Fitness data for Rv2187 in Mycobacterium tuberculosis H37Rv

Long-chain-fatty-acid-CoA ligase FadD15 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
SEED: Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD15
KEGG: long-chain acyl-CoA synthetase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)


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group condition fitness t score  
stress 7H9 with Chlorpromazine 0.054 mM -0.2 -1.5 compare
stress 7H9 with Dibucaine 0.21 mM +0.2 +1.3 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.2 +1.4 compare
stress 7H9 with Thioridazine 0.028 mM +0.2 +1.6 compare
stress 7H9 with Spectinomycin 0.029 mM +0.2 +1.1 compare
stress 7H9 with Novobiocin 0.004 mM +0.2 +1.5 compare
stress 7H9 with Norfloxacin 0.125 mM +0.2 +1.6 compare
stress 7H9 with Dibucaine 0.21 mM +0.2 +1.5 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.2 +1.6 compare
stress 7H9 with Clofazimine 0.45 ug/mL +0.2 +1.7 compare
stress 7H9 with nitrite 3 mM; pH 5.5 +0.2 +1.6 compare
nitrogen source Ammonium chloride 10mM (N) +0.2 +1.4 compare
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM +0.2 +1.6 compare
stress 7H9 with Phenazine methosulfate 0.0054 mM +0.3 +1.5 compare
no stress control no stress control +0.3 +1.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.4 +2.5 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.4 +2.1 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.4 +2.8 compare
pH pH 4.5 +1.1 +7.2 compare
pH pH 4.5 +1.1 +6.8 compare