Fitness data for Rv2384 in Mycobacterium tuberculosis H37Rv

Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase
KEGG: mycobactin salicyl-AMP ligase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.9)


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group condition fitness t score  
stress 7H9 with Spectinomycin 0.029 mM -2.4 -2.6 compare
stress 7H9 with Sisomicin 0.07 mM -2.1 -2.2 compare
no stress control no stress control -1.6 -2.1 compare
stress 7H9 with Geneticin G418 0.35 mM -1.5 -1.9 compare
no stress control no stress control -1.4 -1.5 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -1.2 -1.4 compare
nitrogen source L-Glutamine 10 mM (N) -1.1 -2.6 compare
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -1.1 -1.3 compare
no stress control no stress control -1.1 -1.6 compare
stress 7H9 with Chlorpromazine 0.054 mM -0.9 -1.4 compare
no stress control no stress control -0.9 -1.3 compare
stress 7H9 with Linezolid 0.44 ug/mL -0.9 -1.4 compare
stress 7H9 with Tetrazolium violet 0.065 mM -0.9 -1.4 compare
carbon source propionate (C) -0.9 -1.9 compare
stress 7H9 with Cloxacillin 0.0386 mM -0.9 -1.4 compare
no stress control no stress control +0.9 +1.2 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +1.0 +1.8 compare
stress 7H9 with Lomefloxacin 0.0035 mM +1.1 +2.1 compare
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +1.1 +1.9 compare
no stress control no stress control +1.1 +1.8 compare