Fitness data for Rv3674c in Mycobacterium tuberculosis H37Rv

Probable endonuclease III Nth (DNA-(apurinic or apyrimidinic site)lyase) (AP lyase) (AP endonuclease class I) (endodeoxyribonuclease (apurinic or apyrimidinic)) (deoxyribonuclease (apurinic or apyrimidinic))
SEED: Endonuclease III (EC 4.2.99.18)
KEGG: endonuclease III

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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group condition fitness t score  
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.7 -3.1 compare
stress 7H9 with Sisomicin 0.07 mM -0.5 -1.6 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.5 -1.6 compare
pH pH 4.5 -0.5 -1.7 compare
stress 7H9 with Irgasan 0.065 mM -0.4 -2.3 compare
stress 7H9 with Cetrimonium bromide 0.015 vol% -0.4 -2.6 compare
nitrogen source L-Glutamine 10 mM (N) -0.4 -1.6 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.4 -1.6 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.4 -2.2 compare
pH pH 5.5 -0.4 -1.0 compare
nitrogen source Urea 10mM (N) -0.4 -1.5 compare
no stress control no stress control -0.3 -1.3 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM -0.3 -1.7 compare
nitrogen source Ammonium chloride 10mM (N) -0.3 -1.5 compare
stress 7H9 with Rifampicin 0.014 ug/mL -0.3 -1.8 compare
stress 7H9 with Linezolid 0.44 ug/mL -0.3 -1.5 compare
stress 7H9 with Benzethonium chloride 0.068 mM -0.3 -1.4 compare
stress 7H9 with Nickel (II) chloride 0.6 mM +0.3 +1.1 compare
stress 7H9 with Econazole nitrate salt 0.0082 mM +0.4 +1.3 compare
stress 7H9 with Geneticin G418 0.35 mM +0.4 +1.5 compare