Fitness data for Rv2176 in Mycobacterium tuberculosis H37Rv
Probable transmembrane serine/threonine-protein kinase L PknL (protein kinase L) (STPK L)
SEED: Probable serine/threonine-protein kinase pknL (EC 2.7.11.1)
KEGG: serine/threonine protein kinase, bacterial
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)
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| group | condition | fitness | t score | |
|---|---|---|---|---|
| stress | 7H9 with Ethambutol 0.75 ug/mL | -0.7 | -2.2 | compare |
| stress | 7H9 with Hygromycin B 0.0095 mM | -0.6 | -2.8 | compare |
| nitrogen source | L-Glutamic 10 mM (N) | -0.5 | -2.0 | compare |
| stress | 7H9 with Ethambutol 0.75 ug/mL | -0.5 | -1.5 | compare |
| nitrogen source | L-Valine 10 mM (N) | -0.5 | -2.6 | compare |
| stress | 7H9 with Delamanid 0.236 ug/mL | -0.4 | -1.5 | compare |
| carbon source | D-Glucose (C) | -0.3 | -1.8 | compare |
| stress | 7H9 with Rifampicin 0.014 ug/mL | -0.3 | -1.0 | compare |
| nitrogen source | Glycine 10 mM (N) | -0.3 | -1.6 | compare |
| carbon source | acetate (C) | +0.3 | +1.3 | compare |
| carbon source | L-Lactate 10 mM (C) | +0.3 | +1.5 | compare |
| carbon source | Palmitic 100 uM (C) | +0.3 | +1.4 | compare |
| carbon source | casaminos 1 mg/mL (C) | +0.3 | +1.7 | compare |
| carbon source | pyruvate (C) | +0.3 | +1.5 | compare |
| stress | 7H9 with Ofloxacin 0.8 ug/mL | +0.4 | +1.5 | compare |
| no stress control | no stress control | +0.4 | +1.7 | compare |
| carbon source | L-Aspartic Acid (C) | +0.4 | +1.8 | compare |
| no stress control | no stress control | +0.4 | +2.1 | compare |
| carbon source | Glycerol (C) | +0.4 | +2.3 | compare |
| carbon source | Palmitic 100 uM (C) | +0.4 | +2.5 | compare |