Fitness data for Rv2947c in Mycobacterium tuberculosis H37Rv

Probable polyketide synthase Pks15
SEED: (MTCY24G1.02), len: 496 aa, Probable polyketide synthase, almost identical to G560508 PKS002B (495 aa), fasta scores, opt: 3270, E(): 0, (99.6% identity in 496 aa overlap); contains PS00606 Beta-ketoacyl synthases active site; similar to MTCY338.20 (49.9% identity in 465 aa overlap) and MTCY24G1.09 (50.2% identity in 454 aa overlap) and MTCY22H8.03 (47.6% identity in 437 aa overlap)
KEGG: polyketide synthase 1/15

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)


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group condition fitness t score  
stress 7H9 with nitrite 2.5 mM -0.4 -2.5 compare
carbon source heptadecanoic 250 uM (C) -0.3 -2.5 compare
carbon source acetate (C) -0.3 -2.3 compare
carbon source Palmitic 100 uM (C) -0.3 -1.9 compare
stress 7H9 with Erythromycin 0.016 mM -0.2 -1.8 compare
stress 7H9 with Erythromycin 0.016 mM -0.2 -1.7 compare
carbon source propionate (C) -0.2 -1.5 compare
stress 7H9 with Clarithromycin 0.967 ug/mL -0.2 -1.6 compare
carbon source Palmitic 100 uM (C) -0.2 -1.5 compare
stress 7H9 with Rifampicin 0.00045 ug/mL -0.2 -1.6 compare
carbon source butyrate 10 mM (C) -0.2 -1.4 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -0.2 -1.2 compare
stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.2 -1.3 compare
stress 7H9 with Clofazimine 0.45 ug/mL +0.2 +1.3 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.2 +1.0 compare
stress 7H9 with Tetracycline 0.0058 mM +0.2 +1.3 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.2 +1.4 compare
carbon source cholesterol 100uM (C) +0.2 +1.3 compare
stress 7H9 with methylglyoxal 1.2 mM +0.2 +1.5 compare
nitrogen source Urea 10mM (N) +0.3 +1.8 compare