) (from data) -3.3 Yes
methyl 3-keto-a-D-glucopyranoside SM_b20325 ABC transporter for D-trehalose/D-maltose/sucrose, substrate-binding component (ThuE) (from data) -3.1 Yes
methyl 3-keto-a-D-glucopyranoside SM_b20326 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF) (from data) -4.5 Yes
methyl 3-keto-a-D-glucopyranoside SM_b20717 LacI family transcriptional regulator -1.6  
methyl 3-keto-a-D-glucopyranoside SMc03162 3-ketoglucose dehydratase (from data) -2.3  
methyl 3-keto-a-D-glucopyranoside SMc04262 6-phosphogluconate dehydrogenase -1.5  
methyl-beta-D-xylopyranoside SMc02468 hypothetical protein -4.5 Yes
methyl-beta-D-xylopyranoside SMc02469 oxidoreductase -5.1 Yes
methyl-beta-D-xylopyranoside SMc02470 transcriptional regulator -4.9 Yes
methyl-beta-D-xylopyranoside SMc03162 3-ketoglucose dehydratase (from data) -2.7 Yes
methyl-beta-D-xylopyranoside SMc03163 Xylose isomerase (EC 5.3.1.5) (from data) -4.7 Yes
methyl-beta-D-xylopyranoside SMc03164 Xylulose kinase (EC 2.7.1.17) (from data) -4.9 Yes
methyl-beta-D-xylopyranoside SMc03997 hypothetical protein -2.6 Yes
methyl-beta-D-xylopyranoside SMc04262 6-phosphogluconate dehydrogenase -3.2  
palatinose hydrate SM_b20325 ABC transporter for D-trehalose/D-maltose/sucrose, substrate-binding component (ThuE) (from data) -5.0 Yes
palatinose hydrate SM_b20326 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF) (from data) -4.8 Yes
palatinose hydrate SM_b20327 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 2 (ThuG) (from data) -4.8 Yes
palatinose hydrate SM_b20328 ABC transporter for D-trehalose/D-maltose/sucrose, ATPase component (ThuK) (from data) -3.8 Yes
palatinose hydrate SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) (from data) -4.6 Yes