Fitness data for Rv2483c in Mycobacterium tuberculosis H37Rv

Possible transmembrane phospholipid biosynthesis bifunctional enzyme PlsC: putative L-3-phosphoserine phosphatase (O-phosphoserine phosphohydrolase) (PSP) (pspase) + 1-acyl-SN-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (lysophosphatidic acid acyltransferase) (LPAAT)
SEED: Phosphoserine phosphatase (EC 3.1.3.3) / 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)
KEGG: 1-acyl-sn-glycerol-3-phosphate acyltransferase ; phosphoserine phosphatase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
stress 7H9 with Ramoplanin 0.009 mM -0.6 -2.2 compare
stress 7H9 with Rifampicin 0.014 ug/mL -0.5 -2.0 compare
nitrogen source Urea 10mM (N) -0.5 -2.0 compare
stress 7H9 with Rifampicin 0.014 ug/mL -0.5 -1.9 compare
nitrogen source Ammonium chloride 10mM (N) -0.5 -1.7 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.4 -1.5 compare
stress 7H9 with methylglyoxal 1.2 mM -0.4 -1.9 compare
no stress control no stress control -0.4 -1.3 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 -1.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.4 -2.2 compare
stress 7H9 with Nickel (II) chloride 0.6 mM -0.4 -1.9 compare
stress 7H9 with copper (II) chloride 0.08 mM -0.4 -1.2 compare
nitrogen source Ammonium chloride 10mM (N) -0.4 -2.1 compare
stress 7H9 with Formaldehyde 0.23 mM -0.4 -1.8 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM -0.4 -1.7 compare
stress 7H9 with Plumbagin 0.01 mM +0.4 +2.0 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.5 +1.9 compare
carbon source heptadecanoic 250 uM (C) +0.5 +1.7 compare
carbon source Stearic 100 uM (C) +0.5 +2.3 compare
carbon source Stearic 100 uM (C) +0.5 +2.4 compare