Fitness data for Rv2993c in Mycobacterium tuberculosis H37Rv

Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase)
SEED: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) / 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.0)


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group condition fitness t score  
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.9 -1.8 compare
stress 7H9 with nitrite 3 mM; pH 5.5 -1.6 -2.1 compare
pH pH 5.5 -1.6 -1.6 compare
stress 7H9 with Linezolid 0.3 ug/mL -1.2 -1.8 compare
stress 7H9 with Sisomicin 0.07 mM -1.1 -0.8 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -1.1 -1.4 compare
carbon source D-Lactate 10 mM (C) -1.0 -1.0 compare
no stress control no stress control -1.0 -1.6 compare
nitrogen source Urea 10mM (N) -1.0 -1.4 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM +1.0 +2.5 compare
stress 7H9 with nitrite 5 mM +1.0 +1.8 compare
carbon source Glycerol (C) +1.0 +1.8 compare
pH 7H9 pH 5.5 +1.0 +1.9 compare
stress 7H9 with Clarithromycin 0.967 ug/mL +1.0 +1.2 compare
stress 7H9 with Econazole nitrate salt 0.0082 mM +1.1 +3.1 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +1.1 +2.2 compare
stress 7H9 with Sulfamethizole 0.026 mM +1.1 +2.2 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +1.1 +2.9 compare
no stress control no stress control +1.2 +1.3 compare
stress 7H9 with Cetrimonium bromide 0.015 vol% +1.6 +4.8 compare