Fitness data for Rv3463 in Mycobacterium tuberculosis H37Rv

Conserved protein
SEED: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.4 -2.1 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.4 -2.0 compare
pH pH 5.5 -0.4 -2.0 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 -1.7 compare
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -0.4 -1.4 compare
nitrogen source L-Asparagine 10 mM (N) -0.4 -2.4 compare
no stress control no stress control -0.4 -2.0 compare
pH pH 4.5 -0.4 -1.9 compare
stress 7H9 with copper (II) chloride 0.08 mM -0.4 -1.6 compare
stress 7H9 with Erythromycin 0.016 mM -0.4 -1.6 compare
stress 7H9 with Ramoplanin 0.009 mM +0.4 +1.8 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.4 +2.4 compare
stress 7H9 with Chloramphenicol 0.01 mM +0.4 +1.6 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.4 +1.8 compare
stress 7H9 with Ethambutol 0.75 ug/mL +0.4 +1.5 compare
carbon source Palmitic 100 uM (C) +0.4 +2.3 compare
stress 7H9 with Thioridazine 0.028 mM +0.4 +2.4 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.4 +1.5 compare
carbon source oleate 200uM (C) +0.5 +2.4 compare
carbon source cholesterol 100uM (C) +0.5 +2.0 compare