Fitness data for Rv2877c in Mycobacterium tuberculosis H37Rv

Probable conserved integral membrane protein
SEED: 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)


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group condition fitness t score  
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.3 -2.1 compare
stress 7H9 with Linezolid 0.44 ug/mL -0.3 -1.9 compare
stress 7H9 with Sisomicin 0.07 mM -0.2 -1.7 compare
stress 7H9 with Nickel (II) chloride 0.6 mM -0.2 -1.7 compare
carbon source acetate (C) -0.2 -1.9 compare
carbon source acetate (C) -0.2 -1.9 compare
stress 7H9 with Antimycin A 0.0186 mM -0.2 -1.6 compare
stress 7H9 with Chlorpromazine 0.054 mM -0.2 -1.3 compare
no stress control no stress control -0.2 -1.4 compare
stress 7H9 with Econazole nitrate salt 0.0082 mM -0.2 -1.4 compare
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -0.2 -1.4 compare
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -0.2 -1.4 compare
no stress control no stress control -0.2 -1.2 compare
stress 7H9 with Ramoplanin 0.009 mM -0.2 -1.2 compare
stress 7H9 with Erythromycin 0.016 mM -0.2 -1.1 compare
pH 7H9 pH 5.5 -0.2 -1.3 compare
no stress control no stress control -0.2 -1.3 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.2 +1.2 compare
no stress control no stress control +0.2 +1.0 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.2 +1.1 compare