Fitness data for Rv2501c in Mycobacterium tuberculosis H37Rv

Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA1: biotin carboxylase + biotin carboxyl carrier protein (BCCP)
SEED: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
KEGG: acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
no stress control no stress control -0.9 -1.7 compare
stress 7H9 with Pretomanid 0.213 ug/mL -0.7 -2.1 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.7 -2.1 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.6 -2.5 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.6 -1.9 compare
stress 7H9 with Nickel (II) chloride 0.6 mM -0.6 -1.9 compare
stress 7H9 with Irgasan 0.065 mM -0.5 -1.3 compare
no stress control no stress control -0.5 -2.0 compare
stress 7H9 with Ethambutol 0.75 ug/mL -0.5 -1.8 compare
stress 7H9 with Cetrimonium bromide 0.015 vol% -0.5 -1.3 compare
carbon source propionate (C) -0.5 -1.3 compare
carbon source propionate (C) -0.5 -2.3 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM +0.5 +1.3 compare
carbon source acetate (C) +0.5 +2.2 compare
nitrogen source L-Aspartic Acid 10 mM (N) +0.5 +2.7 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.6 +1.7 compare
stress 7H9 with Ofloxacin 0.8 ug/mL +0.6 +1.5 compare
carbon source butyrate 10 mM (C) +0.7 +1.7 compare
nitrogen source L-Glutamic 10 mM (N) +0.8 +2.2 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.0 +1.9 compare