Fitness data for Rv3262 in Mycobacterium tuberculosis H37Rv

Probable F420 biosynthesis protein FbiB
SEED: Coenzyme F420-0:L-glutamate ligase @ Coenzyme F420-1:L-glutamate ligase / domain of unknown function
KEGG: coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.3)


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group condition fitness t score  
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -3.5 -2.4 compare
pH pH 4.5 -2.4 -2.7 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -2.0 -1.8 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -2.0 -2.5 compare
nitrogen source Urea 10mM (N) -1.7 -2.1 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM -1.5 -2.0 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM -1.5 -1.7 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -1.4 -1.2 compare
no stress control no stress control -1.4 -1.7 compare
no stress control no stress control -1.3 -1.0 compare
stress 7H9 with methylglyoxal 1.2 mM -1.3 -1.8 compare
stress 7H9 with Plumbagin 0.01 mM -1.3 -1.8 compare
stress 7H9 with Tetrazolium violet 0.065 mM -1.3 -1.7 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.3 +2.1 compare
stress 7H9 with Phenazine ethosulfate 0.0137 mM +1.3 +2.4 compare
stress 7H9 with Delamanid 0.236 ug/mL +1.7 +5.2 compare
stress 7H9 with Delamanid 0.236 ug/mL +2.0 +4.9 compare
stress 7H9 with Antimycin A 0.0186 mM +2.4 +3.8 compare
stress 7H9 with Pretomanid 0.213 ug/mL +2.9 +11.0 compare
stress 7H9 with Pretomanid 0.213 ug/mL +3.6 +8.5 compare