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  • Fitness data for Rv3538 in Mycobacterium tuberculosis H37Rv

    Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase.
    SEED: Enoyl-CoA hydratase

    Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.9)


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    group condition fitness t score  
    no stress control no stress control -3.3 -1.7 compare
    pH pH 4.5 -1.5 -1.1 compare
    nitrogen source Ammonium chloride 10mM (N) -1.3 -0.7 compare
    stress 7H9 with Ethionamide 0.1 ug/mL -1.2 -1.0 compare
    no stress control no stress control -1.2 -1.0 compare
    no stress control no stress control -1.1 -0.9 compare
    no stress control no stress control -1.0 -1.1 compare
    stress 7H9 with Bedaquiline 0.15 ug/mL -1.0 -1.0 compare
    stress 7H9 with Erythromycin 0.016 mM -1.0 -1.3 compare
    stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -0.9 -1.0 compare
    stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.9 +1.4 compare
    nitrogen source Urea 10mM (N) +0.9 +1.2 compare
    stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM +0.9 +1.0 compare
    stress 7H9 with Antimycin A 0.0186 mM +0.9 +1.3 compare
    stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +1.0 +1.4 compare
    stress 7H9 with Cetrimonium bromide 0.015 vol% +1.0 +1.6 compare
    stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +1.0 +1.1 compare
    stress 7H9 with Dodecyl Sulfate 0.02 vol% +1.0 +1.3 compare
    stress 7H9 with Zinc Pyrithione 0.00072 mM +1.1 +1.5 compare
    stress 7H9 with Linezolid 0.44 ug/mL +1.2 +1.8 compare