Fitness data for Rv2427c in Mycobacterium tuberculosis H37Rv
Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase)
SEED: Gamma-glutamyl phosphate reductase (EC 1.2.1.41)
KEGG: glutamate-5-semialdehyde dehydrogenase
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)
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| group | condition | fitness | t score | |
|---|---|---|---|---|
| stress | 7H9 with Isoniazid 0.025 ug/mL | -1.2 | -3.6 | compare |
| stress | 7H9 with Isoniazid 0.025 ug/mL | -0.9 | -2.2 | compare |
| carbon source | propionate (C) | -0.8 | -2.4 | compare |
| stress | 7H9 with Ethionamide 0.1 ug/mL | -0.7 | -2.0 | compare |
| carbon source | propionate (C) | -0.7 | -3.7 | compare |
| stress | 7H9 with Ethionamide 0.1 ug/mL | -0.6 | -2.4 | compare |
| carbon source | D-Lactate 10 mM (C) | -0.4 | -1.7 | compare |
| carbon source | casaminos 1 mg/mL (C) | -0.3 | -1.5 | compare |
| nitrogen source | L-Asparagine 10 mM (N) | +0.3 | +2.1 | compare |
| carbon source | butyrate 10 mM (C) | +0.3 | +1.5 | compare |
| stress | 7H9 with Clofazimine 0.45 ug/mL | +0.3 | +1.7 | compare |
| carbon source | L-Glutamine (C) | +0.4 | +1.8 | compare |
| nitrogen source | L-Aspartic Acid 10 mM (N) | +0.4 | +2.2 | compare |
| nitrogen source | L-Aspartic Acid 10 mM (N) | +0.4 | +2.4 | compare |
| nitrogen source | Glycine 10 mM (N) | +0.4 | +1.8 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | +0.4 | +1.6 | compare |
| stress | 7H9 with Rifampicin 0.014 ug/mL | +0.4 | +1.8 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | +0.5 | +1.9 | compare |
| stress | 7H9 with Meropenem 9.6 ug/mL | +0.5 | +1.6 | compare |
| nitrogen source | L-Asparagine 10 mM (N) | +0.5 | +1.9 | compare |