Fitness data for Rv2793c in Mycobacterium tuberculosis H37Rv

Probable tRNA pseudouridine synthase B TruB (tRNA pseudouridine 55 synthase) (PSI55 synthase) (pseudouridylate synthase) (uracil hydrolyase)
SEED: tRNA pseudouridine synthase B (EC 4.2.1.70)
KEGG: tRNA pseudouridine synthase B

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.2)


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group condition fitness t score  
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -2.4 -1.4 compare
no stress control no stress control -2.3 -1.3 compare
stress 7H9 with Linezolid 0.3 ug/mL -2.1 -1.2 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL -1.7 -1.9 compare
no stress control no stress control -1.6 -1.1 compare
stress 7H9 with Amikacin di2 ug/mL -1.4 -1.1 compare
pH pH 4.5 -1.4 -0.9 compare
no stress control no stress control -1.4 -1.2 compare
carbon source cholesterol 100uM (C) -1.3 -1.1 compare
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -1.3 -1.0 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -1.3 -1.0 compare
nitrogen source L-Serine 10 mM (N) -1.3 -1.6 compare
stress 7H9 with Benzethonium chloride 0.068 mM -1.2 -1.1 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +1.2 +1.4 compare
stress 7H9 with Pretomanid 0.213 ug/mL +1.3 +2.8 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.3 +2.2 compare
stress 7H9 with Menadione 0.005 mM +1.5 +1.3 compare
stress 7H9 with Sisomicin 0.07 mM +1.6 +1.5 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.7 +2.0 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +1.7 +2.6 compare