Fitness data for Rv3571 in Mycobacterium tuberculosis H37Rv

Reductase component of 3-ketosteroid-9-alpha-hydroxylase KshB
SEED: Phenylacetate-CoA oxygenase/reductase, PaaK subunit

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
carbon source cholesterol 100uM (C) -2.0 -4.1 compare
carbon source cholesterol 100uM (C) -1.3 -4.3 compare
stress 7H9 with Sisomicin 0.07 mM -0.7 -1.9 compare
carbon source pyruvate (C) -0.6 -1.7 compare
stress 7H9 with Menadione 0.005 mM -0.6 -2.4 compare
stress 7H9 with copper (II) chloride 0.08 mM -0.5 -0.9 compare
stress 7H9 with Chloramphenicol 0.01 mM -0.5 -1.4 compare
stress 7H9 with Antimycin A 0.0186 mM -0.5 -1.6 compare
stress 7H9 with Benzethonium chloride 0.068 mM -0.4 -1.4 compare
stress 7H9 with Ethambutol 0.75 ug/mL -0.4 -2.0 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.4 -1.2 compare
stress 7H9 with Ofloxacin 0.8 ug/mL -0.4 -1.4 compare
pH pH 5.5 +0.4 +1.0 compare
carbon source Palmitic 100 uM (C) +0.4 +2.5 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.4 +1.7 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.4 +0.9 compare
nitrogen source L-Asparagine 10 mM (N) +0.4 +1.7 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.5 +2.1 compare
pH pH 5.5 +0.5 +2.1 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.7 +2.0 compare