Fitness data for Rv2212 in Mycobacterium tuberculosis H37Rv
Adenylyl cyclase (ATP pyrophosphate-lyase) (adenylate cyclase)
SEED: Adenylate cyclase (EC 4.6.1.1)
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)
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| group | condition | fitness | t score | |
|---|---|---|---|---|
| stress | 7H9 with Rifampicin 0.00045 ug/mL | -0.7 | -2.2 | compare |
| no stress control | no stress control | -0.5 | -2.0 | compare |
| no stress control | no stress control | +0.5 | +1.4 | compare |
| carbon source | D-Glucose (C) | +0.5 | +2.8 | compare |
| no stress control | no stress control | +0.5 | +2.1 | compare |
| stress | 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM | +0.6 | +2.1 | compare |
| stress | 7H9 with nitrite 2.5 mM | +0.6 | +1.9 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | +0.6 | +1.1 | compare |
| stress | 7H9 with Levofloxacin 0.3 ug/mL | +0.6 | +2.7 | compare |
| carbon source | L-Lactate 10 mM (C) | +0.6 | +2.0 | compare |
| stress | 7H9 with Ethionamide 0.1 ug/mL | +0.6 | +1.8 | compare |
| no stress control | no stress control | +0.7 | +2.5 | compare |
| no stress control | no stress control | +0.7 | +3.3 | compare |
| stress | 7H9 with Moxifloxacin 0.121 ug/mL | +0.8 | +3.2 | compare |
| no stress control | no stress control | +0.8 | +3.0 | compare |
| stress | 7H9 with Isoniazid 0.025 ug/mL | +0.8 | +2.9 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | +0.8 | +1.9 | compare |
| stress | 7H9 with Isoniazid 0.025 ug/mL | +0.9 | +3.0 | compare |
| nitrogen source | L-Glutamic 10 mM (N) | +0.9 | +1.7 | compare |
| nitrogen source | L-Glutamic 10 mM (N) | +1.0 | +1.6 | compare |