Fitness data for Rv2388c in Mycobacterium tuberculosis H37Rv

Probable oxygen-independent coproporphyrinogen III oxidase HemN (coproporphyrinogenase) (coprogen oxidase)
SEED: Hypothetical radical SAM family enzyme in heat shock gene cluster, similarity with CPO of BS HemN-type
KEGG: oxygen-independent coproporphyrinogen III oxidase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)


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group condition fitness t score  
pH pH 4.5 -0.5 -3.0 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -0.4 -2.3 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.4 -1.9 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.4 -2.3 compare
stress 7H9 with Chloramphenicol 0.01 mM -0.3 -1.6 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.3 -1.9 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.3 -1.9 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -0.3 -1.9 compare
stress 7H9 with Lomefloxacin 0.0035 mM -0.3 -1.6 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -0.3 -1.5 compare
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -0.3 -1.8 compare
nitrogen source L-Aspartic Acid 10 mM (N) +0.3 +1.8 compare
stress 7H9 with copper (II) chloride 0.08 mM +0.3 +1.3 compare
nitrogen source Glycine 10 mM (N) +0.3 +1.7 compare
nitrogen source Glycine 10 mM (N) +0.3 +2.4 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.4 +1.8 compare
stress 7H9 with Rifampicin 0.014 ug/mL +0.4 +2.3 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.5 +2.3 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.1 +6.0 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.1 +5.4 compare