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Specific Phenotypes for
Escherichia coli Nissle 1917
in carbon source experiments
Condition
Gene
Description
Fitness
Cons.
Casamino-acids
ECOLIN
_RS14195
phosphoribosylglycinamide formyltransferase
-4.5
Yes
Casamino-acids
ECOLIN
_RS23035
thiamine phosphate synthase
-1.2
Yes
Casamino-acids
ECOLIN
_RS23040
phosphomethylpyrimidine synthase ThiC
-1.6
Yes
Casamino-acids
ECOLIN
_RS24045
aspartate ammonia-lyase
-2.2
Yes
D-Glucose
ECOLIN
_RS00405
leu operon leader peptide
+1.9
D-Glucose
ECOLIN
_RS11310
H-NS family nucleoid-associated regulatory protein
+2.4
D-Glucose
ECOLIN
_RS15385
sulfate adenylyltransferase subunit CysD
+1.7
Yes
D-Glucose
ECOLIN
_RS16700
N(6)-hydroxylysine O-acetyltransferase IucB
+1.0
D-Glucose
ECOLIN
_RS18535
cell division protein ZapE
+2.6
D-Glucose
ECOLIN
_RS21650
acetolactate synthase 2 catalytic subunit
+1.6
D-Glucose
ECOLIN
_RS21695
guanosine-5'-triphosphate,3'-diphosphate diphosphatase
+3.1
D-Glucose
ECOLIN
_RS31555
pheA operon leader peptide PheL
+1.9
L-Arabinose
ECOLIN
_RS00045
transaldolase
+2.6
L-Arabinose
ECOLIN
_RS00325
L-ribulose-5-phosphate 4-epimerase
-2.4
Yes
L-Arabinose
ECOLIN
_RS00340
arabinose operon transcriptional regulator AraC
+2.9
Yes
L-Arabinose
ECOLIN
_RS00405
leu operon leader peptide
+3.5
L-Arabinose
ECOLIN
_RS00835
bifunctional glycosyl transferase/transpeptidase
-3.6
Yes
L-Arabinose
ECOLIN
_RS08950
Re/Si-specific NAD(P)(+) transhydrogenase subunit beta
+3.2
L-Arabinose
ECOLIN
_RS11310
H-NS family nucleoid-associated regulatory protein
+2.9
L-Arabinose
ECOLIN
_RS13965
oxygen-dependent coproporphyrinogen oxidase
+1.5
L-Arabinose
ECOLIN
_RS15525
two-component sensor histidine kinase BarA
+1.9
L-Arabinose
ECOLIN
_RS15945
arabinose-proton symporter AraE
+2.6
Yes
L-Arabinose
ECOLIN
_RS16690
NADPH-dependent L-lysine N(6)-monooxygenase IucD
+2.2
L-Arabinose
ECOLIN
_RS16695
NIS family aerobactin synthetase IucC
+1.4
L-Arabinose
ECOLIN
_RS16700
N(6)-hydroxylysine O-acetyltransferase IucB
+2.2
L-Arabinose
ECOLIN
_RS16705
aerobactin synthase IucA
+2.4
L-Arabinose
ECOLIN
_RS18535
cell division protein ZapE
+5.1
L-Arabinose
ECOLIN
_RS19240
bifunctional acetylornithine/succinyldiaminopimelate transaminase
+1.5
L-Arabinose
ECOLIN
_RS21650
acetolactate synthase 2 catalytic subunit
+2.1
L-Arabinose
ECOLIN
_RS21695
guanosine-5'-triphosphate,3'-diphosphate diphosphatase
+3.8
L-Arabinose
ECOLIN
_RS22835
phosphoenolpyruvate carboxylase
+1.4
Yes
L-Arabinose
ECOLIN
_RS23015
2-iminoacetate synthase ThiH
-1.2
L-Arabinose
ECOLIN
_RS23035
thiamine phosphate synthase
-1.2
Yes
L-Arabinose
ECOLIN
_RS25210
murein transglycosylase
-4.0
Yes
L-Rhamnose
ECOLIN
_RS00840
ferrichrome porin FhuA
+1.1
L-Rhamnose
ECOLIN
_RS17620
bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase
-1.1
Yes
L-Rhamnose
ECOLIN
_RS20000
damage-inducible type I toxin DinQ
+1.5
L-Rhamnose
ECOLIN
_RS21350
tryptophanase leader peptide
+1.1
L-Rhamnose
ECOLIN
_RS21355
tryptophanase
+1.2
L-Rhamnose
ECOLIN
_RS21360
low affinity tryptophan permease TnaB
+1.3
L-Rhamnose
ECOLIN
_RS22480
rhamnulose-1-phosphate aldolase
-1.4
Yes
L-Rhamnose
ECOLIN
_RS22485
L-rhamnose isomerase
+5.5
Yes
L-Rhamnose
ECOLIN
_RS22490
rhamnulokinase
+5.4
Yes
L-Rhamnose
ECOLIN
_RS22500
HTH-type transcriptional activator RhaS
+8.3
Yes
L-Rhamnose
ECOLIN
_RS22505
HTH-type transcriptional activator RhaR
+8.6
Yes
L-Rhamnose
ECOLIN
_RS22510
L-rhamnose/proton symporter RhaT
+4.9
Yes
L-Rhamnose
ECOLIN
_RS22835
phosphoenolpyruvate carboxylase
-1.5
Sodium-DL-Lactate
ECOLIN
_RS00010
bifunctional aspartate kinase/homoserine dehydrogenase I
-2.7
Sodium-DL-Lactate
ECOLIN
_RS14700
bifunctional chorismate mutase/prephenate dehydrogenase
-3.8
Sodium-DL-Lactate
ECOLIN
_RS14705
3-deoxy-7-phosphoheptulonate synthase AroF
-1.5
Yes
Sodium-DL-Lactate
ECOLIN
_RS15385
sulfate adenylyltransferase subunit CysD
-1.8
Yes
Sodium-DL-Lactate
ECOLIN
_RS19285
siroheme synthase CysG
-1.9
Sodium-DL-Lactate
ECOLIN
_RS20570
L-lactate permease
-1.5
Yes
Sodium-DL-Lactate
ECOLIN
_RS21670
threonine ammonia-lyase, biosynthetic
-3.0
Sodium-DL-Lactate
ECOLIN
_RS22835
phosphoenolpyruvate carboxylase
-3.1
Yes