Fitness data for Rv2583c in Mycobacterium tuberculosis H37Rv

Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase)
SEED: GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I
KEGG: GTP pyrophosphokinase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.2)


Add gene:

Or see all 236 experiments or choose conditions

group condition fitness t score  
carbon source propionate (C) -1.9 -2.8 compare
carbon source propionate (C) -1.8 -4.9 compare
stress 7H9 with Plumbagin 0.01 mM -1.5 -3.5 compare
stress 7H9 with Irgasan 0.065 mM -1.3 -2.4 compare
stress 7H9 with Clofazimine 0.072 ug/mL -1.2 -3.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.2 -1.9 compare
stress 7H9 with Sulfamethizole 0.026 mM +1.3 +2.8 compare
stress 7H9 with Pretomanid 0.213 ug/mL +1.3 +4.3 compare
stress 7H9 with Hygromycin B 0.0095 mM +1.4 +3.8 compare
stress 7H9 with Clarithromycin 0.967 ug/mL +1.4 +3.0 compare
stress 7H9 with Lomefloxacin 0.0035 mM +1.4 +3.4 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +1.6 +4.3 compare
stress 7H9 with Ethionamide 0.1 ug/mL +1.6 +3.8 compare
nitrogen source L-Glutamic 10 mM (N) +1.6 +5.4 compare
stress 7H9 with Clarithromycin 0.967 ug/mL +1.8 +3.1 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +2.2 +5.0 compare
nitrogen source L-Glutamic 10 mM (N) +2.2 +5.0 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +2.5 +7.8 compare
stress 7H9 with Isoniazid 0.025 ug/mL +3.0 +4.9 compare
stress 7H9 with Isoniazid 0.025 ug/mL +3.0 +6.9 compare