Fitness data for Rv2259 in Mycobacterium tuberculosis H37Rv

S-nitrosomycothiol reductase MscR
SEED: Formaldehyde dehydrogenase MscR, NAD/mycothiol-dependent (EC 1.2.1.66) / S-nitrosomycothiol reductase MscR
KEGG: S-(hydroxymethyl)mycothiol dehydrogenase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
stress 7H9 with Formaldehyde 0.23 mM -2.5 -2.7 compare
stress 7H9 with methylglyoxal 1.2 mM -1.7 -3.7 compare
stress 7H9 with methylglyoxal 1.2 mM -1.6 -5.3 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -1.0 -2.7 compare
stress 7H9 with Plumbagin 0.01 mM -0.9 -1.6 compare
stress 7H9 with Menadione 0.005 mM -0.9 -2.7 compare
nitrogen source L-Valine 10 mM (N) -0.9 -2.5 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.8 -2.4 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -0.8 -2.3 compare
stress 7H9 with Hydrogen peroxide 3.97 mM -0.8 -2.2 compare
stress 7H9 with Nickel (II) chloride 0.6 mM -0.6 -2.1 compare
pH pH 5.5 -0.6 -1.8 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.6 -1.6 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.6 -1.6 compare
stress 7H9 with Clarithromycin 0.967 ug/mL -0.5 -2.1 compare
pH 7H9 pH 5.5 -0.5 -1.9 compare
no stress control no stress control +0.5 +1.7 compare
nitrogen source L-Asparagine 10 mM (N) +0.5 +1.9 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.6 +1.8 compare
carbon source casaminos 1 mg/mL (C) +0.6 +1.1 compare