Fitness data for Rv2589 in Mycobacterium tuberculosis H37Rv

4-aminobutyrate aminotransferase GabT (gamma-amino-N-butyrate transaminase) (GABA transaminase) (glutamate:succinic semialdehyde transaminase) (GABA aminotransferase) (GABA-at)
SEED: Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19)
KEGG: 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
pH pH 4.5 -1.6 -8.8 compare
pH pH 4.5 -1.5 -7.2 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.0 -5.9 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.9 -5.3 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.8 -5.5 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.7 -4.4 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.7 -4.4 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.7 -4.1 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.7 -4.1 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.6 -3.4 compare
pH 7H9 pH 5.5 -0.6 -3.7 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.5 -3.1 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.5 -3.5 compare
stress 7H9 with Geneticin G418 0.35 mM -0.5 -3.6 compare
stress 7H9 with nitrite 3 mM; pH 5.5 -0.5 -3.5 compare
stress 7H9 with Geneticin G418 0.35 mM -0.5 -2.8 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.4 -2.6 compare
stress 7H9 with Sulfaquinoxaline 0.097 mM -0.4 -2.7 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.4 +2.2 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.4 +2.5 compare