Fitness data for Rv3509c in Mycobacterium tuberculosis H37Rv

Probable acetohydroxyacid synthase IlvX (acetolactate synthase)
SEED: Acetolactate synthase large subunit (EC 2.2.1.6)
KEGG: acetolactate synthase I/II/III large subunit

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
stress 7H9 with Sisomicin 0.07 mM -0.8 -3.6 compare
stress 7H9 with Geneticin G418 0.35 mM -0.6 -3.2 compare
stress 7H9 with nitrate 4 mM -0.5 -2.4 compare
stress 7H9 with Novobiocin 0.004 mM -0.5 -2.5 compare
no stress control no stress control -0.4 -2.6 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.4 -2.6 compare
stress 7H9 with nitrite 3 mM; pH 5.5 +0.4 +2.1 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.4 +2.5 compare
stress 7H9 with Ofloxacin 0.8 ug/mL +0.4 +2.6 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.5 +3.1 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.5 +3.2 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.5 +3.4 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +0.5 +2.9 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.6 +3.5 compare
stress 7H9 with Ofloxacin 0.8 ug/mL +0.6 +3.7 compare
no stress control no stress control +0.6 +3.8 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.6 +3.9 compare
no stress control no stress control +0.7 +4.3 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.7 +5.0 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.7 +4.5 compare