Fitness data for Rv3823c in Mycobacterium tuberculosis H37Rv

Conserved integral membrane transport protein MmpL8
KEGG: putative drug exporter of the RND superfamily

All 101 fitness values, sorted by group and condition


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group condition fitness t score  
carbon source casaminos 1 mg/mL (C) -0.6 -4.6 compare
casaminos 1 mg/mL (C) -0.2 -1.6 compare
D,L-Malic Acid 10 mM (C) -0.1 -0.6 compare
D,L-Malic Acid 10 mM (C) -0.4 -2.9 compare
D-Glucose (C) -0.4 -3.1 compare
D-Glucose (C) -0.4 -2.9 compare
D-Trehalose 10 mM (C) -0.5 -3.3 compare
D-Trehalose 10 mM (C) -0.4 -3.2 compare
Glycerol (C) -0.6 -4.1 compare
Glycerol (C) -0.8 -6.3 compare
heptadecanoic 250 uM (C) -0.8 -5.0 compare
heptadecanoic 250 uM (C) -0.8 -5.2 compare
L-Asparagine (C) -0.7 -4.8 compare
L-Asparagine (C) -1.1 -8.3 compare
L-Aspartic Acid (C) -0.6 -4.2 compare
L-Aspartic Acid (C) -0.7 -6.0 compare
L-Glutamine (C) -0.5 -4.4 compare
L-Glutamine (C) -0.6 -4.3 compare
Palmitic 100 uM (C) -0.3 -1.8 compare
Palmitic 100 uM (C) -0.2 -1.5 compare
acetate (C) -0.2 -1.5 compare
acetate (C) -0.3 -2.5 compare
butyrate 10 mM (C) -0.6 -4.6 compare
butyrate 10 mM (C) -0.6 -4.2 compare
D-Lactate 10 mM (C) +0.1 +0.4 compare
D-Lactate 10 mM (C) -0.2 -1.1 compare
L-Lactate 10 mM (C) -0.5 -4.1 compare
L-Lactate 10 mM (C) -0.4 -2.8 compare
propionate (C) -1.2 -7.6 compare
propionate (C) -1.3 -8.5 compare
pyruvate (C) -0.2 -1.3 compare
pyruvate (C) -0.0 -0.1 compare
Stearic 100 uM (C) -0.9 -5.7 compare
Stearic 100 uM (C) -0.9 -6.2 compare
Valeric 10 mM (C) -0.7 -5.5 compare
Valeric 10 mM (C) -1.2 -9.0 compare
nitrogen source Glycine 10 mM (N) -0.2 -1.6 compare
Glycine 10 mM (N) -0.4 -2.7 compare
L-Alanine 10 mM (N) -0.1 -0.5 compare
L-Alanine 10 mM (N) -0.4 -3.4 compare
L-Asparagine 10 mM (N) -0.8 -6.3 compare
L-Asparagine 10 mM (N) -0.8 -5.4 compare
L-Aspartic Acid 10 mM (N) -0.4 -3.1 compare
L-Aspartic Acid 10 mM (N) -0.4 -3.0 compare
L-Glutamic 10 mM (N) -0.4 -2.7 compare
L-Glutamic 10 mM (N) -0.5 -3.5 compare
L-Glutamine 10 mM (N) -0.6 -4.4 compare
L-Glutamine 10 mM (N) -0.5 -3.7 compare
L-Serine 10 mM (N) -0.1 -1.1 compare
L-Serine 10 mM (N) -0.2 -1.7 compare
L-Valine 10 mM (N) -0.4 -2.8 compare
L-Valine 10 mM (N) -0.4 -2.8 compare
no stress control no stress control -0.2 -1.7 compare
no stress control -0.3 -1.9 compare
no stress control -0.1 -0.4 compare
no stress control -0.1 -0.6 compare
no stress control -0.1 -0.7 compare
no stress control -0.3 -2.1 compare
no stress control -0.1 -0.8 compare
stress 7H9 with Bedaquiline 0.15 ug/mL -0.5 -3.2 compare
7H9 with Bedaquiline 0.15 ug/mL -0.5 -3.3 compare
7H9 with Clarithromycin 0.967 ug/mL -0.4 -3.1 compare
7H9 with Clarithromycin 0.967 ug/mL -0.3 -2.5 compare
7H9 with Clofazimine 0.072 ug/mL -0.3 -2.4 compare
7H9 with Clofazimine 0.072 ug/mL -0.4 -2.7 compare
7H9 with Clofazimine 0.45 ug/mL -0.5 -4.0 compare
7H9 with Clofazimine 0.45 ug/mL -0.4 -2.8 compare
7H9 with Delamanid 0.236 ug/mL -0.2 -1.7 compare
7H9 with Delamanid 0.236 ug/mL -0.3 -2.2 compare
7H9 with Dimethyl Sulfoxide 1 vol% -0.1 -0.8 compare
7H9 with Dimethyl Sulfoxide 1 vol% -0.0 -0.3 compare
7H9 with Ethambutol 0.75 ug/mL -0.8 -5.6 compare
7H9 with Ethambutol 0.75 ug/mL -0.9 -6.6 compare
7H9 with Ethionamide 0.1 ug/mL -0.4 -2.1 compare
7H9 with Ethionamide 0.1 ug/mL -0.4 -2.6 compare
7H9 with Hygromycin B 0.0095 mM -0.3 -2.1 compare
7H9 with Hygromycin B 0.0095 mM -0.2 -1.5 compare
7H9 with Isoniazid 0.025 ug/mL -0.6 -3.2 compare
7H9 with Isoniazid 0.025 ug/mL -0.6 -3.1 compare
7H9 with Levofloxacin 0.3 ug/mL -0.3 -1.9 compare
7H9 with Linezolid 0.44 ug/mL -0.2 -1.1 compare
7H9 with Meropenem 9.6 ug/mL -0.6 -4.4 compare
7H9 with Meropenem 9.6 ug/mL -0.9 -6.1 compare
7H9 with Moxifloxacin 0.121 ug/mL -0.1 -0.5 compare
7H9 with Moxifloxacin 0.121 ug/mL +0.0 +0.0 compare
7H9 with Ofloxacin 0.8 ug/mL -0.2 -1.4 compare
7H9 with Ofloxacin 0.8 ug/mL -0.1 -0.9 compare
7H9 with para-aminosalicylic 0.086 ug/mL -0.1 -0.6 compare
7H9 with para-aminosalicylic 0.086 ug/mL -0.2 -1.2 compare
7H9 with para-aminosalicylic 0.086 ug/mL -0.2 -1.2 compare
7H9 with Pretomanid 0.213 ug/mL -0.1 -0.8 compare
7H9 with Pretomanid 0.213 ug/mL -0.1 -0.4 compare
7H9 with Rifampicin 0.00045 ug/mL -0.4 -2.9 compare
7H9 with Rifampicin 0.00045 ug/mL -0.5 -3.3 compare
7H9 with Rifampicin 0.014 ug/mL -0.4 -3.0 compare
7H9 with Rifampicin 0.014 ug/mL -0.4 -2.9 compare
7H9 with Streptomycin 0.178 ug/mL -0.3 -2.0 compare
7H9 with Streptomycin 0.178 ug/mL -0.4 -2.6 compare
7H9 with Sulfamethizole 0.026 mM -0.2 -1.2 compare
7H9 with Sulfamethizole 0.026 mM -0.4 -2.5 compare
7H9 with Sulfaquinoxaline 0.097 mM -0.1 -0.6 compare