Fitness data for Rv3731 in Mycobacterium tuberculosis H37Rv

Possible ATP-dependent DNA ligase LigC (polydeoxyribonucleotide synthase [ATP]) (polynucleotide ligase [ATP]) (sealase) (DNA repair protein) (DNA joinase)
SEED: ATP-dependent DNA ligase (EC 6.5.1.1) LigC
KEGG: DNA ligase (ATP)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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group condition fitness t score  
stress 7H9 with Sisomicin 0.07 mM -0.7 -3.1 compare
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -0.4 -2.3 compare
pH pH 5.5 -0.3 -1.7 compare
stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.3 -1.8 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.3 -1.6 compare
no stress control no stress control -0.3 -1.8 compare
nitrogen source L-Alanine 10 mM (N) -0.3 -2.1 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.3 -1.6 compare
nitrogen source L-Valine 10 mM (N) -0.3 -1.5 compare
stress 7H9 with Nickel (II) chloride 0.6 mM -0.3 -1.6 compare
stress 7H9 with Delamanid 0.236 ug/mL -0.3 -1.6 compare
carbon source oleate 200uM (C) -0.3 -1.6 compare
no stress control no stress control -0.3 -1.1 compare
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM +0.3 +1.8 compare
stress 7H9 with Formaldehyde 0.23 mM +0.3 +1.7 compare
stress 7H9 with Menadione 0.005 mM +0.3 +1.3 compare
stress 7H9 with Menadione 0.005 mM +0.3 +1.5 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.3 +1.7 compare
stress 7H9 with Ethambutol 0.75 ug/mL +0.3 +2.2 compare
stress 7H9 with Plumbagin 0.01 mM +0.4 +3.0 compare