Fitness data for Rv2427c in Mycobacterium tuberculosis H37Rv

Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase)
SEED: Gamma-glutamyl phosphate reductase (EC 1.2.1.41)
KEGG: glutamate-5-semialdehyde dehydrogenase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
stress 7H9 with Isoniazid 0.025 ug/mL -1.2 -3.7 compare
stress 7H9 with nitrite 3 mM; pH 5.5 -1.0 -3.7 compare
pH pH 4.5 -1.0 -2.8 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.9 -2.2 compare
carbon source propionate (C) -0.8 -2.4 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM -0.7 -3.1 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.7 -2.0 compare
carbon source propionate (C) -0.7 -3.6 compare
no stress control no stress control -0.7 -1.7 compare
pH pH 4.5 -0.7 -2.1 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.6 -2.6 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.6 -2.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.5 -1.8 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM +0.5 +2.0 compare
nitrogen source L-Asparagine 10 mM (N) +0.5 +2.0 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.6 +2.2 compare
stress 7H9 with Novobiocin 0.004 mM +0.6 +2.3 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.6 +2.1 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.7 +2.7 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.8 +2.5 compare