Fitness data for Rv3261 in Mycobacterium tuberculosis H37Rv

Probable F420 biosynthesis protein FbiA
SEED: Lactyl (2) diphospho-(5')guanosine:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase
KEGG: LPPG:FO 2-phospho-L-lactate transferase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.0)


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group condition fitness t score  
stress 7H9 with Plumbagin 0.01 mM -3.1 -4.5 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -2.6 -4.7 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -1.9 -3.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -1.4 -2.5 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -1.4 -2.5 compare
no stress control no stress control -1.2 -2.2 compare
stress 7H9 with Amikacin di2 ug/mL -1.2 -2.9 compare
no stress control no stress control -1.1 -2.5 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -1.1 -2.5 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM -1.1 -1.6 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -1.0 -2.2 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -1.0 -2.3 compare
stress 7H9 with Ethionamide 0.1 ug/mL +1.0 +2.6 compare
pH pH 4.5 +1.0 +2.0 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.3 +3.2 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.7 +6.3 compare
stress 7H9 with Delamanid 0.236 ug/mL +1.8 +7.0 compare
stress 7H9 with Delamanid 0.236 ug/mL +2.0 +5.4 compare
stress 7H9 with Pretomanid 0.213 ug/mL +3.5 +8.3 compare
stress 7H9 with Pretomanid 0.213 ug/mL +4.7 +13.4 compare