Fitness data for Rv3470c in Mycobacterium tuberculosis H37Rv

Probable acetolactate synthase (large subunit) IlvB2 (AHAS) (acetohydroxy-acid synthase large subunit) (ALS)
SEED: Acetolactate synthase large subunit (EC 2.2.1.6)
KEGG: acetolactate synthase I/II/III large subunit

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
stress 7H9 with Linezolid 0.44 ug/mL -0.5 -1.8 compare
carbon source oleate 200uM (C) -0.5 -2.0 compare
carbon source cholesterol 100uM (C) -0.4 -2.1 compare
carbon source pyruvate (C) -0.4 -2.1 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 -1.9 compare
nitrogen source Urea 10mM (N) -0.4 -1.8 compare
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -0.4 -1.6 compare
stress 7H9 with Menadione 0.005 mM -0.4 -1.9 compare
stress 7H9 with Chlorpromazine 0.054 mM +0.4 +0.9 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.4 +2.2 compare
stress 7H9 with hypochlorite 0.4 vol% +0.4 +1.4 compare
stress 7H9 with Erythromycin 0.016 mM +0.4 +2.1 compare
stress 7H9 with Hydrogen peroxide 3.97 mM +0.4 +1.9 compare
no stress control no stress control +0.4 +1.4 compare
stress 7H9 with Meropenem 9.6 ug/mL +0.4 +2.2 compare
stress 7H9 with Geneticin G418 0.35 mM +0.5 +1.9 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM +0.5 +1.7 compare
stress 7H9 with nitrite 5 mM +0.5 +2.0 compare
stress 7H9 with Erythromycin 0.016 mM +0.6 +2.7 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.7 +2.6 compare