Fitness data for Rv2498c in Mycobacterium tuberculosis H37Rv

Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase)
SEED: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
KEGG: citrate lyase subunit beta / citryl-CoA lyase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
no stress control no stress control -0.8 -4.1 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.8 -2.6 compare
stress 7H9 with Chlorpromazine 0.054 mM -0.7 -3.0 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.7 -2.5 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.7 -2.2 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.6 -2.3 compare
stress 7H9 with nitrite 2.5 mM -0.6 -2.0 compare
stress 7H9 with Ramoplanin 0.009 mM -0.6 -1.8 compare
stress 7H9 with Geneticin G418 0.35 mM -0.5 -2.2 compare
no stress control no stress control -0.5 -2.6 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM -0.5 -2.0 compare
no stress control no stress control -0.5 -1.1 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.5 -2.5 compare
no stress control no stress control -0.5 -2.0 compare
no stress control no stress control -0.5 -2.2 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.5 -1.9 compare
stress 7H9 with Amikacin di2 ug/mL -0.5 -2.1 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -0.5 -2.2 compare
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -0.4 -2.1 compare
carbon source acetate (C) +0.5 +3.2 compare