Fitness data for Rv1746 in Mycobacterium tuberculosis H37Rv
Anchored-membrane serine/threonine-protein kinase PknF (protein kinase F) (STPK F)
SEED: Serine/threonine-protein kinase PknF (EC 2.7.11.1)
KEGG: serine/threonine protein kinase, bacterial
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)
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group | condition | fitness | t score | |
---|---|---|---|---|
stress | 7H9 with Isoniazid 0.025 ug/mL | -0.5 | -2.8 | compare |
stress | 7H9 with Clarithromycin 0.967 ug/mL | -0.4 | -2.1 | compare |
no stress control | no stress control | -0.4 | -1.8 | compare |
nitrogen source | L-Glutamic 10 mM (N) | -0.4 | -2.0 | compare |
stress | 7H9 with Ofloxacin 0.8 ug/mL | -0.3 | -1.2 | compare |
no stress control | no stress control | -0.3 | -1.5 | compare |
no stress control | no stress control | -0.3 | -1.6 | compare |
stress | 7H9 with Pretomanid 0.213 ug/mL | -0.3 | -1.3 | compare |
stress | 7H9 with Dimethyl Sulfoxide 1 vol% | -0.3 | -1.8 | compare |
stress | 7H9 with Isoniazid 0.025 ug/mL | -0.3 | -0.8 | compare |
nitrogen source | L-Glutamic 10 mM (N) | -0.2 | -1.1 | compare |
stress | 7H9 with Ethionamide 0.1 ug/mL | -0.2 | -0.8 | compare |
carbon source | Palmitic 100 uM (C) | -0.2 | -1.0 | compare |
nitrogen source | L-Serine 10 mM (N) | -0.2 | -1.2 | compare |
nitrogen source | L-Asparagine 10 mM (N) | -0.2 | -1.3 | compare |
carbon source | D,L-Malic Acid 10 mM (C) | +0.2 | +1.1 | compare |
carbon source | Glycerol (C) | +0.2 | +1.6 | compare |
stress | 7H9 with para-aminosalicylic 0.086 ug/mL | +0.3 | +1.5 | compare |
carbon source | acetate (C) | +0.3 | +1.5 | compare |
stress | 7H9 with Rifampicin 0.00045 ug/mL | +0.3 | +1.3 | compare |