Fitness data for Rv2382c in Mycobacterium tuberculosis H37Rv

Polyketide synthetase MbtC (polyketide synthase)
SEED: Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)
KEGG: mycobactin polyketide synthetase MbtC

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.3)


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group condition fitness t score  
stress 7H9 with nitrite 1.5 mM; pH 5.5 -2.6 -1.0 compare
carbon source Stearic 100 uM (C) -2.4 -1.4 compare
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM -2.2 -1.3 compare
nitrogen source L-Valine 10 mM (N) -2.2 -1.4 compare
stress 7H9 with Econazole nitrate salt 0.0082 mM -2.0 -1.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.7 -0.8 compare
pH pH 4.5 -1.5 -0.7 compare
stress 7H9 with Benzethonium chloride 0.068 mM -1.5 -1.5 compare
stress 7H9 with Sisomicin 0.07 mM -1.4 -0.8 compare
stress 7H9 with Spectinomycin 0.029 mM -1.4 -1.3 compare
no stress control no stress control -1.3 -1.1 compare
stress 7H9 with Pretomanid 0.213 ug/mL +1.4 +1.3 compare
nitrogen source Urea 10mM (N) +1.5 +2.1 compare
stress 7H9 with Linezolid 0.3 ug/mL +1.5 +1.5 compare
stress 7H9 with nitrite 2.5 mM +1.5 +2.2 compare
stress 7H9 with Ethionamide 0.1 ug/mL +1.6 +1.5 compare
stress 7H9 with Pretomanid 0.213 ug/mL +1.6 +1.3 compare
carbon source cholesterol 100uM (C) +1.8 +2.7 compare
stress 7H9 with Irgasan 0.065 mM +1.9 +2.3 compare
stress 7H9 with nitrite 3 mM; pH 5.5 +2.2 +1.6 compare