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  • Fitness data for Rv2043c in Mycobacterium tuberculosis H37Rv

    Pyrazinamidase/nicotinamidase PncA (PZase)
    SEED: Nicotinamidase (EC 3.5.1.19)
    KEGG: nicotinamidase/pyrazinamidase

    Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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    group condition fitness t score  
    stress 7H9 with Doxycycline hyclate 0.0035 mM -0.9 -1.0 compare
    pH pH 4.5 -0.8 -2.1 compare
    carbon source heptadecanoic 250 uM (C) -0.7 -1.9 compare
    stress 7H9 with Chloramphenicol 0.01 mM -0.7 -2.1 compare
    stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.6 -1.8 compare
    stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM -0.6 -2.0 compare
    stress 7H9 with Isoniazid 0.025 ug/mL -0.6 -1.1 compare
    stress 7H9 with Ofloxacin 0.8 ug/mL -0.5 -1.6 compare
    stress 7H9 with Antimycin A 0.0186 mM -0.5 -1.9 compare
    carbon source Valeric 10 mM (C) -0.5 -2.0 compare
    pH pH 4.5 -0.5 -1.5 compare
    stress 7H9 with Menadione 0.005 mM -0.5 -1.7 compare
    stress 7H9 with Meropenem 9.6 ug/mL -0.5 -1.8 compare
    stress 7H9 with Ofloxacin 0.8 ug/mL -0.5 -1.2 compare
    stress 7H9 with Zinc Pyrithione 0.00072 mM +0.5 +1.5 compare
    stress 7H9 with Hydrogen peroxide 3.97 mM +0.6 +1.8 compare
    carbon source D-Trehalose 10 mM (C) +1.0 +2.5 compare
    stress 7H9 with Sisomicin 0.07 mM +1.9 +3.1 compare
    stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +2.2 +4.5 compare
    stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +2.4 +7.9 compare