Fitness data for Rv1912c in Mycobacterium tuberculosis H37Rv

Possible oxidoreductase FadB5
SEED: (MTCY180.06), len: 334. fadB5, Possible oxidoreductase, similar to hydroxyacyl-CoA dehydrogenase, quinone oxidoreductases (EC 1.6.5.5) and polyketide synthases.Contains quinone oxidoreductase / zeta-crystallin signature(PS01162). FASTA results: Q53927 HYDROXYACYL-COA DEHYDROGENASE. (329 aa) opt: 621; E(): 2e-30; 39.5\% identity in349 aa overlap. Similar to many hypothetical M. tuberculosisproteins including: MTCY24G1.09, MTCY13D12.11, MTCY19H9.01, MTCY24G1.03, MTCY03A2.17c, etc. TBparse score is 0.921
KEGG:

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
stress 7H9 with Erythromycin 0.016 mM -0.8 -1.7 compare
stress 7H9 with Sutezolid 0.12 ug/mL -0.7 -1.4 compare
stress 7H9 with Thioridazine 0.028 mM -0.7 -1.6 compare
pH 7H9 pH 5.5 -0.6 -1.4 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.6 -1.2 compare
stress 7H9 with Nickel (II) chloride 0.6 mM -0.6 -2.1 compare
stress 7H9 with Tetracycline 0.0058 mM -0.6 -1.2 compare
stress 7H9 with Formaldehyde 0.23 mM -0.5 -1.6 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.5 -0.9 compare
stress 7H9 with Sisomicin 0.07 mM +0.5 +1.3 compare
stress 7H9 with Antimycin A 0.0186 mM +0.5 +1.9 compare
carbon source D,L-Malic Acid 10 mM (C) +0.6 +1.3 compare
stress 7H9 with Amikacin di2 ug/mL +0.6 +1.7 compare
nitrogen source L-Serine 10 mM (N) +0.6 +2.0 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.6 +1.6 compare
stress 7H9 with copper (II) chloride 0.08 mM +0.7 +0.9 compare
no stress control no stress control +0.7 +1.9 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.8 +1.1 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.9 +2.1 compare
stress 7H9 with copper (II) chloride 0.08 mM +1.1 +1.8 compare