Fitness data for Rv2051c in Mycobacterium tuberculosis H37Rv

Polyprenol-monophosphomannose synthase Ppm1
SEED: Apolipoprotein N-acyltransferase (EC 2.3.1.-) in lipid-linked oligosaccharide synthesis cluster / Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) in lipid-linked oligosaccharide synthesis cluster
KEGG: apolipoprotein N-acyltransferase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.9)


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group condition fitness t score  
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -1.3 -2.2 compare
stress 7H9 with Rifampicin 0.014 ug/mL -1.3 -3.3 compare
stress 7H9 with Sisomicin 0.07 mM -1.2 -2.5 compare
stress 7H9 with Benzethonium chloride 0.068 mM -1.2 -2.8 compare
stress 7H9 with Tetrazolium violet 0.065 mM -1.1 -3.5 compare
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.9 -2.4 compare
stress 7H9 with Bedaquiline 0.15 ug/mL -0.9 -2.8 compare
stress 7H9 with methylglyoxal 1.2 mM -0.9 -2.4 compare
stress 7H9 with Clofazimine 0.45 ug/mL -0.9 -2.5 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.9 -1.6 compare
stress 7H9 with Menadione 0.005 mM +0.9 +3.4 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.9 +3.5 compare
carbon source cholesterol 100uM (C) +0.9 +2.7 compare
stress 7H9 with Menadione 0.005 mM +0.9 +3.2 compare
stress 7H9 with Geneticin G418 0.35 mM +0.9 +3.5 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM +1.0 +2.9 compare
no stress control no stress control +1.1 +4.6 compare
pH pH 4.5 +1.2 +3.5 compare
pH pH 4.5 +1.4 +4.3 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +1.5 +4.9 compare