Fitness data for Rv1940 in Mycobacterium tuberculosis H37Rv

Probable riboflavin biosynthesis protein RibA1 (GTP cyclohydrolase II)
SEED: 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25)
KEGG: 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.7)


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group condition fitness t score  
stress 7H9 with copper (II) chloride 0.08 mM -2.1 -2.7 compare
stress 7H9 with nitrate 4 mM -1.2 -1.8 compare
stress 7H9 with copper (II) chloride 0.08 mM -1.1 -1.8 compare
stress 7H9 with Ofloxacin 0.8 ug/mL -1.1 -1.2 compare
stress 7H9 with Phenazine methosulfate 0.0054 mM -1.1 -2.5 compare
no stress control no stress control -1.0 -1.4 compare
stress 7H9 with Ramoplanin 0.009 mM -1.0 -2.9 compare
stress 7H9 with Ofloxacin 0.8 ug/mL -1.0 -1.1 compare
stress 7H9 with nitrite 2.5 mM -0.9 -1.3 compare
stress 7H9 with Sisomicin 0.07 mM -0.8 -1.3 compare
carbon source propionate (C) -0.8 -2.1 compare
stress 7H9 with Hygromycin B 0.0095 mM -0.8 -1.3 compare
carbon source oleate 200uM (C) -0.8 -1.2 compare
no stress control no stress control -0.8 -1.2 compare
stress 7H9 with methylglyoxal 1.2 mM -0.7 -2.3 compare
stress 7H9 with Dicloxacillin 0.0069 mM -0.7 -1.1 compare
stress 7H9 with nitrite 3 mM; pH 5.5 +0.8 +1.6 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.8 +1.2 compare
stress 7H9 with Zinc Pyrithione 0.00072 mM +1.0 +1.2 compare
stress 7H9 with Linezolid 0.44 ug/mL +1.2 +1.3 compare