Fitness data for Rv3419c in Mycobacterium tuberculosis H37Rv

Probable O-sialoglycoprotein endopeptidase Gcp (glycoprotease)
SEED: TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA
KEGG: O-sialoglycoprotein endopeptidase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.6)


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group condition fitness t score  
pH pH 4.5 -2.9 -2.1 compare
carbon source cholesterol 100uM (C) -2.8 -2.1 compare
pH pH 5.5 -2.7 -2.5 compare
pH pH 4.5 -2.5 -2.1 compare
no stress control no stress control -2.3 -2.0 compare
stress 7H9 with Formaldehyde 0.23 mM -2.1 -1.9 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -2.0 -1.7 compare
stress 7H9 with hypochlorite 0.4 vol% -2.0 -1.5 compare
stress 7H9 with Isoniazid 0.025 ug/mL -1.9 -1.5 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -1.9 -2.0 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.8 -1.7 compare
no stress control no stress control -1.7 -1.9 compare
stress 7H9 with methylglyoxal 1.2 mM -1.7 -1.6 compare
carbon source Palmitic 100 uM (C) -1.6 -2.4 compare
carbon source D-Glucose (C) -1.6 -2.4 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +1.6 +3.2 compare
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM +1.6 +3.0 compare
stress 7H9 with Lomefloxacin 0.0035 mM +1.7 +2.1 compare
stress 7H9 with Rifampicin 0.014 ug/mL +1.8 +3.2 compare
stress 7H9 with Rifampicin 0.014 ug/mL +1.9 +2.4 compare