Fitness data for Rv3476c in Mycobacterium tuberculosis H37Rv

Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter)
SEED: dicarboxylic acid transporter PcaT
KEGG: MFS transporter, MHS family, alpha-ketoglutarate permease

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)


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group condition fitness t score  
stress 7H9 with Sisomicin 0.07 mM -0.3 -2.0 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.3 -1.1 compare
pH pH 4.5 -0.3 -1.3 compare
carbon source oleate 200uM (C) -0.3 -1.4 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.2 -1.1 compare
stress 7H9 with Cloxacillin 0.0386 mM +0.2 +1.5 compare
stress 7H9 with Rifampicin 0.014 ug/mL +0.3 +1.8 compare
stress 7H9 with Hygromycin B 0.0095 mM +0.3 +1.3 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.3 +1.6 compare
stress 7H9 with Benzethonium chloride 0.068 mM +0.3 +1.7 compare
nitrogen source L-Glutamine 10 mM (N) +0.3 +1.6 compare
stress 7H9 with Clofazimine 0.45 ug/mL +0.3 +2.4 compare
pH pH 5.5 +0.3 +1.9 compare
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM +0.3 +1.8 compare
stress 7H9 with Dibucaine 0.21 mM +0.4 +2.0 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM +0.4 +1.8 compare
stress 7H9 with Plumbagin 0.01 mM +0.4 +2.3 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM +0.4 +2.3 compare
stress 7H9 with Sisomicin 0.07 mM +0.5 +2.2 compare
no stress control no stress control +0.5 +2.1 compare