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  • Fitness data for Rv3287c in Mycobacterium tuberculosis H37Rv

    Anti-sigma factor RsbW (sigma negative effector)
    SEED: Serine-protein kinase RsbW (EC 2.7.11.1)

    Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.2)


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    group condition fitness t score  
    stress 7H9 with Ethionamide 0.1 ug/mL -1.7 -1.3 compare
    stress 7H9 with nitrate 4 mM -1.7 -0.8 compare
    stress 7H9 with Delamanid 0.236 ug/mL -1.7 -1.5 compare
    carbon source Stearic 100 uM (C) -1.5 -1.1 compare
    carbon source L-Aspartic Acid (C) -1.5 -1.4 compare
    pH pH 5.5 -1.5 -0.6 compare
    stress 7H9 with Clarithromycin 0.967 ug/mL -1.4 -1.5 compare
    nitrogen source L-Valine 10 mM (N) -1.4 -1.2 compare
    nitrogen source L-Aspartic Acid 10 mM (N) -1.4 -1.2 compare
    stress 7H9 with Nickel (II) chloride 0.6 mM -1.4 -1.1 compare
    no stress control no stress control -1.3 -0.5 compare
    stress 7H9 with Linezolid 0.44 ug/mL -1.3 -1.1 compare
    stress 7H9 with Vancomycin Hydrochloride from Streptomyces orientalis 0.012 mM -1.3 -1.1 compare
    stress 7H9 with Lomefloxacin 0.0035 mM -1.2 -1.4 compare
    stress 7H9 with Dicloxacillin 0.0069 mM -1.2 -1.4 compare
    stress 7H9 with EDTA (disodium salt) 0.2 mM +1.2 +1.3 compare
    stress 7H9 with Pretomanid 0.213 ug/mL +1.5 +0.9 compare
    pH pH 4.5 +1.5 +1.0 compare
    stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +1.5 +1.8 compare
    pH pH 4.5 +2.2 +1.5 compare