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  • Fitness data for Rv2274c in Mycobacterium tuberculosis H37Rv

    Possible toxin MazF8
    SEED: MazF8 antibacterial toxin protein

    Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.7)


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    group condition fitness t score  
    stress 7H9 with Zinc Pyrithione 0.00072 mM -1.5 -2.0 compare
    no stress control no stress control -1.1 -1.7 compare
    stress 7H9 with nitrite 2.5 mM -1.0 -2.1 compare
    stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -1.0 -2.0 compare
    stress 7H9 with Clarithromycin 0.967 ug/mL -1.0 -2.2 compare
    stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.9 -1.7 compare
    stress 7H9 with Hydrogen peroxide 3.97 mM -0.9 -1.8 compare
    stress 7H9 with Doxycycline hyclate 0.0035 mM -0.8 -1.7 compare
    pH pH 5.5 -0.8 -1.4 compare
    stress 7H9 with Lomefloxacin 0.0035 mM -0.8 -1.4 compare
    stress 7H9 with Clofazimine 0.072 ug/mL -0.8 -1.8 compare
    stress 7H9 with Menadione 0.005 mM -0.8 -1.6 compare
    stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.8 -0.9 compare
    stress 7H9 with Sisomicin 0.07 mM -0.8 -1.2 compare
    stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.7 -1.2 compare
    stress 7H9 with Isoniazid 0.025 ug/mL +0.7 +1.7 compare
    stress 7H9 with Linezolid 0.44 ug/mL +0.8 +1.4 compare
    stress 7H9 with Ofloxacin 0.8 ug/mL +0.9 +2.0 compare
    stress 7H9 with nitrite 1.5 mM; pH 5.5 +1.0 +1.0 compare
    stress 7H9 with Levofloxacin 0.3 ug/mL +1.3 +3.2 compare