Fitness data for Rv3045 in Mycobacterium tuberculosis H37Rv

Probable NADP-dependent alcohol dehydrogenase AdhC
SEED: Alcohol dehydrogenase (EC 1.1.1.1)
KEGG: uncharacterized zinc-type alcohol dehydrogenase-like protein

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.9)


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group condition fitness t score  
stress 7H9 with Sisomicin 0.07 mM -3.3 -3.4 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -2.3 -4.3 compare
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -2.1 -2.7 compare
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -1.8 -2.2 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.6 -2.2 compare
no stress control no stress control -1.4 -2.0 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.4 -2.1 compare
stress 7H9 with Bedaquiline 0.15 ug/mL -1.3 -2.5 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM -1.2 -2.3 compare
stress 7H9 with Clofazimine 0.45 ug/mL -1.2 -2.9 compare
carbon source L-Lactate 10 mM (C) -1.2 -3.5 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -1.1 -2.3 compare
stress 7H9 with Bedaquiline 0.15 ug/mL -1.1 -3.3 compare
carbon source propionate (C) -1.1 -4.3 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -1.0 -2.6 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM -1.0 -1.8 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM -0.9 -2.4 compare
stress 7H9 with Amikacin di2 ug/mL -0.9 -2.2 compare
stress 7H9 with methylglyoxal 1.2 mM -0.9 -1.5 compare
pH pH 4.5 +1.4 +3.6 compare