Fitness data for Rv3237c in Mycobacterium tuberculosis H37Rv

Conserved protein
SEED: Potassium channel TrkA, possible KefG analog required for KefB activity
KEGG: TrkA domain protein

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.7)


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group condition fitness t score  
stress 7H9 with Ethionamide 0.1 ug/mL -1.2 -2.5 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -1.0 -2.1 compare
pH pH 4.5 -1.0 -2.0 compare
no stress control no stress control -0.9 -3.5 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.9 -2.2 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.8 -2.5 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.8 -1.9 compare
no stress control no stress control -0.8 -2.2 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.8 -2.5 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.8 -2.4 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.8 -2.3 compare
no stress control no stress control -0.8 -3.5 compare
stress 7H9 with Hygromycin B 0.0095 mM -0.8 -2.3 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.8 -2.3 compare
stress 7H9 with Streptomycin 0.178 ug/mL -0.8 -2.0 compare
stress 7H9 with Chloramphenicol 0.01 mM -0.8 -2.2 compare
pH 7H9 pH 5.5 -0.8 -4.2 compare
stress 7H9 with Delamanid 0.236 ug/mL -0.7 -3.7 compare
pH pH 4.5 -0.7 -1.5 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.7 -1.4 compare