Fitness data for Rv2072c in Mycobacterium tuberculosis H37Rv

Precorrin-6Y C(5,15)-methyltransferase (decarboxylating) CobL
SEED: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
KEGG: precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 1.0)


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group condition fitness t score  
stress 7H9 with Moxifloxacin 0.121 ug/mL -2.1 -0.9 compare
pH pH 5.5 -1.4 -1.2 compare
carbon source Palmitic 100 uM (C) -1.3 -1.3 compare
no stress control no stress control -1.2 -1.0 compare
stress 7H9 with Erythromycin 0.016 mM -1.1 -1.3 compare
stress 7H9 with Clofazimine 0.45 ug/mL -1.0 -0.7 compare
stress 7H9 with Lomefloxacin 0.0035 mM -1.0 -0.8 compare
stress 7H9 with Meropenem 9.6 ug/mL +1.0 +1.2 compare
stress 7H9 with Lomefloxacin 0.0035 mM +1.0 +1.3 compare
stress 7H9 with Norfloxacin 0.125 mM +1.0 +1.3 compare
stress 7H9 with Meropenem 9.6 ug/mL +1.0 +1.5 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +1.1 +1.2 compare
nitrogen source L-Alanine 10 mM (N) +1.1 +2.2 compare
stress 7H9 with Rifampicin 0.014 ug/mL +1.2 +1.5 compare
no stress control no stress control +1.2 +1.8 compare
stress 7H9 with Ramoplanin 0.009 mM +1.2 +1.3 compare
stress 7H9 with Clarithromycin 0.967 ug/mL +1.4 +2.2 compare
stress 7H9 with Ethionamide 0.1 ug/mL +1.4 +2.4 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +1.6 +2.0 compare
nitrogen source L-Valine 10 mM (N) +1.7 +3.4 compare