Fitness data for Rv1843c in Mycobacterium tuberculosis H37Rv

Probable inosine-5'-monophosphate dehydrogenase GuaB1(imp dehydrogenase) (IMPDH) (IMPD)
SEED: Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
KEGG: IMP dehydrogenase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)


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group condition fitness t score  
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.4 -2.3 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.3 -2.2 compare
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.3 -2.3 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.3 -1.5 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.3 -1.9 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.2 +1.5 compare
stress 7H9 with Meropenem 9.6 ug/mL +0.2 +1.4 compare
nitrogen source Ammonium chloride 10mM (N) +0.3 +1.9 compare
nitrogen source L-Glutamine 10 mM (N) +0.3 +1.5 compare
nitrogen source L-Serine 10 mM (N) +0.3 +2.1 compare
carbon source Glycerol (C) +0.3 +2.4 compare
stress 7H9 with Antimycin A 0.0186 mM +0.3 +1.6 compare
nitrogen source L-Glutamic 10 mM (N) +0.3 +1.6 compare
nitrogen source L-Glutamic 10 mM (N) +0.3 +1.5 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.3 +2.1 compare
nitrogen source L-Glutamine 10 mM (N) +0.3 +2.0 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.3 +2.0 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.4 +2.5 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.5 +2.9 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.5 +3.3 compare