Fitness data for Rv3343c in Mycobacterium tuberculosis H37Rv

PPE family protein PPE54
SEED: (MTV016.43c), len: 2523. Member of PPE-family of M. tuberculosis proteins, Gly-, Asn-rich MPTR subgroup. Most similar to MTV004_5 (3716 aa). FASTA scores: gp|AL0091|MTV004_5 Mycobacterium tuberculosis sequence (3716 aa)opt: 4672 z-score: 3736.8 E(): 0; 44.2% identity in 3174 aaoverlap. Also similar to MTV004_3, MTCY63_9, MTY13E10_17,MTY13E10_16, MTCY180_1, MTV050_1, MTCY3C7_23, MTV014_3, MTCY63_10 etc. TBparse score is 0.923

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)


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group condition fitness t score  
stress 7H9 with Ethambutol 0.75 ug/mL -0.3 -2.9 compare
stress 7H9 with Sisomicin 0.07 mM -0.3 -2.3 compare
stress 7H9 with nitrate 4 mM -0.3 -2.1 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.3 -2.0 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.2 +2.1 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +0.3 +2.1 compare
no stress control no stress control +0.3 +2.3 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.3 +2.1 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +0.3 +2.5 compare
stress 7H9 with nitrite 3 mM; pH 5.5 +0.3 +2.5 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.3 +2.7 compare
no stress control no stress control +0.3 +2.6 compare
no stress control no stress control +0.3 +2.8 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.3 +2.5 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.4 +2.8 compare
no stress control no stress control +0.4 +2.7 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.4 +3.1 compare
stress 7H9 with Ofloxacin 0.8 ug/mL +0.4 +2.7 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.4 +3.1 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.4 +3.3 compare