Fitness data for Rv3469c in Mycobacterium tuberculosis H37Rv

Probable 4-hydroxy-2-oxovalerate aldolase MhpE (HOA)
SEED: 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.39)
KEGG: 4-hydroxy 2-oxovalerate aldolase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
stress 7H9 with methylglyoxal 1.2 mM -0.7 -2.4 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.7 -2.9 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.6 -3.4 compare
stress 7H9 with Chlorpromazine 0.054 mM -0.6 -1.9 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.6 -2.2 compare
stress 7H9 with Antimycin A 0.0186 mM -0.6 -2.8 compare
no stress control no stress control -0.6 -1.8 compare
stress 7H9 with Ramoplanin 0.009 mM -0.6 -2.5 compare
stress 7H9 with methylglyoxal 1.2 mM -0.5 -2.5 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.5 -1.3 compare
no stress control no stress control -0.5 -1.4 compare
nitrogen source L-Glutamine 10 mM (N) +0.5 +1.8 compare
no stress control no stress control +0.5 +1.6 compare
stress 7H9 with Hydrogen peroxide 3.97 mM +0.5 +2.5 compare
carbon source Palmitic 100 uM (C) +0.6 +2.1 compare
no stress control no stress control +0.6 +2.4 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.7 +2.0 compare
stress 7H9 with Plumbagin 0.01 mM +0.7 +2.8 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.9 +1.5 compare
stress 7H9 with Sisomicin 0.07 mM +1.3 +3.0 compare