Fitness data for Rv2378c in Mycobacterium tuberculosis H37Rv

Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase)
SEED: L-lysine 6-monooxygenase MbtG (EC 1.14.13.59) [mycobactin] siderophore
KEGG: mycobactin lysine-N-oxygenase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.0)


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group condition fitness t score  
stress 7H9 with Erythromycin 0.016 mM -1.4 -2.2 compare
stress 7H9 with Isoniazid 0.025 ug/mL -1.4 -2.1 compare
nitrogen source L-Serine 10 mM (N) -1.3 -2.9 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -1.2 -2.2 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -1.1 -1.8 compare
stress 7H9 with Geneticin G418 0.35 mM -1.1 -1.9 compare
carbon source oleate 200uM (C) -1.1 -1.7 compare
no stress control no stress control -1.0 -1.8 compare
stress 7H9 with Pretomanid 0.213 ug/mL +1.0 +1.5 compare
stress 7H9 with nitrite 2.5 mM +1.1 +1.4 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +1.1 +2.2 compare
stress 7H9 with Rifampicin 0.00045 ug/mL +1.1 +3.0 compare
no stress control no stress control +1.1 +3.7 compare
stress 7H9 with EDTA (disodium salt) 0.2 mM +1.1 +2.0 compare
stress 7H9 with Sisomicin 0.07 mM +1.2 +1.6 compare
stress 7H9 with methylglyoxal 1.2 mM +1.2 +2.7 compare
no stress control no stress control +1.2 +1.9 compare
stress 7H9 with Norfloxacin 0.125 mM +1.4 +2.1 compare
stress 7H9 with nitrate 4 mM +1.5 +2.1 compare
stress 7H9 with Ramoplanin 0.009 mM +1.6 +4.2 compare